| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pyridoxine (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.0719559 |
| FLNA | filamin A, alpha | 0.0657511 |
| NAV1 | neuron navigator 1 | 0.0496429 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0481186 |
| RAD51B | RAD51 paralog B | 0.0385046 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0374726 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0372691 |
| PRELID2 | PRELI domain containing 2 | 0.0358388 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.033735 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0334172 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0332801 |
| MSN | moesin | 0.0328291 |
| MCL1 | myeloid cell leukemia 1 | 0.0326638 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0319746 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0317057 |
| ATXN1 | ataxin 1 | 0.0303903 |
| PLEC | plectin | 0.0301112 |
| AEBP2 | AE binding protein 2 | 0.0290759 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0283782 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0283067 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0282904 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0278531 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0277185 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0255116 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0254934 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0241994 |
| RPL37A | ribosomal protein L37a | 0.0235134 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0227164 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0222613 |
| NABP1 | nucleic acid binding protein 1 | 0.0221986 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0221022 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0220819 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0220513 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0218874 |
| LRRC23 | leucine rich repeat containing 23 | 0.0217674 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0217486 |
| VMP1 | vacuole membrane protein 1 | 0.0217368 |
| ANO6 | anoctamin 6 | 0.0214915 |
| NLGN1 | neuroligin 1 | 0.0210482 |
| RPL31 | ribosomal protein L31 | 0.0210387 |
| FLNB | filamin B, beta | 0.0209129 |
| MYO9A | myosin IXA | 0.0208056 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0204823 |
| RCC1 | regulator of chromosome condensation 1 | 0.0200332 |
| HMGA2 | high mobility group AT-hook 2 | 0.0196698 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0196693 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0196029 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.019523 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0191481 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0191401 |
| METTL15 | methyltransferase like 15 | 0.0188174 |
| ENO1 | enolase 1, (alpha) | 0.0187371 |
| PRKCA | protein kinase C, alpha | 0.0183418 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0182217 |
| TLN1 | talin 1 | 0.0181019 |
| RPS17 | ribosomal protein S17 | 0.0179453 |
| PDE10A | phosphodiesterase 10A | 0.0177752 |
| EXOC4 | exocyst complex component 4 | 0.0176274 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0176071 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0175389 |
| KLHL29 | kelch-like family member 29 | 0.0174107 |
| TEX14 | testis expressed 14 | 0.0171908 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0169088 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0168711 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0168012 |
| CMIP | c-Maf inducing protein | 0.0166518 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0165946 |
| DISC1 | disrupted in schizophrenia 1 | 0.0165585 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0163531 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0162714 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0162144 |
| SMYD3 | SET and MYND domain containing 3 | 0.0158569 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0157913 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0157792 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0157097 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0156238 |
| SETX | senataxin | 0.0155463 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0155412 |
| RPS29 | ribosomal protein S29 | 0.0155303 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0155235 |
| RPS25 | ribosomal protein S25 | 0.0154701 |
| UTRN | utrophin | 0.0154392 |
| RPL21 | ribosomal protein L21 | 0.0154107 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0153769 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0153063 |
| GOLGB1 | golgin B1 | 0.0152481 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0151799 |
| EGFR | epidermal growth factor receptor | 0.0151616 |
| ASPH | aspartate beta-hydroxylase | 0.015099 |
| WWOX | WW domain containing oxidoreductase | 0.0149848 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0146812 |
| RPS10 | ribosomal protein S10 | 0.0146494 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0146031 |
| EFNB2 | ephrin-B2 | 0.0145914 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0145544 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0145126 |
| RCOR1 | REST corepressor 1 | 0.0143912 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0141812 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0141437 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.014131 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.299925 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.210858 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205045 |
| LSAMP | limbic system-associated membrane protein | -0.155716 |
| DTNA | dystrobrevin, alpha | -0.148192 |
| MMP12 | matrix metallopeptidase 12 | -0.129135 |
| EXT1 | exostosin glycosyltransferase 1 | -0.122829 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0961905 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0801214 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0792317 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0760426 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0753196 |
| YBX3 | Y box binding protein 3 | -0.0744533 |
| ANXA2 | annexin A2 | -0.0693315 |
| RPS6 | ribosomal protein S6 | -0.0690475 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0666855 |
| TMSB10 | thymosin beta 10 | -0.0636762 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0629378 |
| LDHA | lactate dehydrogenase A | -0.058647 |
| PGK1 | phosphoglycerate kinase 1 | -0.0573159 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0569171 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0561689 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0559828 |
| CAVIN1 | caveolae associated protein 1 | -0.0553962 |
| CD109 | CD109 molecule | -0.0549568 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.054504 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0543475 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0541464 |
| RUNX1 | runt-related transcription factor 1 | -0.0528403 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0510515 |
| GPC6 | glypican 6 | -0.0506856 |
| HAS2 | hyaluronan synthase 2 | -0.0503583 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0503495 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0488377 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0483228 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0480243 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0479421 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0476998 |
| KLF6 | Kruppel-like factor 6 | -0.0472405 |
| RPLP0 | ribosomal protein, large, P0 | -0.0468713 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0467763 |
| SEPTIN7 | septin 7 | -0.0466922 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0465327 |
| NUP58 | nucleoporin 58 | -0.0464728 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.046012 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0448593 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0444825 |
| CDK17 | cyclin-dependent kinase 17 | -0.0443062 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0433414 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0426726 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0426681 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0424881 |
| PTK2 | protein tyrosine kinase 2 | -0.0422362 |
| RTN4 | reticulon 4 | -0.0416883 |
| RPL12 | ribosomal protein L12 | -0.0414589 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0412967 |
| LMAN1 | lectin, mannose-binding, 1 | -0.041242 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0406501 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0402538 |
| CSTB | cystatin B (stefin B) | -0.0400983 |
| WDR45B | WD repeat domain 45B | -0.0397484 |
| FTL | ferritin, light polypeptide | -0.0392647 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0388705 |
| LIMA1 | LIM domain and actin binding 1 | -0.0388551 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0387066 |
| SPAG9 | sperm associated antigen 9 | -0.038388 |
| TPM4 | tropomyosin 4 | -0.0381216 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0378254 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0377794 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0371243 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0370826 |
| RPL26 | ribosomal protein L26 | -0.0370117 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0369325 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.03672 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0366261 |
| PTMA | prothymosin, alpha | -0.0364773 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0363636 |
| CDH13 | cadherin 13 | -0.0361224 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0357328 |
| GNAS | GNAS complex locus | -0.035535 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0354274 |
| CDK6 | cyclin-dependent kinase 6 | -0.03537 |
| RBM39 | RNA binding motif protein 39 | -0.0351863 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0349988 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0348975 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.034791 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0344569 |
| RLF | rearranged L-myc fusion | -0.0344026 |
| JMJD1C | jumonji domain containing 1C | -0.0342442 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0338677 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0338321 |
| RPS24 | ribosomal protein S24 | -0.0334541 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0331634 |
| HMGA1 | high mobility group AT-hook 1 | -0.0329478 |
| USP3 | ubiquitin specific peptidase 3 | -0.0328319 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0327659 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0326477 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0325446 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0319671 |
| MAP4 | microtubule-associated protein 4 | -0.0317186 |
