| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pyridoxine (hydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.0777673 |
| TXNRD1 | thioredoxin reductase 1 | 0.069796 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0604998 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0558713 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0495915 |
| MUC13 | mucin 13, cell surface associated | 0.0408097 |
| RPL3 | ribosomal protein L3 | 0.0407712 |
| ITGA6 | integrin, alpha 6 | 0.0371074 |
| MX1 | MX dynamin-like GTPase 1 | 0.0365082 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0356369 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0337433 |
| SLTM | SAFB-like, transcription modulator | 0.0333654 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0328 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0327833 |
| LOC105378220 | macrophage receptor MARCO-like | 0.0327794 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.030812 |
| MKI67 | marker of proliferation Ki-67 | 0.0297979 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0297398 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0295491 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0282411 |
| PDZD8 | PDZ domain containing 8 | 0.028114 |
| PKP2 | plakophilin 2 | 0.0276052 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0275876 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0275441 |
| PCBP2 | poly(rC) binding protein 2 | 0.0272585 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0266113 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0259394 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.025432 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0243824 |
| TPM3 | tropomyosin 3 | 0.0241839 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0240992 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0240781 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0235038 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0229008 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0224762 |
| PCM1 | pericentriolar material 1 | 0.0215415 |
| WWOX | WW domain containing oxidoreductase | 0.0209335 |
| DST | dystonin | 0.0207627 |
| CCNL1 | cyclin L1 | 0.0206544 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0204472 |
| FLNA | filamin A, alpha | 0.0204193 |
| WWC1 | WW and C2 domain containing 1 | 0.0202345 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0202055 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0198934 |
| PCDHB16 | protocadherin beta 16 | 0.0197478 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0196977 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0196713 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0194034 |
| PHIP | pleckstrin homology domain interacting protein | 0.0192333 |
| NCKAP1 | NCK-associated protein 1 | 0.0191177 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0188032 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0187987 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0186033 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0181554 |
| KIF5B | kinesin family member 5B | 0.0180828 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0180264 |
| UBE3A | ubiquitin protein ligase E3A | 0.0177118 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0176363 |
| CENPF | centromere protein F, 350/400kDa | 0.0174064 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0170198 |
| ENO1 | enolase 1, (alpha) | 0.0170108 |
| ATP10B | ATPase, class V, type 10B | 0.0169071 |
| SET | SET nuclear proto-oncogene | 0.0167637 |
| AHR | aryl hydrocarbon receptor | 0.0166393 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.0165278 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0165148 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0162661 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.016232 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0162259 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0158828 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0158761 |
| UBC | ubiquitin C | 0.0156958 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0156461 |
| PNN | pinin, desmosome associated protein | 0.0156141 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0154916 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0153825 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0153684 |
| MT2A | metallothionein 2A | 0.0152308 |
| RNF43 | ring finger protein 43 | 0.0152099 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0151918 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.015058 |
| TLN2 | talin 2 | 0.0149434 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0148367 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0148195 |
| RPS3A | ribosomal protein S3A | 0.0146788 |
| ASPH | aspartate beta-hydroxylase | 0.0146289 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0146031 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.014344 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0142641 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0142571 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0141975 |
| TBK1 | TANK-binding kinase 1 | 0.0141254 |
| SLK | STE20-like kinase | 0.0140655 |
| EEA1 | early endosome antigen 1 | 0.0139989 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0138057 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0137742 |
| BCL2L1 | BCL2-like 1 | 0.0137705 |
| GOLM1 | golgi membrane protein 1 | 0.0135498 |
