Pterygium Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A fleshy mass of thickened conjunctiva that grows over part of the cornea usually from the inner side of the eyeball and causes a disturbance of vision. (BRENDA Tissue and Enzyme Source Ontology, BTO_0005180)
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Genes

116 genes co-occuring with the disease Pterygium in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.801
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.413
IRF6 interferon regulatory factor 6 2.393
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 2.231
RAPSN receptor-associated protein of the synapse 2.224
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.128
RIPK4 receptor-interacting serine-threonine kinase 4 2.088
ECEL1 endothelin converting enzyme-like 1 2.061
FKBP10 FK506 binding protein 10, 65 kDa 2.033
DOK7 docking protein 7 2.0
TPM2 tropomyosin 2 (beta) 1.981
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.952
TNNI2 troponin I type 2 (skeletal, fast) 1.829
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 1.825
TNNT3 troponin T type 3 (skeletal, fast) 1.809
UPK3BL1 uroplakin 3B like 1 1.719
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 1.639
LOXL1 lysyl oxidase-like 1 1.631
PIEZO2 piezo-type mechanosensitive ion channel component 2 1.609
IPO13 importin 13 1.56
GSTM5 glutathione S-transferase mu 5 1.519
KLHL40 kelch-like family member 40 1.517
TP53 tumor protein p53 1.474
IFNA2 interferon, alpha 2 1.468
ECI2 enoyl-CoA delta isomerase 2 1.453
CCDC134 coiled-coil domain containing 134 1.452
TDRD10 tudor domain containing 10 1.438
ZNF254 zinc finger protein 254 1.408
FBN2 fibrillin 2 1.396
CLMN calmin (calponin-like, transmembrane) 1.326
ERCC2 excision repair cross-complementation group 2 1.323
FBXO42 F-box protein 42 1.303
RIPPLY2 ripply transcriptional repressor 2 1.298
OLFML2A olfactomedin-like 2A 1.289
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 1.281
RYR1 ryanodine receptor 1 (skeletal) 1.273
KRT83 keratin 83, type II 1.269
DOP1B DOP1 leucine zipper like protein B 1.267
CRYAA crystallin, alpha A 1.264
GMPPB GDP-mannose pyrophosphorylase B 1.262
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 1.258
PCDHA10 protocadherin alpha 10 1.253
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.253
ACTC1 actin, alpha, cardiac muscle 1 1.241
MMP9 matrix metallopeptidase 9 1.241
CNTN1 contactin 1 1.223
CCIN calicin 1.212
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 1.21
SOS1 son of sevenless homolog 1 (Drosophila) 1.198
ELN elastin 1.19
TGFB1 transforming growth factor, beta 1 1.189
CRYGS crystallin, gamma S 1.186
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 1.174
XPA xeroderma pigmentosum, complementation group A 1.172
ERCC3 excision repair cross-complementation group 3 1.168
IL17RC interleukin 17 receptor C 1.164
TMBIM6 transmembrane BAX inhibitor motif containing 6 1.159
ZDHHC14 zinc finger, DHHC-type containing 14 1.154
SSH1 slingshot protein phosphatase 1 1.151
IFITM5 interferon induced transmembrane protein 5 1.15
LZTR1 leucine-zipper-like transcription regulator 1 1.148
MTIF3 mitochondrial translational initiation factor 3 1.148
TMEM70 transmembrane protein 70 1.145
IFNA16 interferon, alpha 16 1.136
IFNA10 interferon, alpha 10 1.135
IFNA21 interferon, alpha 21 1.135
IFNA14 interferon, alpha 14 1.135
IFNA7 interferon, alpha 7 1.135
IFNA6 interferon, alpha 6 1.134
IFNA8 interferon, alpha 8 1.134
TMPRSS2 transmembrane protease, serine 2 1.133
IFNA5 interferon, alpha 5 1.133
IFNA13 interferon, alpha 13 1.132
ZNF469 zinc finger protein 469 1.131
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 1.13
IFNA4 interferon, alpha 4 1.129
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 1.126
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 1.122
GEMIN4 gem (nuclear organelle) associated protein 4 1.121
FGD1 FYVE, RhoGEF and PH domain containing 1 1.12
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 1.116
ZDHHC4 zinc finger, DHHC-type containing 4 1.114
RBM14-RBM4 RBM14-RBM4 readthrough 1.112
NEB nebulin 1.107
IFNA17 interferon, alpha 17 1.106
RRAS2 related RAS viral (r-ras) oncogene homolog 2 1.085
GAN gigaxonin 1.085
COL1A1 collagen, type I, alpha 1 1.084
COL1A2 collagen, type I, alpha 2 1.079
DMRT2 doublesex and mab-3 related transcription factor 2 1.075
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.068
MTERF1 mitochondrial transcription termination factor 1 1.068
KRT15 keratin 15, type I 1.064
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 1.062
RPH3AL rabphilin 3A-like (without C2 domains) 1.06
TMEM38B transmembrane protein 38B 1.059
MMP1 matrix metallopeptidase 1 1.045
AK9 adenylate kinase 9 1.044
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.043
CRTAP cartilage associated protein 1.037
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 1.035
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 1.029
STAC3 SH3 and cysteine rich domain 3 1.028
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 1.027
TGM2 transglutaminase 2 1.026
PRSS23 protease, serine, 23 1.022
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 1.017
KANK4 KN motif and ankyrin repeat domains 4 1.016
MAP2K2 mitogen-activated protein kinase kinase 2 1.014
MMP3 matrix metallopeptidase 3 1.012
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 1.011
RBM14 RNA binding motif protein 14 1.005
KPNB1 karyopherin (importin) beta 1 1.004
PAX6 paired box 6 1.002
IL1B interleukin 1, beta 1.0
H2AJ H2A.J histone 1.0