Pyelonephritis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

336 genes co-occuring with the disease Pyelonephritis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CRP C-reactive protein, pentraxin-related 2.992
ALB albumin 2.558
UBAC1 UBA domain containing 1 2.502
UPK1A uroplakin 1A 2.493
IL6 interleukin 6 2.453
LCN2 lipocalin 2 2.386
UMOD uromodulin 2.371
TLR4 toll-like receptor 4 2.349
STRADB STE20-related kinase adaptor beta 2.344
RNASE7 ribonuclease, RNase A family, 7 2.327
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.314
REN renin 2.297
PAPOLG poly(A) polymerase gamma 2.285
IL1B interleukin 1, beta 2.275
KCNIP1 Kv channel interacting protein 1 2.263
TNF tumor necrosis factor 2.258
CXCL8 chemokine (C-X-C motif) ligand 8 2.253
INS insulin 2.21
VIM vimentin 2.206
PCDH8 protocadherin 8 2.199
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.131
ACE angiotensin I converting enzyme 2.13
HAVCR1 hepatitis A virus cellular receptor 1 2.125
HABP2 hyaluronan binding protein 2 2.121
CXCR1 chemokine (C-X-C motif) receptor 1 2.115
CD248 CD248 molecule, endosialin 2.115
UPK3A uroplakin 3A 2.079
B2M beta-2-microglobulin 2.066
OGA O-GlcNAcase 2.06
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2.045
IREB2 iron-responsive element binding protein 2 2.029
OXA1L oxidase (cytochrome c) assembly 1-like 2.01
CD4 CD4 molecule 2.002
F2 coagulation factor II (thrombin) 1.998
TLR5 toll-like receptor 5 1.995
STX2 syntaxin 2 1.971
IL10 interleukin 10 1.967
TLR2 toll-like receptor 2 1.966
IL1A interleukin 1, alpha 1.954
IFNG interferon, gamma 1.94
PTH parathyroid hormone 1.938
CST3 cystatin C 1.929
CAMP cathelicidin antimicrobial peptide 1.923
F3 coagulation factor III (thromboplastin, tissue factor) 1.916
AMBP alpha-1-microglobulin/bikunin precursor 1.912
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.888
CCL2 chemokine (C-C motif) ligand 2 1.868
STX1A syntaxin 1A (brain) 1.867
RNASE6 ribonuclease, RNase A family, k6 1.862
MPO myeloperoxidase 1.857
EPO erythropoietin 1.855
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.839
TLR1 toll-like receptor 1 1.815
DEFB1 defensin, beta 1 1.78
TGFB1 transforming growth factor, beta 1 1.773
LTF lactotransferrin 1.769
IL2 interleukin 2 1.748
CD8A CD8a molecule 1.736
IL17A interleukin 17A 1.73
DPEP1 dipeptidase 1 (renal) 1.728
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.717
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.702
RNF112 ring finger protein 112 1.694
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 1.693
OPRD1 opioid receptor, delta 1 1.692
C3 complement component 3 1.687
AQP2 aquaporin 2 (collecting duct) 1.683
CSF3 colony stimulating factor 3 (granulocyte) 1.675
MYD88 myeloid differentiation primary response 88 1.668
DPP4 dipeptidyl-peptidase 4 1.655
GLI3 GLI family zinc finger 3 1.654
AZU1 azurocidin 1 1.654
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.647
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.646
IL18 interleukin 18 1.642
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.641
IL4 interleukin 4 1.638
FN1 fibronectin 1 1.638
AVP arginine vasopressin 1.607
CD68 CD68 molecule 1.6
KRT7 keratin 7, type II 1.598
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.592
UPK1B uroplakin 1B 1.59
IRF3 interferon regulatory factor 3 1.588
PRADC1 protease-associated domain containing 1 1.582
DEFB4A defensin, beta 4A 1.58
UPK2 uroplakin 2 1.571
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 1.568
TMEM174 transmembrane protein 174 1.564
PTPRC protein tyrosine phosphatase, receptor type, C 1.564
EQTN equatorin, sperm acrosome associated 1.562
CXCL10 chemokine (C-X-C motif) ligand 10 1.555
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.552
HP haptoglobin 1.551
CXCR2 chemokine (C-X-C motif) receptor 2 1.55
MME membrane metallo-endopeptidase 1.535
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.531
PTX3 pentraxin 3, long 1.517
CCL5 chemokine (C-C motif) ligand 5 1.507
APOL1 apolipoprotein L, 1 1.504
PRTN3 proteinase 3 1.491
CRIP3 cysteine-rich protein 3 1.484
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.482
GLP1R glucagon-like peptide 1 receptor 1.474
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.468
ICAM1 intercellular adhesion molecule 1 1.459
THBD thrombomodulin 1.458
RASD2 RASD family, member 2 1.457
KRT20 keratin 20, type I 1.455
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 1.455
PAX2 paired box 2 1.452
CCL20 chemokine (C-C motif) ligand 20 1.451
GCG glucagon 1.448
CCL3 chemokine (C-C motif) ligand 3 1.446
DEFA5 defensin, alpha 5, Paneth cell-specific 1.443
NPPB natriuretic peptide B 1.439
PXDNL peroxidasin-like 1.438
IFNB1 interferon, beta 1, fibroblast 1.437
PXDN peroxidasin 1.437
