| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0745642 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0519501 |
| SMAD3 | SMAD family member 3 | 0.0354544 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.034414 |
| SYT1 | synaptotagmin I | 0.0327233 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0322971 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0320851 |
| NRP1 | neuropilin 1 | 0.029658 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0267759 |
| GLCCI1 | glucocorticoid induced 1 | 0.0255183 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.025494 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0252927 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0247885 |
| DST | dystonin | 0.0242403 |
| STK38L | serine/threonine kinase 38 like | 0.0240471 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0233244 |
| NTN4 | netrin 4 | 0.022983 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0218513 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0218072 |
| RAD51B | RAD51 paralog B | 0.0206017 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0205213 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0204866 |
| CD44 | CD44 molecule (Indian blood group) | 0.020407 |
| EZR | ezrin | 0.0194335 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0192327 |
| IL1R1 | interleukin 1 receptor, type I | 0.0181324 |
| PLEC | plectin | 0.0169431 |
| KYNU | kynureninase | 0.0168407 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0164544 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0162826 |
| SVIL | supervillin | 0.0160954 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0154606 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0150835 |
| WLS | wntless Wnt ligand secretion mediator | 0.0150809 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0148917 |
| LAMA4 | laminin, alpha 4 | 0.0146605 |
| MX1 | MX dynamin-like GTPase 1 | 0.0146549 |
| TGM2 | transglutaminase 2 | 0.0139924 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0138494 |
| SLTM | SAFB-like, transcription modulator | 0.0137726 |
| RUNX2 | runt-related transcription factor 2 | 0.0134437 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0133112 |
| LAMB1 | laminin, beta 1 | 0.0132683 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0132389 |
| FHIT | fragile histidine triad | 0.0131706 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0131426 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0130365 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0130255 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0129812 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0128438 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0127721 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0127422 |
| KSR1 | kinase suppressor of ras 1 | 0.0125528 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0123305 |
| ZNF385D | zinc finger protein 385D | 0.0122311 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0121868 |
| SUMF1 | sulfatase modifying factor 1 | 0.0120479 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0118278 |
| FLNA | filamin A, alpha | 0.011821 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0117677 |
| MAP1B | microtubule-associated protein 1B | 0.011749 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0117198 |
| ADD3 | adducin 3 (gamma) | 0.0116169 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0115048 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0114544 |
| ECE1 | endothelin converting enzyme 1 | 0.0114539 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0113863 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0113012 |
| TXNRD1 | thioredoxin reductase 1 | 0.0109019 |
| SYNJ2 | synaptojanin 2 | 0.010883 |
| IL6ST | interleukin 6 signal transducer | 0.0107434 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0106086 |
| CDCP1 | CUB domain containing protein 1 | 0.0104609 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0104539 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.010419 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0103074 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0102169 |
| VEGFC | vascular endothelial growth factor C | 0.0102166 |
| ZNF804A | zinc finger protein 804A | 0.0100766 |
| EXOC6B | exocyst complex component 6B | 0.0100304 |
| MSN | moesin | 0.0100249 |
| STX1A | syntaxin 1A (brain) | 0.00998989 |
| IGSF1 | immunoglobulin superfamily, member 1 | 0.00992055 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00991946 |
| STPG2 | sperm-tail PG-rich repeat containing 2 | 0.00989114 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.00980299 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00974208 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.00973431 |
| CEP250 | centrosomal protein 250kDa | 0.00969859 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.00961519 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.009593 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.00957754 |
| POU6F2 | POU class 6 homeobox 2 | 0.00953438 |
| CAPRIN2 | caprin family member 2 | 0.00950506 |
| MYO10 | myosin X | 0.0093852 |
| PLXNA1 | plexin A1 | 0.00924714 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.00920887 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.00919982 |
| WWOX | WW domain containing oxidoreductase | 0.00909374 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.00907036 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.252969 |
