| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.191148 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.133059 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.130693 |
| RUNX1 | runt-related transcription factor 1 | 0.114929 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.107409 |
| MYO1E | myosin IE | 0.100372 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0838893 |
| ITGA6 | integrin, alpha 6 | 0.0773574 |
| EZR | ezrin | 0.0734004 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0688074 |
| MUC13 | mucin 13, cell surface associated | 0.0638446 |
| LCN2 | lipocalin 2 | 0.0619929 |
| DSPP | dentin sialophosphoprotein | 0.0590168 |
| ANXA2 | annexin A2 | 0.0575079 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0572671 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0548435 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0509564 |
| STK24 | serine/threonine kinase 24 | 0.0480899 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0453069 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.044062 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0438033 |
| ATP11A | ATPase, class VI, type 11A | 0.0436485 |
| INTS6 | integrator complex subunit 6 | 0.0430486 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0429951 |
| RNF43 | ring finger protein 43 | 0.0410856 |
| NEBL | nebulette | 0.0400641 |
| MX1 | MX dynamin-like GTPase 1 | 0.0388283 |
| APP | amyloid beta (A4) precursor protein | 0.0382781 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0379402 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0377532 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0370186 |
| AREG | amphiregulin | 0.0364052 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0351503 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0350076 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0345528 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0344349 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0340938 |
| YAP1 | Yes-associated protein 1 | 0.0339355 |
| SPATA13 | spermatogenesis associated 13 | 0.0336559 |
| SQSTM1 | sequestosome 1 | 0.0336073 |
| FAT1 | FAT atypical cadherin 1 | 0.0334663 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0327427 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0318562 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0308935 |
| AOPEP | aminopeptidase O (putative) | 0.0308851 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0307382 |
| DST | dystonin | 0.0299999 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0299031 |
| PRSS3 | protease, serine, 3 | 0.0294608 |
| MEIS2 | Meis homeobox 2 | 0.0293059 |
| CTBP2 | C-terminal binding protein 2 | 0.0292287 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0291805 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0283284 |
| ACTN4 | actinin, alpha 4 | 0.0281723 |
| TC2N | tandem C2 domains, nuclear | 0.028128 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0278093 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0278063 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0274596 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0272639 |
| EPHB2 | EPH receptor B2 | 0.0270868 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0265754 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0261652 |
| VCL | vinculin | 0.0261438 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0259058 |
| DUSP16 | dual specificity phosphatase 16 | 0.0258436 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0257205 |
| SLC2A12 | solute carrier family 2 (facilitated glucose transporter), member 12 | 0.0256556 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0254017 |
| MCL1 | myeloid cell leukemia 1 | 0.0249994 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0249855 |
| ATP10B | ATPase, class V, type 10B | 0.0245777 |
| DPP4 | dipeptidyl-peptidase 4 | 0.024283 |
| EFNB2 | ephrin-B2 | 0.0241159 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.023972 |
| KIAA1217 | KIAA1217 | 0.0239024 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0237569 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0237446 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0233776 |
| TPM4 | tropomyosin 4 | 0.0228966 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0227894 |
| NCALD | neurocalcin delta | 0.0227623 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0226663 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0224141 |
| EFNA5 | ephrin-A5 | 0.0224111 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0222819 |
| CTTN | cortactin | 0.0222232 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0222161 |
| SUSD1 | sushi domain containing 1 | 0.0220772 |
| EHF | ets homologous factor | 0.0220266 |
| ADD3 | adducin 3 (gamma) | 0.0219531 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0218184 |
| MYO5B | myosin VB | 0.0217522 |
| CCNL1 | cyclin L1 | 0.0216454 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0216005 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0215912 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0215566 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0215399 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0214079 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0213519 |
| MUC20 | mucin 20, cell surface associated | 0.021336 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.197277 |