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.435
PLA2R1 phospholipase A2 receptor 1, 180kDa 1.423
TREM1 triggering receptor expressed on myeloid cells 1 1.423
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.414
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 1.412
AGXT alanine-glyoxylate aminotransferase 1.408
CXCL2 chemokine (C-X-C motif) ligand 2 1.407
CXCL9 chemokine (C-X-C motif) ligand 9 1.405
POMC proopiomelanocortin 1.401
KLK3 kallikrein-related peptidase 3 1.401
CD19 CD19 molecule 1.396
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 1.392
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.391
C5AR1 complement component 5a receptor 1 1.39
NLRP3 NLR family, pyrin domain containing 3 1.389
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.387
CCL4 chemokine (C-C motif) ligand 4 1.383
HAMP hepcidin antimicrobial peptide 1.377
CKM creatine kinase, muscle 1.376
PLG plasminogen 1.376
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.376
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.375
CKMT1B creatine kinase, mitochondrial 1B 1.374
HLA-A major histocompatibility complex, class I, A 1.371
CKB creatine kinase, brain 1.371
CXCL5 chemokine (C-X-C motif) ligand 5 1.371
CA2 carbonic anhydrase II 1.368
IRF7 interferon regulatory factor 7 1.364
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.361
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.357
ACE2 angiotensin I converting enzyme 2 1.352
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.352
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.35
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.343
LY96 lymphocyte antigen 96 1.341
LCN1 lipocalin 1 1.34
MGAM maltase-glucoamylase 1.326
MMP9 matrix metallopeptidase 9 1.322
IL5 interleukin 5 1.322
SCNN1G sodium channel, non voltage gated 1 gamma subunit 1.314
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.313
RNASE8 ribonuclease, RNase A family, 8 1.312
OXT oxytocin/neurophysin I prepropeptide 1.31
VWF von Willebrand factor 1.306
SI sucrase-isomaltase (alpha-glucosidase) 1.303
RAD51 RAD51 recombinase 1.299
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.295
TLR9 toll-like receptor 9 1.284
PGF placental growth factor 1.284
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.279
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.276
MBL2 mannose-binding lectin (protein C) 2, soluble 1.275
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 1.274
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.273
LRP2 low density lipoprotein receptor-related protein 2 1.273
FGF23 fibroblast growth factor 23 1.268
PRKD1 protein kinase D1 1.266
IL1RN interleukin 1 receptor antagonist 1.255
CHRM3 cholinergic receptor, muscarinic 3 1.254
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.253
JUN jun proto-oncogene 1.252
CD34 CD34 molecule 1.25
IFNA1 interferon, alpha 1 1.248
CES5A carboxylesterase 5A 1.248
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.245
MB myoglobin 1.244
EDN1 endothelin 1 1.237
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.233
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.231
FOS FBJ murine osteosarcoma viral oncogene homolog 1.225
ADM adrenomedullin 1.222
LBP lipopolysaccharide binding protein 1.222
SAA1 serum amyloid A1 1.221
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 1.215
IL13 interleukin 13 1.214
C4A complement component 4A (Rodgers blood group) 1.214
CD46 CD46 molecule, complement regulatory protein 1.21
ACTB actin, beta 1.21
HPSE2 heparanase 2 (inactive) 1.205
EGF epidermal growth factor 1.205
PAX8 paired box 8 1.202
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 1.201
AVPR2 arginine vasopressin receptor 2 1.199
SPP1 secreted phosphoprotein 1 1.199
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.184
KNG1 kininogen 1 1.182
ELANE elastase, neutrophil expressed 1.179
CCDC160 coiled-coil domain containing 160 1.177
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.177
CD86 CD86 molecule 1.177
HMGB1 high mobility group box 1 1.173
EMD emerin 1.171
ERVFRD-1 endogenous retrovirus group FRD, member 1 1.17
ERV3-1 endogenous retrovirus group 3, member 1 1.17
ESM1 endothelial cell-specific molecule 1 1.169
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 1.167
DNAH8 dynein, axonemal, heavy chain 8 1.167
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 1.165
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 1.164
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.162
FOXP3 forkhead box P3 1.161
TG thyroglobulin 1.161
TLR3 toll-like receptor 3 1.16
NCAM1 neural cell adhesion molecule 1 1.157
NPPA natriuretic peptide A 1.157
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.156
TIMP1 TIMP metallopeptidase inhibitor 1 1.155
