| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.100206 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0877601 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0857391 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0798642 |
| SET | SET nuclear proto-oncogene | 0.0794355 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0785971 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0779894 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0778495 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0706551 |
| SP100 | SP100 nuclear antigen | 0.0635594 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0625801 |
| SLFN5 | schlafen family member 5 | 0.0613336 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0608697 |
| MCL1 | myeloid cell leukemia 1 | 0.0568253 |
| VCP | valosin containing protein | 0.0541026 |
| APP | amyloid beta (A4) precursor protein | 0.0531518 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0504606 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0503084 |
| ENO1 | enolase 1, (alpha) | 0.0498363 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0479672 |
| TXNRD1 | thioredoxin reductase 1 | 0.047915 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.047544 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0472443 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0470597 |
| DSPP | dentin sialophosphoprotein | 0.0468031 |
| PLSCR1 | phospholipid scramblase 1 | 0.0467491 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0458029 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0455628 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0453901 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.045284 |
| RPS12 | ribosomal protein S12 | 0.0449861 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0439994 |
| CDK12 | cyclin-dependent kinase 12 | 0.0438538 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0434222 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0429216 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0425866 |
| SMYD3 | SET and MYND domain containing 3 | 0.0422827 |
| KIF5B | kinesin family member 5B | 0.0413852 |
| PMP22 | peripheral myelin protein 22 | 0.0411902 |
| SBF2 | SET binding factor 2 | 0.0411229 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0407288 |
| ADAR | adenosine deaminase, RNA-specific | 0.0401686 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0398217 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0391244 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0385554 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0378516 |
| AHR | aryl hydrocarbon receptor | 0.0376724 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0373388 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0371433 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0370215 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0366649 |
| RPS6 | ribosomal protein S6 | 0.0363036 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.03586 |
| TC2N | tandem C2 domains, nuclear | 0.0358159 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0357725 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0354471 |
| CTTN | cortactin | 0.0352016 |
| KIAA1217 | KIAA1217 | 0.0351756 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0351589 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0350375 |
| RPS3 | ribosomal protein S3 | 0.0348088 |
| MX1 | MX dynamin-like GTPase 1 | 0.0346666 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.034428 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.034349 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0340412 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0336418 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0330038 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0328682 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0324855 |
| NRP1 | neuropilin 1 | 0.032341 |
| TPM3 | tropomyosin 3 | 0.0318985 |
| PLK2 | polo-like kinase 2 | 0.031869 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0317861 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0317399 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0316432 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0315863 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0311443 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0310991 |
| GPHN | gephyrin | 0.0310712 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0307981 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0307031 |
| RPS2 | ribosomal protein S2 | 0.0305035 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0296783 |
| PNN | pinin, desmosome associated protein | 0.0296266 |
| CALR | calreticulin | 0.0295334 |
| CANX | calnexin | 0.0293694 |
| USO1 | USO1 vesicle transport factor | 0.0289903 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0287213 |
| VEGFA | vascular endothelial growth factor A | 0.0285591 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0282433 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0281811 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0278218 |
| USP47 | ubiquitin specific peptidase 47 | 0.0276144 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.027594 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0275314 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.027122 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0269969 |
| ABHD17C | abhydrolase domain containing 17C | 0.0268571 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0268549 |
| MT2A | metallothionein 2A | 0.0266944 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.156733 |
| LASP1 | LIM and SH3 protein 1 | -0.13511 |
| RPL23 | ribosomal protein L23 | -0.12939 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.129368 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.121316 |
| TMSB10 | thymosin beta 10 | -0.0774373 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0703242 |
| RPL35A | ribosomal protein L35a | -0.069174 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0643065 |
| POTEF | POTE ankyrin domain family, member F | -0.061568 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0608932 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0563446 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0516146 |
| TMEM123 | transmembrane protein 123 | -0.0515599 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0513949 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0491651 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0426353 |
| FASN | fatty acid synthase | -0.0421892 |
| TMSB4X | thymosin beta 4, X-linked | -0.0419617 |
| TENM2 | teneurin transmembrane protein 2 | -0.041525 |
| RPL34 | ribosomal protein L34 | -0.0411586 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0399301 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0383379 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0381606 |
| GNAS | GNAS complex locus | -0.0371115 |
| MIDN | midnolin | -0.0365264 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0364849 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.035075 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0348637 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0346679 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0344209 |
| KRT8 | keratin 8, type II | -0.0341339 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.033829 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0335516 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0333072 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0331073 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0330921 |
| FADS2 | fatty acid desaturase 2 | -0.0330089 |
| RPS19 | ribosomal protein S19 | -0.0327675 |
| S100A6 | S100 calcium binding protein A6 | -0.0325759 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0324797 |
| CCND1 | cyclin D1 | -0.0324245 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0321793 |
| RPL19 | ribosomal protein L19 | -0.031776 |
| ACTG1 | actin gamma 1 | -0.0313657 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0312872 |
| VCL | vinculin | -0.0311079 |
| NDRG1 | N-myc downstream regulated 1 | -0.0307536 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0299421 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0296183 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.029526 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0288504 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0281965 |
| S100A14 | S100 calcium binding protein A14 | -0.0280487 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0277689 |
| GATA3 | GATA binding protein 3 | -0.0274836 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0274146 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0271767 |
| RPS24 | ribosomal protein S24 | -0.0271573 |
| RPL12 | ribosomal protein L12 | -0.0271078 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0270931 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0269375 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0263078 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0262086 |
| CD164 | CD164 molecule, sialomucin | -0.0255473 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0253685 |
| HMGB1 | high mobility group box 1 | -0.0252796 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0245365 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0244493 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) | -0.0238207 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -0.0238204 |
| PERP | PERP, TP53 apoptosis effector | -0.0236924 |
| TUBB | tubulin, beta class I | -0.0236288 |
| KAZN | kazrin, periplakin interacting protein | -0.0235851 |
| CD24 | CD24 molecule | -0.0235273 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0231871 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -0.0231677 |
| TOB1 | transducer of ERBB2, 1 | -0.022769 |
| KIF16B | kinesin family member 16B | -0.0226413 |
| TMEM41B | transmembrane protein 41B | -0.0225314 |
| YPEL2 | yippee-like 2 (Drosophila) | -0.0222802 |
| DEK | DEK proto-oncogene | -0.0221548 |
| RRBP1 | ribosome binding protein 1 | -0.0220321 |
| EGR1 | early growth response 1 | -0.0219359 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0218075 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | -0.0215005 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0214948 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 | -0.0214863 |
| MGP | matrix Gla protein | -0.021424 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0214113 |
| MSI2 | musashi RNA-binding protein 2 | -0.0209441 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0207066 |
| CCNI | cyclin I | -0.0206144 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0204073 |
| HMGA1 | high mobility group AT-hook 1 | -0.0200277 |
| TTC6 | tetratricopeptide repeat domain 6 | -0.0198626 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0197858 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0196991 |
| ACTN4 | actinin, alpha 4 | -0.0192972 |
| GSE1 | Gse1 coiled-coil protein | -0.0192565 |