| LYZ | lysozyme | -0.128886 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.126105 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.109228 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.101278 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0900048 |
| EGR1 | early growth response 1 | -0.07911 |
| PERP | PERP, TP53 apoptosis effector | -0.0782304 |
| ERBIN | erbb2 interacting protein | -0.0767332 |
| NPSR1 | neuropeptide S receptor 1 | -0.0760373 |
| PTMA | prothymosin, alpha | -0.0753806 |
| TXNIP | thioredoxin interacting protein | -0.067439 |
| HLA-B | major histocompatibility complex, class I, B | -0.0614058 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.059463 |
| NDRG1 | N-myc downstream regulated 1 | -0.0589969 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0566021 |
| AHI1 | Abelson helper integration site 1 | -0.0537659 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0505939 |
| RPL35A | ribosomal protein L35a | -0.0501706 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0494157 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0489256 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0478087 |
| EFHD2 | EF-hand domain family, member D2 | -0.0453435 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0441089 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.04397 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0431857 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0405078 |
| DSCAM | Down syndrome cell adhesion molecule | -0.03997 |
| PGK1 | phosphoglycerate kinase 1 | -0.0388597 |
| KRT19 | keratin 19, type I | -0.038522 |
| TMSB10 | thymosin beta 10 | -0.0382027 |
| POTEF | POTE ankyrin domain family, member F | -0.037741 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0375139 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0368098 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0360818 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.036049 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0356542 |
| S100A6 | S100 calcium binding protein A6 | -0.0355963 |
| HLA-A | major histocompatibility complex, class I, A | -0.0354825 |
| RPL34 | ribosomal protein L34 | -0.0348898 |
| HMGB1 | high mobility group box 1 | -0.0344861 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0343887 |
| ZNF292 | zinc finger protein 292 | -0.0342926 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0338253 |
| LIMA1 | LIM domain and actin binding 1 | -0.033797 |
| FNIP1 | folliculin interacting protein 1 | -0.0334585 |
| ZNF148 | zinc finger protein 148 | -0.0334214 |
| PHF3 | PHD finger protein 3 | -0.033106 |
| CTSD | cathepsin D | -0.0329394 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.032892 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0328472 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0326033 |
| ANXA4 | annexin A4 | -0.0312825 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.031217 |
| PKM | pyruvate kinase, muscle | -0.0310049 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0309243 |
| PLIN2 | perilipin 2 | -0.0300442 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0299447 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.029683 |
| FTL | ferritin, light polypeptide | -0.0292807 |
| RNF149 | ring finger protein 149 | -0.0285912 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0281946 |
| RBM25 | RNA binding motif protein 25 | -0.0281888 |
| KLHL24 | kelch-like family member 24 | -0.0281872 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.028165 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0281429 |
| DIAPH1 | diaphanous-related formin 1 | -0.0280729 |
| S100A11 | S100 calcium binding protein A11 | -0.0280263 |
| TAOK3 | TAO kinase 3 | -0.0272574 |
| PTEN | phosphatase and tensin homolog | -0.026871 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0268622 |
| RPS24 | ribosomal protein S24 | -0.0265109 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0263428 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0256253 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0252514 |
| PMP22 | peripheral myelin protein 22 | -0.024876 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0243806 |
| ZNF395 | zinc finger protein 395 | -0.0243772 |
| NCKAP5 | NCK-associated protein 5 | -0.0243634 |
| RPS19 | ribosomal protein S19 | -0.0242971 |
| WASF2 | WAS protein family, member 2 | -0.0241239 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.023977 |
| UFM1 | ubiquitin-fold modifier 1 | -0.023802 |
| HLA-C | major histocompatibility complex, class I, C | -0.0237005 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0236341 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0235775 |
| SERF2 | small EDRK-rich factor 2 | -0.0234296 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0231576 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0231394 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0230824 |
| DEK | DEK proto-oncogene | -0.0227757 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0225778 |
| MMP7 | matrix metallopeptidase 7 | -0.0225689 |
| NBR1 | neighbor of BRCA1 gene 1 | -0.0224623 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0224517 |
| GNAS | GNAS complex locus | -0.0221688 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0220809 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.021975 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0218421 |
| RPS23 | ribosomal protein S23 | -0.0218396 |
