| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.0618972 |
| NRG1 | neuregulin 1 | 0.054944 |
| TXNRD1 | thioredoxin reductase 1 | 0.0512067 |
| PLEC | plectin | 0.0502262 |
| EZR | ezrin | 0.0500637 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0462542 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0446662 |
| EMP1 | epithelial membrane protein 1 | 0.044474 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.039499 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0379188 |
| MKI67 | marker of proliferation Ki-67 | 0.0364792 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0352449 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0344194 |
| MYOF | myoferlin | 0.0329787 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0300666 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0292741 |
| AHNAK | AHNAK nucleoprotein | 0.0286872 |
| DSPP | dentin sialophosphoprotein | 0.0285039 |
| CD44 | CD44 molecule (Indian blood group) | 0.0275734 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0270234 |
| TPM3 | tropomyosin 3 | 0.0265549 |
| SLK | STE20-like kinase | 0.025655 |
| SLTM | SAFB-like, transcription modulator | 0.0256363 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0255656 |
| AOPEP | aminopeptidase O (putative) | 0.0254954 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.024655 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0245777 |
| FLNA | filamin A, alpha | 0.0240318 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0236559 |
| FOXP1 | forkhead box P1 | 0.0235324 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0234775 |
| EHF | ets homologous factor | 0.0230205 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.022928 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0226977 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0226579 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0218051 |
| JAG1 | jagged 1 | 0.0217557 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0215323 |
| H1-0 | H1.0 linker histone | 0.0211622 |
| PRELID2 | PRELI domain containing 2 | 0.0209888 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0208739 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0208442 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0198281 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0195605 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.019406 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0192681 |
| APP | amyloid beta (A4) precursor protein | 0.0189515 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0188606 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0187857 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.018563 |
| ANLN | anillin, actin binding protein | 0.0183596 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0180771 |
| EXOC6B | exocyst complex component 6B | 0.0179583 |
| FLNB | filamin B, beta | 0.0173989 |
| NEK7 | NIMA-related kinase 7 | 0.0170218 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0169501 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0167525 |
| MX1 | MX dynamin-like GTPase 1 | 0.016539 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.016387 |
| MEIS2 | Meis homeobox 2 | 0.0162985 |
| MSN | moesin | 0.0162984 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0161817 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0158539 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0155941 |
| BCL2L1 | BCL2-like 1 | 0.0154335 |
| ANXA11 | annexin A11 | 0.0153451 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.015319 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0153003 |
| FSTL1 | follistatin-like 1 | 0.0152968 |
| AFAP1 | actin filament associated protein 1 | 0.0152142 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0151499 |
| TGFA | transforming growth factor, alpha | 0.0150595 |
| MTAP | methylthioadenosine phosphorylase | 0.0150378 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0149445 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0146507 |
| PLK2 | polo-like kinase 2 | 0.0146142 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0145629 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0143296 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0142746 |
| STK4 | serine/threonine kinase 4 | 0.0140435 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0139786 |
| NCKAP1 | NCK-associated protein 1 | 0.0139376 |
| AFG2A | AFG2 AAA ATPase homolog A | 0.0138997 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0138771 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0137103 |
| VMP1 | vacuole membrane protein 1 | 0.0136789 |
| RIN2 | Ras and Rab interactor 2 | 0.0136584 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.013592 |
| MECOM | MDS1 and EVI1 complex locus | 0.0135444 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0134968 |
| PLEKHG5 | pleckstrin homology domain containing, family G (with RhoGef domain) member 5 | 0.0133518 |
| CAPRIN2 | caprin family member 2 | 0.0132886 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0130733 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0128008 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0127937 |
| OGA | O-GlcNAcase | 0.0127672 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0126515 |
| ANKRD36 | ankyrin repeat domain 36 | 0.012495 |
