| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.164538 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.124962 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0812648 |
| VCL | vinculin | 0.0793604 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0761764 |
| DST | dystonin | 0.0740498 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0727499 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0713496 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0678424 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.057076 |
| FLNA | filamin A, alpha | 0.0569916 |
| MAP1B | microtubule-associated protein 1B | 0.054103 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0525988 |
| PLEC | plectin | 0.0492637 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0442689 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0433201 |
| MSN | moesin | 0.0429053 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0384729 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0372712 |
| CLIC4 | chloride intracellular channel 4 | 0.0372659 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0371666 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0362546 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0355295 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0350387 |
| RRM2 | ribonucleotide reductase M2 | 0.0319775 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0318764 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.031787 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0311195 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.028481 |
| NAV1 | neuron navigator 1 | 0.0280092 |
| ACTN1 | actinin, alpha 1 | 0.0273741 |
| JAG1 | jagged 1 | 0.0264328 |
| RAD51B | RAD51 paralog B | 0.0263976 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0262168 |
| SMC1A | structural maintenance of chromosomes 1A | 0.024123 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0241032 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0233703 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0233058 |
| CAPRIN2 | caprin family member 2 | 0.023252 |
| WWOX | WW domain containing oxidoreductase | 0.0229678 |
| MKI67 | marker of proliferation Ki-67 | 0.0227737 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0226812 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0223951 |
| GLIS3 | GLIS family zinc finger 3 | 0.022315 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0223046 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0220499 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0220103 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0219963 |
| EGFR | epidermal growth factor receptor | 0.0219945 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0219397 |
| TPM3 | tropomyosin 3 | 0.0217579 |
| CD82 | CD82 molecule | 0.0215177 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0214468 |
| VMP1 | vacuole membrane protein 1 | 0.0213533 |
| RCOR1 | REST corepressor 1 | 0.0210781 |
| SVIL | supervillin | 0.0209851 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0208402 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0201662 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0196154 |
| FHIT | fragile histidine triad | 0.0194863 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0190709 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0188242 |
| MTAP | methylthioadenosine phosphorylase | 0.0184007 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0181207 |
| EHBP1 | EH domain binding protein 1 | 0.0180163 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0177854 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | 0.0173475 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0172916 |
| KLF12 | Kruppel-like factor 12 | 0.0172018 |
| NRP1 | neuropilin 1 | 0.0170769 |
| DIAPH3 | diaphanous-related formin 3 | 0.017065 |
| ACTG1 | actin gamma 1 | 0.0169722 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0169041 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0168251 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0166989 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.01666 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0165129 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0164485 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.0162207 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0161716 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0161138 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0160622 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0159223 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0158937 |
| TPI1 | triosephosphate isomerase 1 | 0.0158817 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0158127 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0158111 |
| DSPP | dentin sialophosphoprotein | 0.0156117 |
| LMNA | lamin A/C | 0.015579 |
| FERMT2 | fermitin family member 2 | 0.0154301 |
| EXOC4 | exocyst complex component 4 | 0.0152564 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0151949 |
| SETBP1 | SET binding protein 1 | 0.0150992 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0150707 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0150637 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0149336 |
| SUMF1 | sulfatase modifying factor 1 | 0.014915 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0148987 |
| EGR1 | early growth response 1 | 0.0148423 |
| TGFB1 | transforming growth factor, beta 1 | 0.0145823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.30402 |
| VIM | vimentin | -0.204952 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.145903 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.134214 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.130645 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.12888 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127715 |
| NDRG1 | N-myc downstream regulated 1 | -0.123328 |
| MT2A | metallothionein 2A | -0.110719 |
| FN1 | fibronectin 1 | -0.110476 |
| CDH13 | cadherin 13 | -0.108355 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.108117 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.103592 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0978886 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0859507 |
| FAM13A | family with sequence similarity 13, member A | -0.0822408 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0728178 |
| PDE10A | phosphodiesterase 10A | -0.0727706 |
| STC1 | stanniocalcin 1 | -0.072185 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0721746 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0707144 |
| LDHA | lactate dehydrogenase A | -0.0667743 |
| DTNA | dystrobrevin, alpha | -0.0654788 |
| TMSB10 | thymosin beta 10 | -0.0624954 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0621234 |
| ASPH | aspartate beta-hydroxylase | -0.0611418 |
| COL5A1 | collagen, type V, alpha 1 | -0.0593267 |
| RPLP1 | ribosomal protein, large, P1 | -0.0592928 |
| CANX | calnexin | -0.0588588 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0587784 |
| PGK1 | phosphoglycerate kinase 1 | -0.0579421 |
| NGLY1 | N-glycanase 1 | -0.057492 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0559343 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0558993 |
| NAV2 | neuron navigator 2 | -0.0544771 |
| INHBA | inhibin, beta A | -0.0533629 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.052031 |
| PTMA | prothymosin, alpha | -0.0516501 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0509327 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0498519 |
| RPL35A | ribosomal protein L35a | -0.0493129 |
| RUNX1 | runt-related transcription factor 1 | -0.048131 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0480781 |
| LAMB3 | laminin, beta 3 | -0.0479762 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0466286 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0459007 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0456757 |
| TMEM165 | transmembrane protein 165 | -0.0450041 |
| RAB1A | RAB1A, member RAS oncogene family | -0.044499 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0444802 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0442392 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0437344 |
| OGA | O-GlcNAcase | -0.043551 |
| GOLGA4 | golgin A4 | -0.0428245 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0424112 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0422772 |
| LOX | lysyl oxidase | -0.042058 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0417039 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0406505 |
| HDLBP | high density lipoprotein binding protein | -0.0406263 |
| MMP12 | matrix metallopeptidase 12 | -0.0404394 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0398411 |
| WDR45B | WD repeat domain 45B | -0.0397249 |
| FNIP1 | folliculin interacting protein 1 | -0.0384008 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0375576 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0364958 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0362141 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0360605 |
| GNAS | GNAS complex locus | -0.0356912 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0355165 |
| RPS24 | ribosomal protein S24 | -0.0353415 |
| PCBP3 | poly(rC) binding protein 3 | -0.034506 |
| USP34 | ubiquitin specific peptidase 34 | -0.0338854 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0337611 |
| ZNF292 | zinc finger protein 292 | -0.0336131 |
| RPL34 | ribosomal protein L34 | -0.0335924 |
| HELZ | helicase with zinc finger | -0.0335622 |
| PTK2 | protein tyrosine kinase 2 | -0.0335395 |
| INSIG2 | insulin induced gene 2 | -0.0335386 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0328961 |
| ANXA2 | annexin A2 | -0.0326172 |
| CD109 | CD109 molecule | -0.0325106 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0320911 |
| CDCP1 | CUB domain containing protein 1 | -0.0320297 |
| RPS8 | ribosomal protein S8 | -0.0318983 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0318321 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0316487 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0314662 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0313651 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0309372 |
| FTL | ferritin, light polypeptide | -0.0307931 |
| RPS19 | ribosomal protein S19 | -0.0307897 |
| GLG1 | golgi glycoprotein 1 | -0.0304927 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0304022 |
| RNF24 | ring finger protein 24 | -0.0303362 |
| RPS27A | ribosomal protein S27a | -0.0300069 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0299445 |
| SEC24D | SEC24 family member D | -0.0296597 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0296117 |
| CCND1 | cyclin D1 | -0.0293234 |
