| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.334805 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.101568 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0888531 |
| STC1 | stanniocalcin 1 | 0.086494 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0835194 |
| TXNRD1 | thioredoxin reductase 1 | 0.0803947 |
| GRAMD1B | GRAM domain containing 1B | 0.0783945 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0778027 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0775361 |
| ENO1 | enolase 1, (alpha) | 0.0753627 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0748136 |
| SLTM | SAFB-like, transcription modulator | 0.0723145 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0684777 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0678573 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0634518 |
| SP100 | SP100 nuclear antigen | 0.0606511 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0537611 |
| UBC | ubiquitin C | 0.0535075 |
| CPE | carboxypeptidase E | 0.0522511 |
| CES1 | carboxylesterase 1 | 0.0470746 |
| MKI67 | marker of proliferation Ki-67 | 0.0462784 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.045832 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0449509 |
| LAMA4 | laminin, alpha 4 | 0.0444157 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0433437 |
| BPTF | bromodomain PHD finger transcription factor | 0.0421815 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0419178 |
| AHNAK | AHNAK nucleoprotein | 0.0399409 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0391334 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0387489 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0385023 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0365979 |
| ARRDC3 | arrestin domain containing 3 | 0.0358726 |
| RNF213 | ring finger protein 213 | 0.0355414 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0352316 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0346148 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0339453 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0328689 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.032226 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0317112 |
| MX1 | MX dynamin-like GTPase 1 | 0.0312414 |
| GPHN | gephyrin | 0.0311649 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0310783 |
| EXOC6B | exocyst complex component 6B | 0.0310596 |
| ADAR | adenosine deaminase, RNA-specific | 0.0310081 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0308781 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0303917 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0300679 |
| DSPP | dentin sialophosphoprotein | 0.0295724 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0294049 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0285877 |
| AREG | amphiregulin | 0.0283437 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0278737 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0278564 |
| RPS25 | ribosomal protein S25 | 0.0277102 |
| LDHA | lactate dehydrogenase A | 0.0276994 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.027242 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.027172 |
| RPS3 | ribosomal protein S3 | 0.0270691 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0270567 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0266403 |
| MCL1 | myeloid cell leukemia 1 | 0.025997 |
| HLA-B | major histocompatibility complex, class I, B | 0.0259468 |
| CDCP1 | CUB domain containing protein 1 | 0.0256481 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0253888 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.025259 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0251745 |
| FHL2 | four and a half LIM domains 2 | 0.0251681 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0251408 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0250929 |
| CEP350 | centrosomal protein 350kDa | 0.0248343 |
| KIAA1217 | KIAA1217 | 0.0248219 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0248021 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0244905 |
| MAP7 | microtubule-associated protein 7 | 0.0239529 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0237333 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0236885 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0233183 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0232613 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0231094 |
| FAT1 | FAT atypical cadherin 1 | 0.0229825 |
| FAM107B | family with sequence similarity 107, member B | 0.0228315 |
| RAD51B | RAD51 paralog B | 0.0224496 |
| MYO9A | myosin IXA | 0.0221781 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0221007 |
| RPS8 | ribosomal protein S8 | 0.0220197 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0219988 |
| PYGL | phosphorylase, glycogen, liver | 0.0218818 |
| RPS27A | ribosomal protein S27a | 0.021873 |
| ATG12 | autophagy related 12 | 0.0217368 |
| CPNE4 | copine IV | 0.0211073 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0210603 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0210498 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0210457 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0210321 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0208086 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0206712 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0203753 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0202475 |
| ITSN2 | intersectin 2 | 0.0200006 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | -0.104482 |
| TMSB10 | thymosin beta 10 | -0.0967852 |
| ASPH | aspartate beta-hydroxylase | -0.0879534 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0759741 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0758215 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0681974 |
| EGFR | epidermal growth factor receptor | -0.0664625 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0647981 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0622917 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0609527 |
| SCEL | sciellin | -0.0603666 |
| NDRG1 | N-myc downstream regulated 1 | -0.0570034 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0532536 |
| LAMC2 | laminin, gamma 2 | -0.0522227 |
| FNIP1 | folliculin interacting protein 1 | -0.0511702 |
| TMEM165 | transmembrane protein 165 | -0.0499441 |
| RUNX1 | runt-related transcription factor 1 | -0.0451118 |
| HDLBP | high density lipoprotein binding protein | -0.0444658 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0440021 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0432585 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0415816 |
| POTEF | POTE ankyrin domain family, member F | -0.0415433 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.04101 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0394969 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0359042 |
| KRT7 | keratin 7, type II | -0.0354699 |
| RAB1A | RAB1A, member RAS oncogene family | -0.035433 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0351633 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0348221 |
| RASA2 | RAS p21 protein activator 2 | -0.0340039 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0339844 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0332489 |
| SEPTIN2 | septin 2 | -0.0330378 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0323955 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0318674 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0313467 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0310955 |
| TXNDC11 | thioredoxin domain containing 11 | -0.0306412 |
| NABP1 | nucleic acid binding protein 1 | -0.0301618 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0300669 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0299738 |
| NBAS | neuroblastoma amplified sequence | -0.0297812 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0297526 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0294348 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0293673 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0289843 |
| LAMB3 | laminin, beta 3 | -0.0287861 |
| USP34 | ubiquitin specific peptidase 34 | -0.0277256 |
| SDC1 | syndecan 1 | -0.027668 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0276097 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0272041 |
| AFDN | afadin, adherens junction formation factor | -0.0269753 |
| FRYL | FRY-like | -0.0268933 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0268719 |
| HYOU1 | hypoxia up-regulated 1 | -0.0266066 |
| RCOR1 | REST corepressor 1 | -0.0266035 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0263281 |
| RNF145 | ring finger protein 145 | -0.0262826 |
| PRKCA | protein kinase C, alpha | -0.0262398 |
| CD163L1 | CD163 molecule-like 1 | -0.0261264 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0260949 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0260448 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0259908 |
| SRP54 | signal recognition particle 54kDa | -0.0254313 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0254056 |
| TJP1 | tight junction protein 1 | -0.0251602 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0251332 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0249325 |
| CLTC | clathrin, heavy chain (Hc) | -0.0246563 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0244572 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0243687 |
| GPC6 | glypican 6 | -0.0241777 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0239379 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0235992 |
| RIN2 | Ras and Rab interactor 2 | -0.0234782 |
| SUCO | SUN domain containing ossification factor | -0.0230591 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0229897 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0223659 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0222582 |
| SEPTIN10 | septin 10 | -0.022252 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0222151 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0216367 |
| SMAD4 | SMAD family member 4 | -0.0216178 |
| DHFR | dihydrofolate reductase | -0.0214668 |
| TPD52 | tumor protein D52 | -0.0214053 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0213718 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0213291 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0210853 |
| UBAC2 | UBA domain containing 2 | -0.0210346 |
| MED13L | mediator complex subunit 13-like | -0.0209851 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.02085 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0208051 |
| CTBP2 | C-terminal binding protein 2 | -0.0206045 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0202653 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0199589 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0199461 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0197912 |
| UVSSA | UV-stimulated scaffold protein A | -0.0197121 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0196926 |
| LAMA5 | laminin, alpha 5 | -0.019614 |
