| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNA | filamin A, alpha | 0.106072 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.102262 |
| MKI67 | marker of proliferation Ki-67 | 0.0748412 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0731171 |
| SVIL | supervillin | 0.0645634 |
| LAMC2 | laminin, gamma 2 | 0.0542017 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0527806 |
| CD44 | CD44 molecule (Indian blood group) | 0.0494095 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0465049 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0445571 |
| PAX8 | paired box 8 | 0.0429706 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0391586 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0388851 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0386998 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0377121 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0363933 |
| HSPA8 | heat shock 70kDa protein 8 | 0.03502 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0346296 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0326751 |
| MMS22L | MMS22-like, DNA repair protein | 0.0316905 |
| TXNRD1 | thioredoxin reductase 1 | 0.0312767 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0312207 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0310373 |
| H1-4 | H1.4 linker histone, cluster member | 0.0309689 |
| ITGA6 | integrin, alpha 6 | 0.0302942 |
| INTS6 | integrator complex subunit 6 | 0.0301644 |
| VMP1 | vacuole membrane protein 1 | 0.0298487 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0282632 |
| TPM4 | tropomyosin 4 | 0.0281673 |
| DSPP | dentin sialophosphoprotein | 0.0281569 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0281168 |
| RPS27A | ribosomal protein S27a | 0.0279626 |
| FAT1 | FAT atypical cadherin 1 | 0.0278003 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0273845 |
| IRF1 | interferon regulatory factor 1 | 0.0271774 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0271278 |
| WWC1 | WW and C2 domain containing 1 | 0.026716 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0266568 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0266545 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0263649 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0258713 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0257927 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0257451 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0256983 |
| RPL38 | ribosomal protein L38 | 0.0256488 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0253349 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0253132 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0249512 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0249181 |
| VCL | vinculin | 0.0249121 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0246928 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0246794 |
| ATXN1 | ataxin 1 | 0.0244494 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.024377 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0238864 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0237154 |
| RPS25 | ribosomal protein S25 | 0.0236854 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0234852 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0228461 |
| RAD51B | RAD51 paralog B | 0.0226401 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0225026 |
| BRD2 | bromodomain containing 2 | 0.0224625 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0224157 |
| SKIL | SKI-like proto-oncogene | 0.0223858 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0221917 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0219027 |
| RPS29 | ribosomal protein S29 | 0.0217113 |
| LAMA4 | laminin, alpha 4 | 0.0214511 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0214484 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0213744 |
| SSH2 | slingshot protein phosphatase 2 | 0.0213578 |
| ENO1 | enolase 1, (alpha) | 0.0213192 |
| RPL37A | ribosomal protein L37a | 0.0211736 |
| SET | SET nuclear proto-oncogene | 0.0210431 |
| ITGB6 | integrin, beta 6 | 0.0207741 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0206808 |
| DMXL1 | Dmx-like 1 | 0.0205269 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0203802 |
| MACROD2 | MACRO domain containing 2 | 0.0203412 |
| CAB39 | calcium binding protein 39 | 0.0202139 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0201487 |
| VIM | vimentin | 0.0201055 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0200441 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0200273 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.01994 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0196208 |
| ITGAV | integrin, alpha V | 0.0196127 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0195975 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0195899 |
| PLEC | plectin | 0.019511 |
| RANBP17 | RAN binding protein 17 | 0.0194737 |
| HMGA2 | high mobility group AT-hook 2 | 0.0194467 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0194245 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0193974 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0193374 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0193287 |
| JUN | jun proto-oncogene | 0.0190893 |
| KRT86 | keratin 86, type II | 0.0190778 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0188632 |
| AATF | apoptosis antagonizing transcription factor | 0.0186387 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.225951 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.191172 |
| FNDC3B | fibronectin type III domain containing 3B | -0.131583 |
| NDRG1 | N-myc downstream regulated 1 | -0.104087 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0962775 |
| LDHA | lactate dehydrogenase A | -0.094112 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0825589 |
| GOLGA4 | golgin A4 | -0.0767162 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0703398 |
| TMSB10 | thymosin beta 10 | -0.0654758 |
| HELZ | helicase with zinc finger | -0.0653227 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0613619 |
| HMGA1 | high mobility group AT-hook 1 | -0.0600398 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0589159 |
| ZNF292 | zinc finger protein 292 | -0.0587601 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0574451 |
| ANXA2 | annexin A2 | -0.0558363 |
| CANX | calnexin | -0.0542397 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0531459 |
| KRT7 | keratin 7, type II | -0.0520091 |
| RNF145 | ring finger protein 145 | -0.0513461 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0512646 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0492806 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0490709 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.048498 |
| POTEF | POTE ankyrin domain family, member F | -0.0474577 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0470823 |
| B2M | beta-2-microglobulin | -0.0451168 |
| GNAS | GNAS complex locus | -0.0437335 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0437062 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0435014 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.043214 |
| SEPTIN7 | septin 7 | -0.0431091 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0430683 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0424848 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0422812 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0422789 |
| SBF2 | SET binding factor 2 | -0.041441 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0412157 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0406549 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0403436 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0401425 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0396972 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0396068 |
| RPLP0 | ribosomal protein, large, P0 | -0.0395335 |
| SEC24D | SEC24 family member D | -0.0395328 |
| FNBP1L | formin binding protein 1-like | -0.0393253 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0392942 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0391835 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0390585 |
| NF1 | neurofibromin 1 | -0.0387454 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0386353 |
| BBX | bobby sox homolog (Drosophila) | -0.0381656 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0377234 |
| RPS4X | ribosomal protein S4, X-linked | -0.0376759 |
| YBX1 | Y box binding protein 1 | -0.0372785 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.037245 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0371183 |
| INSIG2 | insulin induced gene 2 | -0.0365289 |
| PGK1 | phosphoglycerate kinase 1 | -0.0364868 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0362847 |
| FTL | ferritin, light polypeptide | -0.0359503 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0357176 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0355233 |
| TKT | transketolase | -0.0352403 |
| TPD52 | tumor protein D52 | -0.0351229 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0350022 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.034251 |
| FNIP1 | folliculin interacting protein 1 | -0.0342375 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0342179 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0338013 |
| AHNAK | AHNAK nucleoprotein | -0.0337835 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.033733 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0337235 |
| FAM162A | family with sequence similarity 162, member A | -0.0335543 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0330067 |
| RPL23 | ribosomal protein L23 | -0.0327806 |
| IRS2 | insulin receptor substrate 2 | -0.0325648 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0318263 |
| CAPNS1 | calpain, small subunit 1 | -0.0318111 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.031803 |
| CLINT1 | clathrin interactor 1 | -0.031577 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0314827 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0314047 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0311648 |
| TUBB | tubulin, beta class I | -0.0311408 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0309489 |
| HDLBP | high density lipoprotein binding protein | -0.0308755 |
| ACTN4 | actinin, alpha 4 | -0.0307324 |
| MATR3 | matrin 3 | -0.0305699 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0305136 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0303026 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0300869 |
| PRRC2B | proline-rich coiled-coil 2B | -0.030077 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0296202 |
| KLF6 | Kruppel-like factor 6 | -0.0294462 |
| RPL32 | ribosomal protein L32 | -0.0293682 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0293527 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0293505 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0293357 |
