Pulmonary Hypertension Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.|A syndrome with pathological changes in the pulmonary arteries and impaired PULMONARY CIRCULATION that can be the result of PULMONARY HYPERTENSION. Ayerza syndrome is characterized by slowly developing ASTHMA; BRONCHITIS; DYSPNEA; and CYANOSIS in association with POLYCYTHEMIA. (Experimental Factor Ontology, EFO_0001361)
External Link https://www.disgenet.org/browser/0/1/0/C0020542
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Genes

10 genes associated with the disease Pulmonary Hypertension in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACVRL1 activin A receptor type II-like 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CAV1 caveolin 1, caveolae protein, 22kDa
ENG endoglin
HDAC1 histone deacetylase 1
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
KCNK3 potassium channel, two pore domain subfamily K, member 3
PTCH2 patched 2
SMAD9 SMAD family member 9