| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pyridoxine (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.0821905 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0720497 |
| APOL1 | apolipoprotein L, 1 | 0.0706508 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0651905 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0636353 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0533052 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0477914 |
| BICC1 | BicC family RNA binding protein 1 | 0.0474323 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0468263 |
| SP100 | SP100 nuclear antigen | 0.0448233 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0432139 |
| TGM2 | transglutaminase 2 | 0.0417388 |
| KYNU | kynureninase | 0.0395137 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0390765 |
| RIGI | RNA sensor RIG-I | 0.0363751 |
| MX1 | MX dynamin-like GTPase 1 | 0.0358957 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0355047 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0354275 |
| PDZD8 | PDZ domain containing 8 | 0.0353938 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0353569 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0333803 |
| LAMA4 | laminin, alpha 4 | 0.0324514 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0321307 |
| MYO1E | myosin IE | 0.0306119 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0303689 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0302497 |
| EHBP1 | EH domain binding protein 1 | 0.0301768 |
| CP | ceruloplasmin (ferroxidase) | 0.0299638 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0297683 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0283315 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0279968 |
| C3 | complement component 3 | 0.0279078 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0278747 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0274668 |
| HDAC9 | histone deacetylase 9 | 0.0268973 |
| NTN4 | netrin 4 | 0.0258282 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0250187 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0249119 |
| DSPP | dentin sialophosphoprotein | 0.0248404 |
| RAB10 | RAB10, member RAS oncogene family | 0.0248272 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0242943 |
| FHL2 | four and a half LIM domains 2 | 0.023734 |
| SGMS2 | sphingomyelin synthase 2 | 0.022953 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0229355 |
| IFI44L | interferon-induced protein 44-like | 0.0224264 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0224183 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0224045 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0221989 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0220378 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0219186 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0218503 |
| PLK2 | polo-like kinase 2 | 0.0216048 |
| RNF213 | ring finger protein 213 | 0.0212041 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0208133 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0205466 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0204982 |
| FLNA | filamin A, alpha | 0.0204837 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0200181 |
| CAPRIN2 | caprin family member 2 | 0.0199633 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0199555 |
| RIN2 | Ras and Rab interactor 2 | 0.0196695 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0195955 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0195953 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0195621 |
| IL6ST | interleukin 6 signal transducer | 0.0195355 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0194696 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0194368 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0189179 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0188132 |
| SVIL | supervillin | 0.0184224 |
| OSMR | oncostatin M receptor | 0.0181232 |
| MUC16 | mucin 16, cell surface associated | 0.0177599 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0177157 |
| FAM3C | family with sequence similarity 3, member C | 0.0175811 |
| EGR1 | early growth response 1 | 0.0175085 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0174442 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0173393 |
| ITGA6 | integrin, alpha 6 | 0.0172733 |
| CFB | complement factor B | 0.0171412 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0171073 |
| CPM | carboxypeptidase M | 0.0170337 |
| BCL2L1 | BCL2-like 1 | 0.016714 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0166886 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0166071 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0165362 |
| PMP22 | peripheral myelin protein 22 | 0.0165214 |
| SHROOM3 | shroom family member 3 | 0.0164602 |
| TMC5 | transmembrane channel-like 5 | 0.0164437 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0162825 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0162652 |
| AREG | amphiregulin | 0.0162482 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0161816 |
| MEIS1 | Meis homeobox 1 | 0.0160556 |
| MCL1 | myeloid cell leukemia 1 | 0.0160222 |
| LIPH | lipase, member H | 0.0159876 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0159212 |
| BPTF | bromodomain PHD finger transcription factor | 0.0156124 |
| VMP1 | vacuole membrane protein 1 | 0.0154784 |
| GPHN | gephyrin | 0.0154448 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0153263 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.19059 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.148427 |
| DTNA | dystrobrevin, alpha | -0.147346 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112954 |
| NDRG1 | N-myc downstream regulated 1 | -0.109271 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.103706 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.090171 |
| MMP7 | matrix metallopeptidase 7 | -0.0875635 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0853707 |
| FLNB | filamin B, beta | -0.0839128 |
| TMSB10 | thymosin beta 10 | -0.0822041 |
| ANXA2 | annexin A2 | -0.0748392 |
| POTEF | POTE ankyrin domain family, member F | -0.0728166 |
| LAMC2 | laminin, gamma 2 | -0.0721894 |
| PTMA | prothymosin, alpha | -0.0719642 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0669401 |
| PGK1 | phosphoglycerate kinase 1 | -0.0660016 |
| LAMB3 | laminin, beta 3 | -0.0650953 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0648874 |
| CCNY | cyclin Y | -0.0646781 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.064487 |
| FAM13A | family with sequence similarity 13, member A | -0.0630165 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0624986 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0622201 |
| PKM | pyruvate kinase, muscle | -0.0610233 |
| HMGA1 | high mobility group AT-hook 1 | -0.0609249 |
| ACTG1 | actin gamma 1 | -0.0561988 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.056105 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0556688 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.055164 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0550011 |
| ACTN4 | actinin, alpha 4 | -0.0546897 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0541461 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0522237 |
| MEF2A | myocyte enhancer factor 2A | -0.0513569 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0512584 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0505636 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0499926 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0497672 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0493664 |
| SPAG9 | sperm associated antigen 9 | -0.0491911 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0476689 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0475045 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0465143 |
| MYOF | myoferlin | -0.0463353 |
| TMSB4X | thymosin beta 4, X-linked | -0.0448873 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0443789 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0440551 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0437672 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0420265 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0420116 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0419711 |
| SRP54 | signal recognition particle 54kDa | -0.0413651 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0413468 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0411362 |
| LDHA | lactate dehydrogenase A | -0.0410534 |
| SEC24A | SEC24 family member A | -0.0407214 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0400088 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0398042 |
| HELZ | helicase with zinc finger | -0.0393729 |
| PFKP | phosphofructokinase, platelet | -0.0393498 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0388902 |
| LASP1 | LIM and SH3 protein 1 | -0.0385732 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0384288 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0383482 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0379065 |
| CANX | calnexin | -0.0376173 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0375411 |
| CMIP | c-Maf inducing protein | -0.0373378 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0372188 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0369288 |
| GNAS | GNAS complex locus | -0.0361895 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0359043 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0352555 |
| ITGB4 | integrin, beta 4 | -0.0352029 |
| RTN4 | reticulon 4 | -0.0347039 |
| ABI1 | abl-interactor 1 | -0.0344084 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0341665 |
| RRBP1 | ribosome binding protein 1 | -0.0340639 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0340176 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.033966 |
| JUP | junction plakoglobin | -0.0335442 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0335335 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0333557 |
| TFG | TRK-fused gene | -0.0332079 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0331449 |
| RPL23 | ribosomal protein L23 | -0.0327234 |
| RUNX1 | runt-related transcription factor 1 | -0.032488 |
| MAP1B | microtubule-associated protein 1B | -0.0320267 |
| MORF4L2 | mortality factor 4 like 2 | -0.0315771 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0315743 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0314604 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0314389 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0312783 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.031015 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.030965 |
| PLS3 | plastin 3 | -0.0307435 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0307308 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0304286 |
| HLA-B | major histocompatibility complex, class I, B | -0.0302706 |
