| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.197549 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.173777 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0912546 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0590318 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0445432 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0415744 |
| NLGN1 | neuroligin 1 | 0.0400433 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0347315 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0342553 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0328909 |
| CD44 | CD44 molecule (Indian blood group) | 0.0316715 |
| MKI67 | marker of proliferation Ki-67 | 0.0313098 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0305964 |
| ASPH | aspartate beta-hydroxylase | 0.0296885 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0290668 |
| VCL | vinculin | 0.0281327 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0268837 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0267554 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0252758 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0234884 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0228048 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0227899 |
| WWOX | WW domain containing oxidoreductase | 0.0225454 |
| PTK2 | protein tyrosine kinase 2 | 0.022375 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0216172 |
| FGF13 | fibroblast growth factor 13 | 0.0215025 |
| SETBP1 | SET binding protein 1 | 0.0212298 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0197113 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | 0.0193747 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0191629 |
| PLEC | plectin | 0.0191357 |
| ECE1 | endothelin converting enzyme 1 | 0.0188745 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0185616 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0184825 |
| WLS | wntless Wnt ligand secretion mediator | 0.0184559 |
| AUTS2 | autism susceptibility candidate 2 | 0.0182721 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.017936 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0178125 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0177735 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0177187 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | 0.0175722 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0175662 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0173157 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0169158 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0168714 |
| AHR | aryl hydrocarbon receptor | 0.0168632 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0168456 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.016841 |
| ITGA6 | integrin, alpha 6 | 0.016792 |
| RIGI | RNA sensor RIG-I | 0.0164498 |
| NRXN3 | neurexin 3 | 0.0163336 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0162951 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0159208 |
| EMP1 | epithelial membrane protein 1 | 0.0158634 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0157527 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0156035 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0155643 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0153104 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0152684 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0152676 |
| OSMR | oncostatin M receptor | 0.0149148 |
| NAV2 | neuron navigator 2 | 0.0147869 |
| IGF2 | insulin-like growth factor 2 | 0.0147265 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0146575 |
| SVIL | supervillin | 0.0142615 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0142348 |
| FLNA | filamin A, alpha | 0.0141086 |
| FANCI | Fanconi anemia, complementation group I | 0.0137051 |
| C3 | complement component 3 | 0.0135331 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0134382 |
| CEP128 | centrosomal protein 128kDa | 0.0133401 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0133166 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0131572 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0130497 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0129545 |
| UBC | ubiquitin C | 0.0129518 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0129068 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0128182 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0127867 |
| CTSB | cathepsin B | 0.0127797 |
| CENPF | centromere protein F, 350/400kDa | 0.0127771 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.012767 |
| JUN | jun proto-oncogene | 0.012677 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0126578 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0126452 |
| DIAPH2 | diaphanous-related formin 2 | 0.0126285 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0123405 |
| STK24 | serine/threonine kinase 24 | 0.0122706 |
| CEP112 | centrosomal protein 112kDa | 0.0122651 |
| HMGA2 | high mobility group AT-hook 2 | 0.0121282 |
| FHL2 | four and a half LIM domains 2 | 0.0121023 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0119018 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.0117413 |
| EGR1 | early growth response 1 | 0.0117209 |
| H1-4 | H1.4 linker histone, cluster member | 0.0117167 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.011676 |
| PRSS23 | protease, serine, 23 | 0.0116465 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0115062 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0113952 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0113602 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.224782 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.182011 |
| NDRG1 | N-myc downstream regulated 1 | -0.163826 |
| TMSB10 | thymosin beta 10 | -0.10805 |
| EGFR | epidermal growth factor receptor | -0.105543 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0951924 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0846828 |
| VIM | vimentin | -0.083651 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0827058 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0775848 |
| SBF2 | SET binding factor 2 | -0.0750067 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0720913 |
| INHBA | inhibin, beta A | -0.0719081 |
| CADM1 | cell adhesion molecule 1 | -0.0707936 |
| GOLGA4 | golgin A4 | -0.0678959 |
| GOLGB1 | golgin B1 | -0.0666126 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0647613 |
| CANX | calnexin | -0.0646075 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0623862 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0585412 |
| COG5 | component of oligomeric golgi complex 5 | -0.0583699 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0579895 |
| PTMA | prothymosin, alpha | -0.0572936 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0563773 |
| COPA | coatomer protein complex, subunit alpha | -0.0559689 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0554659 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0549568 |
| SEC24D | SEC24 family member D | -0.0548268 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0538837 |
| CALD1 | caldesmon 1 | -0.0533737 |
| SCFD2 | sec1 family domain containing 2 | -0.0530857 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0522175 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.051524 |
| FTL | ferritin, light polypeptide | -0.0514341 |
| SRP54 | signal recognition particle 54kDa | -0.0513188 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0506284 |
| GDF15 | growth differentiation factor 15 | -0.0500011 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0484992 |
| FNIP1 | folliculin interacting protein 1 | -0.0470237 |
| HDLBP | high density lipoprotein binding protein | -0.0467655 |
| HDAC9 | histone deacetylase 9 | -0.0464792 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0452775 |
| TNNC1 | troponin C type 1 (slow) | -0.0450784 |
| STC1 | stanniocalcin 1 | -0.044773 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0444789 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0443272 |
| MORF4L2 | mortality factor 4 like 2 | -0.0441141 |
| CDK13 | cyclin-dependent kinase 13 | -0.0441012 |
| ANKRD11 | ankyrin repeat domain 11 | -0.042485 |
| MT2A | metallothionein 2A | -0.0424331 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0421898 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0418733 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0409663 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0405749 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0401173 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0396423 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0392971 |
| USP36 | ubiquitin specific peptidase 36 | -0.0390872 |
| SUCO | SUN domain containing ossification factor | -0.038663 |
| RTN4 | reticulon 4 | -0.0385223 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0370759 |
| CLTC | clathrin, heavy chain (Hc) | -0.0366181 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0362443 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0357644 |
| NBEAL1 | neurobeachin-like 1 | -0.0351259 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0350882 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0350473 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0350412 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0349588 |
| LDHA | lactate dehydrogenase A | -0.0347653 |
| GNAS | GNAS complex locus | -0.0347456 |
| LRRC49 | leucine rich repeat containing 49 | -0.0345217 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0344149 |
| HM13 | histocompatibility (minor) 13 | -0.034079 |
| GPR173 | G protein-coupled receptor 173 | -0.0340032 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0339918 |
| MAP4 | microtubule-associated protein 4 | -0.0331675 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0331577 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0329403 |
| RNF216 | ring finger protein 216 | -0.032016 |
| CD109 | CD109 molecule | -0.0316967 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.031678 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0314072 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0313412 |
| CLINT1 | clathrin interactor 1 | -0.0313176 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0311861 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0310574 |
| MMP12 | matrix metallopeptidase 12 | -0.0308874 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0308369 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0301817 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0300828 |
| PMM2 | phosphomannomutase 2 | -0.0300195 |
| LOX | lysyl oxidase | -0.0299394 |
| TMEM39A | transmembrane protein 39A | -0.0298467 |
| GLG1 | golgi glycoprotein 1 | -0.0295059 |
| RRBP1 | ribosome binding protein 1 | -0.0294285 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0294048 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0293578 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0288689 |
| ZNF395 | zinc finger protein 395 | -0.0288289 |
