| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.205013 |
| FRMD4A | FERM domain containing 4A | 0.124138 |
| ASPH | aspartate beta-hydroxylase | 0.115058 |
| DST | dystonin | 0.10187 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.100675 |
| GPC6 | glypican 6 | 0.0983797 |
| NLGN1 | neuroligin 1 | 0.0931695 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0798983 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0788159 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0782291 |
| VIM | vimentin | 0.0780992 |
| MACROD2 | MACRO domain containing 2 | 0.0739407 |
| TNNC1 | troponin C type 1 (slow) | 0.0704972 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0685465 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0556132 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0539687 |
| PCDH7 | protocadherin 7 | 0.0520054 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0516081 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0513713 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0510191 |
| SFTPA2 | surfactant protein A2 | 0.0497619 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.044159 |
| FN1 | fibronectin 1 | 0.0424103 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0409508 |
| FLNA | filamin A, alpha | 0.0407893 |
| SMYD3 | SET and MYND domain containing 3 | 0.0398582 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0397173 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0392874 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0390418 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0385762 |
| FMN1 | formin 1 | 0.038141 |
| LAMB1 | laminin, beta 1 | 0.0361633 |
| NAV1 | neuron navigator 1 | 0.034606 |
| RNF213 | ring finger protein 213 | 0.0345541 |
| NAV3 | neuron navigator 3 | 0.0342038 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0341064 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0341063 |
| FRMD6 | FERM domain containing 6 | 0.0339736 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0338904 |
| SETBP1 | SET binding protein 1 | 0.0336767 |
| NRP2 | neuropilin 2 | 0.0330331 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0328561 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0322976 |
| PRELID2 | PRELI domain containing 2 | 0.0319034 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0318134 |
| AHNAK | AHNAK nucleoprotein | 0.0308818 |
| EFNA5 | ephrin-A5 | 0.0303834 |
| RAD51B | RAD51 paralog B | 0.0298202 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0296638 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0296434 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0294459 |
| FBXO32 | F-box protein 32 | 0.0289538 |
| ENO1 | enolase 1, (alpha) | 0.0282267 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0279592 |
| WWOX | WW domain containing oxidoreductase | 0.0278544 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0268597 |
| FAT1 | FAT atypical cadherin 1 | 0.0268067 |
| AFAP1 | actin filament associated protein 1 | 0.0262983 |
| CUL4B | cullin 4B | 0.0258497 |
| ADM | adrenomedullin | 0.0257456 |
| CD44 | CD44 molecule (Indian blood group) | 0.02573 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0257277 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0255597 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0252912 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0249997 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0240315 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0238962 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.023836 |
| ATP11A | ATPase, class VI, type 11A | 0.0233819 |
| NEGR1 | neuronal growth regulator 1 | 0.023243 |
| LSAMP | limbic system-associated membrane protein | 0.0231946 |
| SUMF1 | sulfatase modifying factor 1 | 0.022963 |
| BRD2 | bromodomain containing 2 | 0.0225561 |
| EXOC4 | exocyst complex component 4 | 0.0223888 |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | 0.022364 |
| ATXN1 | ataxin 1 | 0.0222622 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0222471 |
| MAP1B | microtubule-associated protein 1B | 0.0220895 |
| A2M | alpha-2-macroglobulin | 0.0220826 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0220425 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.021928 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.021748 |
| UTRN | utrophin | 0.0217014 |
| MYO10 | myosin X | 0.0216125 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0215854 |
| STAMBPL1 | STAM binding protein-like 1 | 0.0215743 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0215238 |
| HSPA8 | heat shock 70kDa protein 8 | 0.021417 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0213667 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0212151 |
| FGGY | FGGY carbohydrate kinase domain containing | 0.0211847 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0209922 |
| TNS3 | tensin 3 | 0.0209476 |
| RNF150 | ring finger protein 150 | 0.0208278 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0206535 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.020444 |
| MT2A | metallothionein 2A | 0.0204269 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0202732 |
| AFAP1L1 | actin filament associated protein 1-like 1 | 0.0198424 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0191176 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.160226 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.103103 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.100571 |
