Pulmonary Embolism Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An artery disease characterized by a blockage of the main artery of the lung or one of its branches by a substance that has travelled from elsewhere in the body, e.g. a blood clot. (Human Disease Ontology, DOID_9477)
External Link https://www.disgenet.org/browser/0/1/0/C0034065
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Genes

84 genes associated with the disease Pulmonary Embolism in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACVRL1 activin A receptor type II-like 1
AGGF1 angiogenic factor with G patch and FHA domains 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
C4A complement component 4A (Rodgers blood group)
CAT catalase
CBS cystathionine-beta-synthase
CCL2 chemokine (C-C motif) ligand 2
CCN2 cellular communication network factor 2
CCR1 chemokine (C-C motif) receptor 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
COX1
COX2
COX3
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like
CPB2 carboxypeptidase B2 (plasma)
CRP C-reactive protein, pentraxin-related
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
DAB2IP DAB2 interacting protein
EDN1 endothelin 1
ENG endoglin
EPO erythropoietin
ERAP1 endoplasmic reticulum aminopeptidase 1
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FAS Fas cell surface death receptor
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FUNDC2 FUN14 domain containing 2
GDF2 growth differentiation factor 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
HABP2 hyaluronan binding protein 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-B major histocompatibility complex, class I, B
HP haptoglobin
IL10 interleukin 10
IL12A interleukin 12A
IL23R interleukin 23 receptor
JAK2 Janus kinase 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KLRC4 killer cell lectin-like receptor subfamily C, member 4
MEFV Mediterranean fever
MERTK MER proto-oncogene, tyrosine kinase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPL MPL proto-oncogene, thrombopoietin receptor
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
ND1
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLP1 proteolipid protein 1
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROCR protein C receptor, endothelial
PROS1 protein S (alpha)
PTEN phosphatase and tensin homolog
SELENON selenoprotein N
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SLC44A2 solute carrier family 44 (choline transporter), member 2
SMAD4 SMAD family member 4
STAT4 signal transducer and activator of transcription 4
TBXA2R thromboxane A2 receptor
TBXAS1 thromboxane A synthase 1 (platelet)
TET2 tet methylcytosine dioxygenase 2
THBD thrombomodulin
TLR4 toll-like receptor 4
TNNI3 troponin I type 3 (cardiac)
TRIM8 tripartite motif containing 8
TSPAN15 tetraspanin 15
UBAC2 UBA domain containing 2
VCAM1 vascular cell adhesion molecule 1
XDH xanthine dehydrogenase