| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.248863 |
| CD44 | CD44 molecule (Indian blood group) | 0.152538 |
| NAV1 | neuron navigator 1 | 0.0934456 |
| FLNA | filamin A, alpha | 0.0930742 |
| MAP1B | microtubule-associated protein 1B | 0.0903476 |
| GLIS3 | GLIS family zinc finger 3 | 0.0896318 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0837008 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0831885 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0828884 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0787569 |
| DST | dystonin | 0.0774743 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0732125 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0723421 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0717249 |
| ASPH | aspartate beta-hydroxylase | 0.0655158 |
| VCL | vinculin | 0.0623277 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0616539 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0601695 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0597144 |
| THBS2 | thrombospondin 2 | 0.0591695 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0574546 |
| VEGFC | vascular endothelial growth factor C | 0.0561521 |
| FLNB | filamin B, beta | 0.0513077 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0499388 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0499106 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0495532 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.049051 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0486516 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.047451 |
| LOX | lysyl oxidase | 0.0474418 |
| MB21D2 | Mab-21 domain containing 2 | 0.0450053 |
| SMAD3 | SMAD family member 3 | 0.0445649 |
| EHBP1 | EH domain binding protein 1 | 0.0444257 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0438777 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0421837 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0412072 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0409924 |
| RAI14 | retinoic acid induced 14 | 0.0401672 |
| MSN | moesin | 0.0396669 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0391449 |
| SP100 | SP100 nuclear antigen | 0.0380441 |
| EFNA5 | ephrin-A5 | 0.0370401 |
| DNMBP | dynamin binding protein | 0.0365107 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0365105 |
| DCLK2 | doublecortin-like kinase 2 | 0.0359536 |
| LAMB1 | laminin, beta 1 | 0.0357434 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0356975 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0355466 |
| SVIL | supervillin | 0.0351204 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0342107 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0341554 |
| TPM3 | tropomyosin 3 | 0.0331226 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0329159 |
| ANO6 | anoctamin 6 | 0.0316668 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0315312 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0313989 |
| SMYD3 | SET and MYND domain containing 3 | 0.0310416 |
| PLEC | plectin | 0.0306969 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0306952 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0304621 |
| SON | SON DNA binding protein | 0.0304375 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0302863 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0301909 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0301347 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0298215 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.029468 |
| FSTL1 | follistatin-like 1 | 0.0294621 |
| ERBIN | erbb2 interacting protein | 0.0287623 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0287553 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0275353 |
| MKI67 | marker of proliferation Ki-67 | 0.0266572 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0265696 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0264125 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0263984 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0261625 |
| ITGA6 | integrin, alpha 6 | 0.0260125 |
| RNF213 | ring finger protein 213 | 0.0258003 |
| NCKAP1 | NCK-associated protein 1 | 0.0255963 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0255189 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0253944 |
| RNF144A | ring finger protein 144A | 0.0249358 |
| FN1 | fibronectin 1 | 0.0248597 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0242878 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.024227 |
| MYOF | myoferlin | 0.0240333 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0238512 |
| OSMR | oncostatin M receptor | 0.0235195 |
| KIAA1549L | KIAA1549-like | 0.0234471 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0232636 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0232122 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.023166 |
| FUS | FUS RNA binding protein | 0.0230567 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0227776 |
| TXNRD1 | thioredoxin reductase 1 | 0.0226659 |
| EZR | ezrin | 0.0221323 |
| FAT1 | FAT atypical cadherin 1 | 0.0220037 |
| KLF12 | Kruppel-like factor 12 | 0.0217748 |
| DSPP | dentin sialophosphoprotein | 0.0216348 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0215956 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0213729 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.22851 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.191251 |
| TMSB10 | thymosin beta 10 | -0.183061 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.114835 |
| NDRG1 | N-myc downstream regulated 1 | -0.105055 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0981901 |
| VIM | vimentin | -0.0923206 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0844329 |
| MSI2 | musashi RNA-binding protein 2 | -0.0832415 |
| S100A6 | S100 calcium binding protein A6 | -0.0791853 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0737774 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.071253 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0680041 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0663134 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0651793 |
| MT2A | metallothionein 2A | -0.065015 |
| PTMA | prothymosin, alpha | -0.0634273 |
| AUTS2 | autism susceptibility candidate 2 | -0.0634039 |
| SUCNR1 | succinate receptor 1 | -0.0612318 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.060603 |
| NAV2 | neuron navigator 2 | -0.0599162 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0584565 |
| CSTB | cystatin B (stefin B) | -0.0581873 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0579376 |
| CD109 | CD109 molecule | -0.053263 |
| CCND1 | cyclin D1 | -0.0509479 |
| HLA-B | major histocompatibility complex, class I, B | -0.0498481 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0492888 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0478534 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0476894 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0457217 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0456339 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0454969 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0444182 |
| INSIG1 | insulin induced gene 1 | -0.0435715 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0418764 |
| S100A10 | S100 calcium binding protein A10 | -0.0409165 |
| TAGLN2 | transgelin 2 | -0.0403441 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0392113 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0390451 |
| LOXL2 | lysyl oxidase-like 2 | -0.0385312 |
| RPS24 | ribosomal protein S24 | -0.0384568 |
| B2M | beta-2-microglobulin | -0.0378487 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.036376 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0360831 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0360482 |
| LDHA | lactate dehydrogenase A | -0.0358868 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0357585 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0356987 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0355696 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0354176 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0350763 |
| MEIS2 | Meis homeobox 2 | -0.0350205 |
| CD99 | CD99 molecule | -0.0348081 |
| SQSTM1 | sequestosome 1 | -0.0347725 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0343881 |
| MMP12 | matrix metallopeptidase 12 | -0.0342299 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0339474 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0334105 |
| RPL35A | ribosomal protein L35a | -0.0328928 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0327936 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0326266 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0323674 |
| FTL | ferritin, light polypeptide | -0.0319747 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0313784 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0313091 |
| RND3 | Rho family GTPase 3 | -0.0311809 |
| GOLGA4 | golgin A4 | -0.0309575 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0308524 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.030253 |
| FNIP1 | folliculin interacting protein 1 | -0.0300602 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0293982 |
| HLA-C | major histocompatibility complex, class I, C | -0.0293913 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0285655 |
| RPL34 | ribosomal protein L34 | -0.0281535 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0279802 |
| SEC24A | SEC24 family member A | -0.0276451 |
| TNS3 | tensin 3 | -0.0272478 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0272252 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0271353 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0270717 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0269008 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0267028 |
| CYLD | cylindromatosis (turban tumor syndrome) | -0.0266264 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0262923 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0259303 |
| COL5A1 | collagen, type V, alpha 1 | -0.0256103 |
| POTEF | POTE ankyrin domain family, member F | -0.0255603 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0254292 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0248434 |
| RPL28 | ribosomal protein L28 | -0.0245632 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0244534 |
| ACTG1 | actin gamma 1 | -0.0243359 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0241321 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.0241243 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0237237 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0236342 |
| S100A4 | S100 calcium binding protein A4 | -0.023467 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.023436 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0233492 |