| USP47 | ubiquitin specific peptidase 47 | 0.0135215 |
| OXSR1 | oxidative stress responsive 1 | 0.0133824 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.265154 |
| RPLP1 | ribosomal protein, large, P1 | -0.194184 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.131909 |
| LMO7 | LIM domain 7 | -0.127958 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.127125 |
| RPL34 | ribosomal protein L34 | -0.11618 |
| RPL35A | ribosomal protein L35a | -0.109623 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100305 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0979903 |
| RPLP0 | ribosomal protein, large, P0 | -0.0978391 |
| ANXA2 | annexin A2 | -0.0959751 |
| TMSB10 | thymosin beta 10 | -0.0834227 |
| RPS8 | ribosomal protein S8 | -0.0831934 |
| LAMB3 | laminin, beta 3 | -0.0789649 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0783652 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0778483 |
| RPL26 | ribosomal protein L26 | -0.0747453 |
| RPS24 | ribosomal protein S24 | -0.0721941 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0691177 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0684611 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0681642 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0672608 |
| RPL31 | ribosomal protein L31 | -0.064874 |
| TSPAN8 | tetraspanin 8 | -0.064654 |
| RPS23 | ribosomal protein S23 | -0.0600031 |
| FRMD5 | FERM domain containing 5 | -0.0582957 |
| PALLD | palladin, cytoskeletal associated protein | -0.0577624 |
| INTS6 | integrator complex subunit 6 | -0.0576462 |
| RPS6 | ribosomal protein S6 | -0.0573152 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0567709 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0556875 |
| MYO1E | myosin IE | -0.055119 |
| RPS13 | ribosomal protein S13 | -0.0542316 |
| RPL27A | ribosomal protein L27a | -0.053972 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0537415 |
| PDLIM5 | PDZ and LIM domain 5 | -0.053467 |
| RPS25 | ribosomal protein S25 | -0.0534029 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0533004 |
| HLA-B | major histocompatibility complex, class I, B | -0.0530288 |
| RPS19 | ribosomal protein S19 | -0.0525495 |
| ACTN4 | actinin, alpha 4 | -0.0517779 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0510125 |
| RPS21 | ribosomal protein S21 | -0.0508848 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0505425 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0502957 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0492512 |
| NPSR1 | neuropeptide S receptor 1 | -0.0492111 |
| VCL | vinculin | -0.0489062 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0487097 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0482504 |
| HDLBP | high density lipoprotein binding protein | -0.0474755 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0470794 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0470573 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0469557 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0457789 |
| RPL9 | ribosomal protein L9 | -0.0455217 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.044516 |
| AGR2 | anterior gradient 2 | -0.0444496 |
| MCU | mitochondrial calcium uniporter | -0.0443629 |
| RPL37 | ribosomal protein L37 | -0.0436841 |
| LDHA | lactate dehydrogenase A | -0.0436297 |
| RPL11 | ribosomal protein L11 | -0.0433507 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0433389 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0432593 |
| FBXO11 | F-box protein 11 | -0.0427996 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0423926 |
| RPS20 | ribosomal protein S20 | -0.0420612 |
| FOXO3 | forkhead box O3 | -0.0412814 |
| AOPEP | aminopeptidase O (putative) | -0.0411721 |
| RPL37A | ribosomal protein L37a | -0.0411346 |
| MSI2 | musashi RNA-binding protein 2 | -0.0410168 |
| RPS16 | ribosomal protein S16 | -0.0397042 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0394954 |
| RPL12 | ribosomal protein L12 | -0.0389358 |
| PTMA | prothymosin, alpha | -0.0385917 |
| RRBP1 | ribosome binding protein 1 | -0.0379248 |
| RPS29 | ribosomal protein S29 | -0.0375015 |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | -0.0371035 |
| RPL30 | ribosomal protein L30 | -0.0369597 |
| MORF4L2 | mortality factor 4 like 2 | -0.0363817 |
| LRRC23 | leucine rich repeat containing 23 | -0.0361265 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0359344 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.035429 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0353933 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0348693 |
| UBAP2 | ubiquitin associated protein 2 | -0.0346669 |
| DENND1A | DENN/MADD domain containing 1A | -0.0346 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0344286 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0339998 |
| PERP | PERP, TP53 apoptosis effector | -0.0338751 |
| S100A6 | S100 calcium binding protein A6 | -0.0337044 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0335333 |
| RPL4 | ribosomal protein L4 | -0.0331026 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0328878 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0328462 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0327857 |
| RPL36 | ribosomal protein L36 | -0.0326894 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0326881 |
| PLAC8 | placenta-specific 8 | -0.0325372 |
| CUX1 | cut-like homeobox 1 | -0.0323315 |
