| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.235952 |
| FLNB | filamin B, beta | 0.088932 |
| LAMA4 | laminin, alpha 4 | 0.0722277 |
| EMP1 | epithelial membrane protein 1 | 0.0619082 |
| SGMS2 | sphingomyelin synthase 2 | 0.0539679 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0520415 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0486196 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0469866 |
| TGM2 | transglutaminase 2 | 0.0460503 |
| ITGA6 | integrin, alpha 6 | 0.0453936 |
| EGFR | epidermal growth factor receptor | 0.0440855 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0429291 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0420202 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0414472 |
| UBC | ubiquitin C | 0.0410753 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.038906 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.03794 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0367265 |
| FLNA | filamin A, alpha | 0.0363599 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0357924 |
| PLEC | plectin | 0.0353039 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.032878 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0325915 |
| CD44 | CD44 molecule (Indian blood group) | 0.032458 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0312061 |
| DSPP | dentin sialophosphoprotein | 0.0310792 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0306853 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.030198 |
| MSN | moesin | 0.0300932 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0289266 |
| GDA | guanine deaminase | 0.0286402 |
| VCAN | versican | 0.0285218 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0276866 |
| FAT1 | FAT atypical cadherin 1 | 0.0271839 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 0.0245718 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0243876 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.023908 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0238411 |
| HDAC9 | histone deacetylase 9 | 0.0236782 |
| AREG | amphiregulin | 0.0236457 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.023508 |
| HMGA2 | high mobility group AT-hook 2 | 0.0232803 |
| TBC1D5 | TBC1 domain family, member 5 | 0.022929 |
| MMP1 | matrix metallopeptidase 1 | 0.0229086 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0229067 |
| LMNA | lamin A/C | 0.0226166 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0221582 |
| FMNL2 | formin-like 2 | 0.0220126 |
| PCDH1 | protocadherin 1 | 0.0213461 |
| SEPTIN9 | septin 9 | 0.0211589 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.021104 |
| BMP6 | bone morphogenetic protein 6 | 0.0207089 |
| MX1 | MX dynamin-like GTPase 1 | 0.020676 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0204159 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0201592 |
| AHR | aryl hydrocarbon receptor | 0.0201585 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0201347 |
| ANXA1 | annexin A1 | 0.0201133 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0200911 |
| MYOF | myoferlin | 0.0199567 |
| TXNRD1 | thioredoxin reductase 1 | 0.0199396 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0194416 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0191817 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0191571 |
| FHL2 | four and a half LIM domains 2 | 0.0190744 |
| CCNL1 | cyclin L1 | 0.0188179 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0187364 |
| TMEM117 | transmembrane protein 117 | 0.0185926 |
| SERTAD2 | SERTA domain containing 2 | 0.0185776 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0181483 |
| KIAA0040 | KIAA0040 | 0.0181145 |
| WDR43 | WD repeat domain 43 | 0.0180993 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0179982 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.017929 |
| MCL1 | myeloid cell leukemia 1 | 0.0177459 |
| EFNB2 | ephrin-B2 | 0.017709 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0172523 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0170576 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 0.0169845 |
| ADAR | adenosine deaminase, RNA-specific | 0.0169756 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0169169 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0168333 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0168297 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0167533 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0166588 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0165899 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0165706 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0165441 |
| STK17B | serine/threonine kinase 17b | 0.0163993 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0163004 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0162212 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0161341 |
| STC1 | stanniocalcin 1 | 0.0161134 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0160769 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0158653 |
| PCM1 | pericentriolar material 1 | 0.0158349 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0157668 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0156704 |
| MLF1 | myeloid leukemia factor 1 | 0.0156201 |
| MYO1E | myosin IE | 0.0155967 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | -0.229758 |
| TMSB10 | thymosin beta 10 | -0.177516 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.152858 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.146113 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.137872 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.117995 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.106158 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.105072 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0935695 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0930606 |
| TPM4 | tropomyosin 4 | -0.0785563 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0742271 |
| VIM | vimentin | -0.0706636 |
| LMO7 | LIM domain 7 | -0.0693006 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0685674 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0681501 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0610383 |
| CD2AP | CD2-associated protein | -0.0575395 |
| FTL | ferritin, light polypeptide | -0.0571296 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0566573 |
| SDC4 | syndecan 4 | -0.0549741 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0546286 |
| MORF4L2 | mortality factor 4 like 2 | -0.0543157 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0539615 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0539281 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0533566 |
| PGK1 | phosphoglycerate kinase 1 | -0.052447 |
| PTMA | prothymosin, alpha | -0.0521575 |
| RRBP1 | ribosome binding protein 1 | -0.0515687 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.051549 |
| GNAS | GNAS complex locus | -0.0514924 |
| B2M | beta-2-microglobulin | -0.0506191 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0505457 |
| TAOK3 | TAO kinase 3 | -0.0485951 |
| RIOK3 | RIO kinase 3 | -0.046163 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0458886 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0451323 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0450108 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0449117 |
| MXD1 | MAX dimerization protein 1 | -0.0445706 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0442816 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0442485 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.043076 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0430011 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0423353 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0406634 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.040504 |
| USP34 | ubiquitin specific peptidase 34 | -0.0402658 |
| CD164 | CD164 molecule, sialomucin | -0.0395793 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0395781 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0393302 |
| RPS8 | ribosomal protein S8 | -0.0387771 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0383671 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0382699 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0381513 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.037786 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0374915 |
| OGA | O-GlcNAcase | -0.0373739 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0370642 |
| SPAG9 | sperm associated antigen 9 | -0.0365227 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0363326 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0361504 |
| PRSS3 | protease, serine, 3 | -0.0357646 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.035653 |
| SEPTIN10 | septin 10 | -0.0349899 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0348747 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0341198 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0339756 |
| SQSTM1 | sequestosome 1 | -0.0339566 |
| SLMAP | sarcolemma associated protein | -0.0338047 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0335365 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0333956 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0332071 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0330183 |
| PTK2 | protein tyrosine kinase 2 | -0.033015 |
| RPL26 | ribosomal protein L26 | -0.0329662 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.032889 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0327158 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0327006 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0323952 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0320638 |
| CLMP | CXADR-like membrane protein | -0.031954 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0317531 |
| CEP350 | centrosomal protein 350kDa | -0.0317303 |
| UPP1 | uridine phosphorylase 1 | -0.0317169 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0313371 |
| PARD3 | par-3 family cell polarity regulator | -0.0313212 |
| GRB10 | growth factor receptor-bound protein 10 | -0.031234 |
| FBXO11 | F-box protein 11 | -0.0311694 |
| RESF1 | retroelement silencing factor 1 | -0.0308479 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0304177 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0302421 |
| RPL37 | ribosomal protein L37 | -0.0300446 |
| MTDH | metadherin | -0.0298318 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.029775 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0297713 |
| HLA-E | major histocompatibility complex, class I, E | -0.0296895 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0296697 |
| RPS3 | ribosomal protein S3 | -0.0294099 |
| ANXA2 | annexin A2 | -0.0293055 |