| DST | dystonin | 0.0123647 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0123082 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.235105 |
| RPS21 | ribosomal protein S21 | -0.127596 |
| MTSS1 | metastasis suppressor 1 | -0.119639 |
| B2M | beta-2-microglobulin | -0.116678 |
| TMSB10 | thymosin beta 10 | -0.107194 |
| NDRG1 | N-myc downstream regulated 1 | -0.104794 |
| RPS6 | ribosomal protein S6 | -0.101315 |
| MT2A | metallothionein 2A | -0.0989389 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0969408 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0948119 |
| PTMA | prothymosin, alpha | -0.0944537 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0938262 |
| RPS8 | ribosomal protein S8 | -0.0904518 |
| POTEF | POTE ankyrin domain family, member F | -0.0880428 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0870069 |
| STC1 | stanniocalcin 1 | -0.0828239 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0818246 |
| GNAS | GNAS complex locus | -0.0814432 |
| LDHA | lactate dehydrogenase A | -0.0811108 |
| RPS13 | ribosomal protein S13 | -0.0752842 |
| RPS19 | ribosomal protein S19 | -0.0742292 |
| RPLP1 | ribosomal protein, large, P1 | -0.0735376 |
| RPL11 | ribosomal protein L11 | -0.0710229 |
| INTS6 | integrator complex subunit 6 | -0.0670144 |
| RPLP2 | ribosomal protein, large, P2 | -0.0657309 |
| HLA-B | major histocompatibility complex, class I, B | -0.0654834 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0653944 |
| PDLIM5 | PDZ and LIM domain 5 | -0.065172 |
| IGF2 | insulin-like growth factor 2 | -0.0651504 |
| RPL23 | ribosomal protein L23 | -0.0633523 |
| RPL37 | ribosomal protein L37 | -0.0621053 |
| HM13 | histocompatibility (minor) 13 | -0.0616888 |
| RPL35A | ribosomal protein L35a | -0.0612879 |
| PLS3 | plastin 3 | -0.0609171 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0607508 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0591173 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0575141 |
| S100A10 | S100 calcium binding protein A10 | -0.0570884 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0568266 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0561835 |
| RPS25 | ribosomal protein S25 | -0.0559096 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0547275 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0546423 |
| S100A9 | S100 calcium binding protein A9 | -0.0541726 |
| RPS24 | ribosomal protein S24 | -0.0538642 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.051524 |
| RPL34 | ribosomal protein L34 | -0.049976 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0492318 |
| FTL | ferritin, light polypeptide | -0.0479871 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0458642 |
| HMGA1 | high mobility group AT-hook 1 | -0.0446362 |
| RPS23 | ribosomal protein S23 | -0.0441752 |
| RAI14 | retinoic acid induced 14 | -0.0430073 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0428975 |
| RPL8 | ribosomal protein L8 | -0.0424218 |
| RPS14 | ribosomal protein S14 | -0.0422285 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0422235 |
| EFHD2 | EF-hand domain family, member D2 | -0.0421938 |
| RPL31 | ribosomal protein L31 | -0.0420207 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0412119 |
| RPL5 | ribosomal protein L5 | -0.0411855 |
| S100A11 | S100 calcium binding protein A11 | -0.0411641 |
| RPL37A | ribosomal protein L37a | -0.041071 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0409968 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0407367 |
| RPL27A | ribosomal protein L27a | -0.0403112 |
| LMNA | lamin A/C | -0.0402612 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0397579 |
| RPL9 | ribosomal protein L9 | -0.039622 |
| KRT17 | keratin 17, type I | -0.0394006 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0393866 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0393035 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0392736 |
| RPS3 | ribosomal protein S3 | -0.0390035 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0388786 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0388302 |
| TAGLN2 | transgelin 2 | -0.038659 |
| RPS27 | ribosomal protein S27 | -0.0385808 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0377056 |
| RPL30 | ribosomal protein L30 | -0.03754 |
| S100A2 | S100 calcium binding protein A2 | -0.0371087 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0364366 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0362707 |
| RPL12 | ribosomal protein L12 | -0.0361823 |
| GOLGA4 | golgin A4 | -0.0361273 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0354653 |
| PALLD | palladin, cytoskeletal associated protein | -0.0354626 |
| RPL28 | ribosomal protein L28 | -0.0353347 |
| RPL35 | ribosomal protein L35 | -0.0352074 |
| RPLP0 | ribosomal protein, large, P0 | -0.0349807 |
| RPS12 | ribosomal protein S12 | -0.0347078 |
| RPS29 | ribosomal protein S29 | -0.034662 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.034425 |
| RPL26 | ribosomal protein L26 | -0.0340714 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0339629 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0337398 |
| RPL19 | ribosomal protein L19 | -0.0335944 |
| S100A6 | S100 calcium binding protein A6 | -0.0329798 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0329445 |
| RPL36 | ribosomal protein L36 | -0.0329046 |