| CD109 | CD109 molecule | -0.0901579 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0898208 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0883899 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0865463 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0854386 |
| GDF15 | growth differentiation factor 15 | -0.0846237 |
| SBF2 | SET binding factor 2 | -0.0795411 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.078307 |
| EGR1 | early growth response 1 | -0.0731103 |
| COPA | coatomer protein complex, subunit alpha | -0.0722607 |
| CDC73 | cell division cycle 73 | -0.0720339 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0714902 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0713829 |
| CALU | calumenin | -0.0673053 |
| NAV2 | neuron navigator 2 | -0.0669347 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0668719 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0649075 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0648209 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0629373 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0609462 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0586239 |
| VCL | vinculin | -0.0580891 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0567462 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0557097 |
| NBAS | neuroblastoma amplified sequence | -0.0552846 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0548513 |
| CUX1 | cut-like homeobox 1 | -0.0547093 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0536604 |
| TAGLN2 | transgelin 2 | -0.0515351 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0498859 |
| PTCHD4 | patched domain containing 4 | -0.0496584 |
| COG5 | component of oligomeric golgi complex 5 | -0.0492924 |
| GOLGA4 | golgin A4 | -0.0491952 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0482406 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.048235 |
| SRPK2 | SRSF protein kinase 2 | -0.0477737 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0476992 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0474596 |
| HELZ | helicase with zinc finger | -0.0473178 |
| RBM33 | RNA binding motif protein 33 | -0.0467723 |
| BBX | bobby sox homolog (Drosophila) | -0.0463659 |
| RNF145 | ring finger protein 145 | -0.0452372 |
| TPD52 | tumor protein D52 | -0.0446638 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0444798 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0430741 |
| MEF2A | myocyte enhancer factor 2A | -0.0427567 |
| TMEM123 | transmembrane protein 123 | -0.0423391 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0422278 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0402803 |
| CABIN1 | calcineurin binding protein 1 | -0.040264 |
| CALD1 | caldesmon 1 | -0.0401513 |
| FNIP1 | folliculin interacting protein 1 | -0.0395781 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0386052 |
| SCFD2 | sec1 family domain containing 2 | -0.0381809 |
| NDRG1 | N-myc downstream regulated 1 | -0.0374067 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0372662 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0368078 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.036506 |
| NF1 | neurofibromin 1 | -0.0361833 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0356846 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0352468 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0347809 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0343614 |
| RUNX1 | runt-related transcription factor 1 | -0.0339224 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0338309 |
| SETD5 | SET domain containing 5 | -0.0337852 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0335723 |
| GHR | growth hormone receptor | -0.0334478 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0333565 |
| MTPN | myotrophin | -0.0330246 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0328045 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0324698 |
| RCOR1 | REST corepressor 1 | -0.0323961 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0323525 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0322796 |
| TAOK1 | TAO kinase 1 | -0.0317912 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0314767 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.031148 |
| NUP58 | nucleoporin 58 | -0.0306585 |
| PTK2 | protein tyrosine kinase 2 | -0.0304383 |
| POTEF | POTE ankyrin domain family, member F | -0.0303156 |
| POM121 | POM121 transmembrane nucleoporin | -0.0302627 |
| PCNX1 | pecanex 1 | -0.0302121 |
| RTN4 | reticulon 4 | -0.0302106 |
| MED13 | mediator complex subunit 13 | -0.0299911 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0299671 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0297842 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0297062 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0294258 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0293729 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0292895 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0291597 |
| PYGB | phosphorylase, glycogen; brain | -0.0291446 |
| ATF6 | activating transcription factor 6 | -0.0287167 |
| HDAC9 | histone deacetylase 9 | -0.0284754 |
| RHOA | ras homolog family member A | -0.0283042 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0282886 |
