| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pyridoxine (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.110774 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.107173 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.101594 |
| PLK2 | polo-like kinase 2 | 0.0830225 |
| EZR | ezrin | 0.0781601 |
| FAT1 | FAT atypical cadherin 1 | 0.0685143 |
| PDZD8 | PDZ domain containing 8 | 0.0632461 |
| BCL2L1 | BCL2-like 1 | 0.0605037 |
| STK24 | serine/threonine kinase 24 | 0.0577495 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0531406 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0512221 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0509776 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0493472 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0492419 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0441243 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0439681 |
| NTN4 | netrin 4 | 0.0415739 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0411043 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0396588 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0393911 |
| MYO1E | myosin IE | 0.0388981 |
| WWC1 | WW and C2 domain containing 1 | 0.0388516 |
| AREG | amphiregulin | 0.0384233 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0383822 |
| EMP1 | epithelial membrane protein 1 | 0.0383103 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0382074 |
| SGMS2 | sphingomyelin synthase 2 | 0.0361551 |
| DSPP | dentin sialophosphoprotein | 0.0344647 |
| SMAD3 | SMAD family member 3 | 0.0336229 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0334187 |
| UBC | ubiquitin C | 0.033367 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.032684 |
| KRT18 | keratin 18, type I | 0.0322323 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0320348 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0319284 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0319213 |
| FLNB | filamin B, beta | 0.0318978 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0316584 |
| CCNYL1 | cyclin Y-like 1 | 0.0315749 |
| SEPTIN9 | septin 9 | 0.0310797 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0306 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0305898 |
| FLNA | filamin A, alpha | 0.029818 |
| CTBP2 | C-terminal binding protein 2 | 0.0294973 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0294404 |
| ANXA11 | annexin A11 | 0.0291821 |
| MYOF | myoferlin | 0.0282679 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.027603 |
| UTRN | utrophin | 0.027581 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0275758 |
| KIAA0232 | KIAA0232 | 0.0273987 |
| CD44 | CD44 molecule (Indian blood group) | 0.0264622 |
| TJP2 | tight junction protein 2 | 0.0264606 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0255638 |
| CTTN | cortactin | 0.0255116 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0252565 |
| PPL | periplakin | 0.0252327 |
| CLDN4 | claudin 4 | 0.0249405 |
| GSE1 | Gse1 coiled-coil protein | 0.0244978 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0233138 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0230735 |
| LIMA1 | LIM domain and actin binding 1 | 0.022784 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0227344 |
| PLEC | plectin | 0.0224473 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0224004 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0223463 |
| CLIC5 | chloride intracellular channel 5 | 0.0220984 |
| SET | SET nuclear proto-oncogene | 0.0218662 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0216994 |
| PDE10A | phosphodiesterase 10A | 0.0215077 |
| AXIN2 | axin 2 | 0.0210505 |
| RPL21 | ribosomal protein L21 | 0.020733 |
| MYEOV | myeloma overexpressed | 0.0197563 |
| ZFP36 | ZFP36 ring finger protein | 0.0196154 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0195235 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0195102 |
| LATS2 | large tumor suppressor kinase 2 | 0.0194369 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.0194229 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0194154 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.019227 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.0191169 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.018956 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.018813 |
| MKI67 | marker of proliferation Ki-67 | 0.0184928 |
| ATP10B | ATPase, class V, type 10B | 0.0184267 |
| RPL3 | ribosomal protein L3 | 0.0183724 |
| EREG | epiregulin | 0.0183705 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0182134 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.018198 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0181622 |
| KLF12 | Kruppel-like factor 12 | 0.0181433 |
| MSN | moesin | 0.0180325 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0178132 |
| FHL2 | four and a half LIM domains 2 | 0.0177711 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.017743 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0177395 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0177362 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.0175113 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa | 0.0174987 |
| TGFA | transforming growth factor, alpha | 0.0172869 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.211248 |
| NDRG1 | N-myc downstream regulated 1 | -0.190589 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.169613 |
| FNDC3B | fibronectin type III domain containing 3B | -0.134149 |
| FRY | furry homolog (Drosophila) | -0.128013 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.118601 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.114532 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.099616 |
| EXT1 | exostosin glycosyltransferase 1 | -0.097542 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0930545 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0889441 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0818076 |
| LDHA | lactate dehydrogenase A | -0.0789038 |
| AGR2 | anterior gradient 2 | -0.0775871 |
| RTN3 | reticulon 3 | -0.0775301 |
| HM13 | histocompatibility (minor) 13 | -0.072738 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0682109 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.067939 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0647927 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0647893 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0638591 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0623422 |
| RAD21 | RAD21 homolog (S. pombe) | -0.062006 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0617035 |
| ANXA2 | annexin A2 | -0.0603142 |
| INTS6 | integrator complex subunit 6 | -0.0586598 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0578481 |
| SQSTM1 | sequestosome 1 | -0.0564046 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0559045 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0541785 |
| ATXN1 | ataxin 1 | -0.0538713 |
| CANX | calnexin | -0.0524786 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0520286 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0519343 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0516061 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0510937 |
| MORF4L2 | mortality factor 4 like 2 | -0.0510543 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0508626 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0505569 |
| GOLGA4 | golgin A4 | -0.0501636 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0498773 |
| PRELID2 | PRELI domain containing 2 | -0.0497205 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0494713 |
| PTK2 | protein tyrosine kinase 2 | -0.0492386 |
| HDLBP | high density lipoprotein binding protein | -0.0486475 |
| RPLP1 | ribosomal protein, large, P1 | -0.0485909 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.048246 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0479397 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.047102 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0469423 |
| BBX | bobby sox homolog (Drosophila) | -0.046851 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0467654 |
| RPS24 | ribosomal protein S24 | -0.0463201 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0457869 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0457567 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0454349 |
| FNIP1 | folliculin interacting protein 1 | -0.0449535 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0443623 |
| ACTN4 | actinin, alpha 4 | -0.043888 |
| FOXO3 | forkhead box O3 | -0.0432963 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0431985 |
| NF1 | neurofibromin 1 | -0.0422849 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0418668 |
| DIAPH2 | diaphanous-related formin 2 | -0.041696 |
| RBM39 | RNA binding motif protein 39 | -0.0415102 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0411531 |
| PTMA | prothymosin, alpha | -0.041124 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0408587 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0407833 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0400486 |
| GNAS | GNAS complex locus | -0.0398678 |
| SEC24D | SEC24 family member D | -0.0398225 |
| RPL35A | ribosomal protein L35a | -0.0396671 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0393719 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0393658 |
| COG5 | component of oligomeric golgi complex 5 | -0.0390675 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0389773 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0389482 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0387678 |
| ZNF292 | zinc finger protein 292 | -0.0382584 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0382548 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.038012 |
| DGKH | diacylglycerol kinase, eta | -0.0380051 |
| CDK13 | cyclin-dependent kinase 13 | -0.0378947 |
| LNX2 | ligand of numb-protein X 2 | -0.0373525 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0372781 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0372463 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0369186 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0368135 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0367612 |
| HYOU1 | hypoxia up-regulated 1 | -0.036623 |
| CCNY | cyclin Y | -0.0364718 |
| SDC4 | syndecan 4 | -0.0361836 |
| EXOC4 | exocyst complex component 4 | -0.0361102 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0357869 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0356417 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0355883 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0354792 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0353158 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0351433 |
