| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | 0.186005 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.126735 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.126461 |
| DST | dystonin | 0.123227 |
| HLA-B | major histocompatibility complex, class I, B | 0.119874 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.107248 |
| VIM | vimentin | 0.0964709 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0913286 |
| MT2A | metallothionein 2A | 0.082425 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0740068 |
| SP100 | SP100 nuclear antigen | 0.0739711 |
| PRELID2 | PRELI domain containing 2 | 0.0718396 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0714031 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.070867 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0682703 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0676182 |
| UBC | ubiquitin C | 0.0658069 |
| CADM2 | cell adhesion molecule 2 | 0.0639294 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.062701 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0606373 |
| ENO1 | enolase 1, (alpha) | 0.0590122 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0557539 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0554205 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0553775 |
| CD44 | CD44 molecule (Indian blood group) | 0.0527565 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0523443 |
| B2M | beta-2-microglobulin | 0.0518774 |
| RPS12 | ribosomal protein S12 | 0.0514455 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0504578 |
| CAPRIN2 | caprin family member 2 | 0.050076 |
| RNF213 | ring finger protein 213 | 0.0499778 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0498237 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0489417 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0481821 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0480291 |
| RAD51B | RAD51 paralog B | 0.0479253 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0471451 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0467787 |
| PLSCR1 | phospholipid scramblase 1 | 0.0466488 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0465555 |
| F2R | coagulation factor II (thrombin) receptor | 0.0461497 |
| VCL | vinculin | 0.0451134 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.042178 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0410288 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0404827 |
| PLK2 | polo-like kinase 2 | 0.0396751 |
| MT1E | metallothionein 1E | 0.0391196 |
| SVIL | supervillin | 0.0389951 |
| VMP1 | vacuole membrane protein 1 | 0.0385559 |
| HDAC9 | histone deacetylase 9 | 0.0377217 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0369751 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0367858 |
| H1-0 | H1.0 linker histone | 0.0364037 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0363524 |
| RIGI | RNA sensor RIG-I | 0.0363158 |
| HLA-A | major histocompatibility complex, class I, A | 0.0355028 |
| SYAP1 | synapse associated protein 1 | 0.035472 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0350443 |
| CEP128 | centrosomal protein 128kDa | 0.0350404 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.034691 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0339535 |
| ASPH | aspartate beta-hydroxylase | 0.033801 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0336034 |
| FHIT | fragile histidine triad | 0.0329617 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0327814 |
| PRKCE | protein kinase C, epsilon | 0.0327809 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0327083 |
| TPRG1 | tumor protein p63 regulated 1 | 0.0318567 |
| RTTN | rotatin | 0.0313407 |
| SMYD3 | SET and MYND domain containing 3 | 0.0311836 |
| HLA-E | major histocompatibility complex, class I, E | 0.0310959 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0310834 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0307222 |
| PDE10A | phosphodiesterase 10A | 0.0306584 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0305328 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0301501 |
| TRIM56 | tripartite motif containing 56 | 0.029823 |
| PMP22 | peripheral myelin protein 22 | 0.0289427 |
| SDC4 | syndecan 4 | 0.028589 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0284753 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0273802 |
| EREG | epiregulin | 0.027213 |
| RUNX1 | runt-related transcription factor 1 | 0.0269663 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0268994 |
| SQSTM1 | sequestosome 1 | 0.0267812 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0266706 |
| SAMHD1 | SAM domain and HD domain 1 | 0.0264175 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0263521 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0263052 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0262127 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0257495 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0256123 |
| ADAR | adenosine deaminase, RNA-specific | 0.0255065 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0254154 |
| DPH6 | diphthamine biosynthesis 6 | 0.025332 |
| AREG | amphiregulin | 0.0249842 |
| PCDH1 | protocadherin 1 | 0.024899 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0244796 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0243571 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0240689 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.212761 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.178805 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.112632 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.109034 |
| RAI1 | retinoic acid induced 1 | -0.0862435 |
| CANX | calnexin | -0.0853569 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0826131 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0693032 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0690062 |
| TXNRD1 | thioredoxin reductase 1 | -0.0588309 |
| HDLBP | high density lipoprotein binding protein | -0.0549716 |
| AHNAK | AHNAK nucleoprotein | -0.0540432 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0538882 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.051526 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0509496 |
| HMGA1 | high mobility group AT-hook 1 | -0.0508593 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.050581 |
| CENPF | centromere protein F, 350/400kDa | -0.0476084 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0449224 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0435835 |
| USP34 | ubiquitin specific peptidase 34 | -0.042679 |
| APP | amyloid beta (A4) precursor protein | -0.0422911 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0412873 |
| LDHA | lactate dehydrogenase A | -0.0390445 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0390396 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0383407 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0372412 |
| LOXL2 | lysyl oxidase-like 2 | -0.0371087 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0368588 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0362141 |
| MYOF | myoferlin | -0.0353644 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0353628 |
| MAP4 | microtubule-associated protein 4 | -0.034592 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0342451 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0340127 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0338593 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0336202 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0332063 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0332003 |
| YEATS2 | YEATS domain containing 2 | -0.0325794 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0323567 |
| NAV2 | neuron navigator 2 | -0.0321154 |
| FNDC3B | fibronectin type III domain containing 3B | -0.032093 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0314665 |
| SBF2 | SET binding factor 2 | -0.0314557 |
| ANXA1 | annexin A1 | -0.0304298 |
| UPP1 | uridine phosphorylase 1 | -0.0296323 |
| TMEM41B | transmembrane protein 41B | -0.0295684 |
| RPL35A | ribosomal protein L35a | -0.029313 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0287217 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0286878 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0286405 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0283983 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0276157 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0276133 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0274623 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0274313 |
| GOLGA4 | golgin A4 | -0.0269029 |
| TOP1 | topoisomerase (DNA) I | -0.0268497 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0263076 |
| EHBP1 | EH domain binding protein 1 | -0.0259259 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0257379 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0256792 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0256333 |
| ZFR | zinc finger RNA binding protein | -0.0253388 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0251455 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0250251 |
| MORF4L2 | mortality factor 4 like 2 | -0.0250236 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0249042 |
| TAOK1 | TAO kinase 1 | -0.024656 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0245191 |
| POTEF | POTE ankyrin domain family, member F | -0.0244416 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0243898 |
| WASF2 | WAS protein family, member 2 | -0.0242344 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0240775 |
| PODXL | podocalyxin-like | -0.0238196 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0237968 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0237717 |
| NBAS | neuroblastoma amplified sequence | -0.0237057 |
| TMEM123 | transmembrane protein 123 | -0.0236421 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0235286 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0234993 |
| NUP58 | nucleoporin 58 | -0.0233529 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0233167 |
| STK17A | serine/threonine kinase 17a | -0.0232788 |
| COG5 | component of oligomeric golgi complex 5 | -0.023203 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0231346 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0230735 |
| CLTC | clathrin, heavy chain (Hc) | -0.0229228 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0228973 |
| LRRC49 | leucine rich repeat containing 49 | -0.0228481 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0227598 |
| SNX14 | sorting nexin 14 | -0.022732 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0226915 |
| SRP54 | signal recognition particle 54kDa | -0.0226869 |
| DENND1A | DENN/MADD domain containing 1A | -0.0225847 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0224329 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0222009 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0220595 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0219961 |