| TMSB10 | thymosin beta 10 | -0.239994 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180599 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.14682 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.128043 |
| FTL | ferritin, light polypeptide | -0.104042 |
| PTMA | prothymosin, alpha | -0.103369 |
| STC1 | stanniocalcin 1 | -0.101498 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0893503 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0890711 |
| RPLP1 | ribosomal protein, large, P1 | -0.087575 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0849803 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0844917 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0836734 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0728487 |
| GOLGA4 | golgin A4 | -0.0725244 |
| MT2A | metallothionein 2A | -0.0723911 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0705864 |
| RPL35A | ribosomal protein L35a | -0.069013 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0688543 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0675927 |
| S100A6 | S100 calcium binding protein A6 | -0.0658653 |
| B2M | beta-2-microglobulin | -0.0646899 |
| USP34 | ubiquitin specific peptidase 34 | -0.064608 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0643592 |
| RPS19 | ribosomal protein S19 | -0.06337 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0608878 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0594488 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.057182 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0564493 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.056308 |
| CDH13 | cadherin 13 | -0.0558624 |
| NDRG1 | N-myc downstream regulated 1 | -0.0542927 |
| RPS8 | ribosomal protein S8 | -0.0531427 |
| RPL34 | ribosomal protein L34 | -0.0526295 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0525222 |
| ENO1 | enolase 1, (alpha) | -0.0516133 |
| RPS21 | ribosomal protein S21 | -0.0514371 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0511167 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0500346 |
| LDHA | lactate dehydrogenase A | -0.0498195 |
| RPS6 | ribosomal protein S6 | -0.0492111 |
| RPS24 | ribosomal protein S24 | -0.0489995 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0476188 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.04747 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0472872 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0468495 |
| RPL31 | ribosomal protein L31 | -0.046568 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0465558 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0456148 |
| RPL37A | ribosomal protein L37a | -0.0455519 |
| MTSS1 | metastasis suppressor 1 | -0.0443694 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0442152 |
| HMGA1 | high mobility group AT-hook 1 | -0.0440076 |
| MEF2A | myocyte enhancer factor 2A | -0.0439729 |
| FAM20C | family with sequence similarity 20, member C | -0.0438554 |
| IER3 | immediate early response 3 | -0.0432099 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0428071 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0427329 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0425701 |
| RPL23 | ribosomal protein L23 | -0.0421036 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.04192 |
| RPLP2 | ribosomal protein, large, P2 | -0.0410476 |
| RPS13 | ribosomal protein S13 | -0.0406986 |
| RPS29 | ribosomal protein S29 | -0.0404708 |
| RPLP0 | ribosomal protein, large, P0 | -0.0402678 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0398512 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0397735 |
| TMEM165 | transmembrane protein 165 | -0.0393408 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0393264 |
| GNAS | GNAS complex locus | -0.0390005 |
| NUMB | numb homolog (Drosophila) | -0.0389456 |
| RPL32 | ribosomal protein L32 | -0.0389036 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.038852 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.038793 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0386547 |
| RIOK3 | RIO kinase 3 | -0.0386185 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.038585 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0371475 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0369309 |
| PGK1 | phosphoglycerate kinase 1 | -0.0367606 |
| TMEM263 | transmembrane protein 263 | -0.0367193 |
| HLA-B | major histocompatibility complex, class I, B | -0.0366125 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.03634 |
| PCBP2 | poly(rC) binding protein 2 | -0.0362239 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0360436 |
| RBM39 | RNA binding motif protein 39 | -0.0360307 |
| CALU | calumenin | -0.0359188 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0355688 |
| RPS25 | ribosomal protein S25 | -0.0352256 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0345401 |
| S100A10 | S100 calcium binding protein A10 | -0.0343208 |
| RPL11 | ribosomal protein L11 | -0.0342051 |
| RPS11 | ribosomal protein S11 | -0.0340002 |
| HM13 | histocompatibility (minor) 13 | -0.0338677 |
| HDLBP | high density lipoprotein binding protein | -0.0338391 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0338027 |
| POTEF | POTE ankyrin domain family, member F | -0.0337436 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0330811 |
| RPL37 | ribosomal protein L37 | -0.0327949 |