ACR acrosin 1.151
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.149
SAA2 serum amyloid A2 1.146
RNASE3 ribonuclease, RNase A family, 3 1.138
FLII flightless I homolog (Drosophila) 1.137
HLA-B major histocompatibility complex, class I, B 1.135
ERVW-1 endogenous retrovirus group W, member 1 1.135
MMP8 matrix metallopeptidase 8 1.135
TLR6 toll-like receptor 6 1.134
WT1 Wilms tumor 1 1.132
OPRM1 opioid receptor, mu 1 1.132
TNXB tenascin XB 1.131
BCL2 B-cell CLL/lymphoma 2 1.131
TP53 tumor protein p53 1.129
FABP1 fatty acid binding protein 1, liver 1.129
BMP7 bone morphogenetic protein 7 1.128
CXCL12 chemokine (C-X-C motif) ligand 12 1.127
S100A7 S100 calcium binding protein A7 1.126
GATA3 GATA binding protein 3 1.122
AQP1 aquaporin 1 (Colton blood group) 1.121
PIGR polymeric immunoglobulin receptor 1.121
LEP leptin 1.115
MCU mitochondrial calcium uniporter 1.114
CFP complement factor properdin 1.113
DEFA4 defensin, alpha 4, corticostatin 1.113
SDC1 syndecan 1 1.111
IRAK3 interleukin-1 receptor-associated kinase 3 1.111
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 1.11
ENG endoglin 1.106
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.105
RNF123 ring finger protein 123 1.104
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.102
IGFBP7 insulin-like growth factor binding protein 7 1.101
IL9 interleukin 9 1.101
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.099
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 1.094
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.094
ACP7 acid phosphatase 7, tartrate resistant (putative) 1.093
REXO2 RNA exonuclease 2 1.093
ORM2 orosomucoid 2 1.092
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.092
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.091
CFH complement factor H 1.091
TBPL1 TBP-like 1 1.087
SYP synaptophysin 1.085
ACO1 aconitase 1, soluble 1.081
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.08
UPK3B uroplakin 3B 1.08
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.078
PLAT plasminogen activator, tissue 1.077
SELE selectin E 1.076
IL7 interleukin 7 1.073
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.072
AGTR1 angiotensin II receptor, type 1 1.072
MUC1 mucin 1, cell surface associated 1.072
PLXDC1 plexin domain containing 1 1.071
F7 coagulation factor VII (serum prothrombin conversion accelerator) 1.069
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 1.068
TIMP2 TIMP metallopeptidase inhibitor 2 1.066
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 1.063
A2M alpha-2-macroglobulin 1.063
CD40LG CD40 ligand 1.061
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.06
CD38 CD38 molecule 1.059
PKD1 polycystic kidney disease 1 (autosomal dominant) 1.059
ORM1 orosomucoid 1 1.058
CCR2 chemokine (C-C motif) receptor 2 1.056
HMOX1 heme oxygenase 1 1.054
VCAM1 vascular cell adhesion molecule 1 1.053
CD80 CD80 molecule 1.052
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.052
RNASE4 ribonuclease, RNase A family, 4 1.051
C5AR2 complement component 5a receptor 2 1.051
CXCL13 chemokine (C-X-C motif) ligand 13 1.05
MIOX myo-inositol oxygenase 1.049
SUFU suppressor of fused homolog (Drosophila) 1.048
TTR transthyretin 1.046
PYCARD PYD and CARD domain containing 1.045
SELL selectin L 1.042
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.041
EYA1 EYA transcriptional coactivator and phosphatase 1 1.04
CD163 CD163 molecule 1.039
MCOLN3 mucolipin 3 1.037
G6PD glucose-6-phosphate dehydrogenase 1.034
IL15 interleukin 15 1.034
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.032
IL1R1 interleukin 1 receptor, type I 1.032
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 1.032
PECAM1 platelet/endothelial cell adhesion molecule 1 1.03
GGT6 gamma-glutamyltransferase 6 1.028
TLR10 toll-like receptor 10 1.026
HBD hemoglobin, delta 1.023
GBGT1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 1.023
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.023
ADIPOQ adiponectin, C1Q and collagen domain containing 1.019
S100A8 S100 calcium binding protein A8 1.019
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.017
RBMS2 RNA binding motif, single stranded interacting protein 2 1.017
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.015
XDH xanthine dehydrogenase 1.011
MAPK3 mitogen-activated protein kinase 3 1.01
LTA lymphotoxin alpha 1.009
GGT7 gamma-glutamyltransferase 7 1.007
LGALS3 lectin, galactoside-binding, soluble, 3 1.006
STAP2 signal transducing adaptor family member 2 1.006
CFB complement factor B 1.006
CLEC4E C-type lectin domain family 4, member E 1.005
RNASET2 ribonuclease T2 1.003
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.003
CD40 CD40 molecule, TNF receptor superfamily member 5 1.0