Purpura, Thrombotic Thrombocytopenic Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0034155
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Genes

78 genes associated with the disease Purpura, Thrombotic Thrombocytopenic in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
ACSS2 acyl-CoA synthetase short-chain family member 2
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTSL4 ADAMTS-like 4
APOA1 apolipoprotein A-I
APOH apolipoprotein H (beta-2-glycoprotein I)
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C3 complement component 3
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CD19 CD19 molecule
CD248 CD248 molecule, endosialin
CD27 CD27 molecule
CD46 CD46 molecule, complement regulatory protein
CFH complement factor H
CFHR1 complement factor H-related 1
CFHR3 complement factor H-related 3
CFLAR CASP8 and FADD-like apoptosis regulator
CLEC1B C-type lectin domain family 1, member B
COX2
CRISP2 cysteine-rich secretory protein 2
CRP C-reactive protein, pentraxin-related
CSF3 colony stimulating factor 3 (granulocyte)
DGKE diacylglycerol kinase, epsilon 64kDa
ELAVL1 ELAV like RNA binding protein 1
EPHB1 EPH receptor B1
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
FLT4 fms-related tyrosine kinase 4
GHRH growth hormone releasing hormone
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HP haptoglobin
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IL1B interleukin 1, beta
IL33 interleukin 33
JAK2 Janus kinase 2
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KRT20 keratin 20, type I
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PHEX phosphate regulating endopeptidase homolog, X-linked
PKD2L1 polycystic kidney disease 2-like 1
PLA2G15 phospholipase A2, group XV
PLG plasminogen
PRSS55 protease, serine, 55
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTX3 pentraxin 3, long
RBM45 RNA binding motif protein 45
RMDN2 regulator of microtubule dynamics 2
S100B S100 calcium binding protein B
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SH3BP4 SH3-domain binding protein 4
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SPZ1 spermatogenic leucine zipper 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
THBS1 thrombospondin 1
TLR9 toll-like receptor 9
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VWF von Willebrand factor
WAS Wiskott-Aldrich syndrome
ZFP36 ZFP36 ring finger protein