| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.300759 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.179739 |
| LMO7 | LIM domain 7 | 0.0919743 |
| DSPP | dentin sialophosphoprotein | 0.0777785 |
| LAMC2 | laminin, gamma 2 | 0.0750259 |
| FBXO32 | F-box protein 32 | 0.0723694 |
| MAP1B | microtubule-associated protein 1B | 0.0698565 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0645181 |
| CTSB | cathepsin B | 0.0643047 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0635837 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0580286 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0577812 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0570766 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0544753 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0524379 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0521905 |
| UBC | ubiquitin C | 0.0504969 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.049746 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0497161 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.048963 |
| EXT1 | exostosin glycosyltransferase 1 | 0.048459 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0477662 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0459584 |
| FTL | ferritin, light polypeptide | 0.044968 |
| TXNIP | thioredoxin interacting protein | 0.0445062 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0437652 |
| RNF213 | ring finger protein 213 | 0.0434884 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0434785 |
| AHNAK | AHNAK nucleoprotein | 0.043191 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0425836 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0411717 |
| MX1 | MX dynamin-like GTPase 1 | 0.0409908 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0397416 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0391996 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0381 |
| RAI14 | retinoic acid induced 14 | 0.0380675 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0378514 |
| MX2 | MX dynamin-like GTPase 2 | 0.0377863 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0367257 |
| PLEC | plectin | 0.0366372 |
| ERBIN | erbb2 interacting protein | 0.0364875 |
| H1-0 | H1.0 linker histone | 0.0360476 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0357813 |
| GOLGB1 | golgin B1 | 0.0347604 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0347243 |
| SP100 | SP100 nuclear antigen | 0.0339067 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.033527 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0334028 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0329598 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0324978 |
| ETV6 | ets variant 6 | 0.0320179 |
| BPTF | bromodomain PHD finger transcription factor | 0.0313958 |
| CSTB | cystatin B (stefin B) | 0.0308112 |
| MYO6 | myosin VI | 0.0304456 |
| TPM4 | tropomyosin 4 | 0.0302372 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0300455 |
| SVIL | supervillin | 0.0297601 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0296831 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0294187 |
| CD44 | CD44 molecule (Indian blood group) | 0.0293709 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0292174 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0285805 |
| CTSS | cathepsin S | 0.028446 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0283277 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0276821 |
| RASAL2 | RAS protein activator like 2 | 0.0275916 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0274454 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0270119 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0266708 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0266331 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.026614 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0263153 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0260611 |
| EGFR | epidermal growth factor receptor | 0.0258266 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0254984 |
| TPM3 | tropomyosin 3 | 0.0252776 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0250746 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.0249275 |
| DST | dystonin | 0.0246763 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.024404 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0243554 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0243051 |
| RAB27B | RAB27B, member RAS oncogene family | 0.024238 |
| MSN | moesin | 0.024159 |
| JUP | junction plakoglobin | 0.0240863 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0240741 |
| MKI67 | marker of proliferation Ki-67 | 0.0240284 |
| MYO5B | myosin VB | 0.0240107 |
| FNBP4 | formin binding protein 4 | 0.0238906 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0238733 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0235454 |
| RBM47 | RNA binding motif protein 47 | 0.0234482 |
| OSMR | oncostatin M receptor | 0.023254 |
| BCL2L1 | BCL2-like 1 | 0.0229858 |
| ENO1 | enolase 1, (alpha) | 0.0229847 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0229596 |
| ATXN1 | ataxin 1 | 0.022788 |
| EPCAM | epithelial cell adhesion molecule | 0.0222051 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0220352 |
| TMSB4X | thymosin beta 4, X-linked | 0.0219614 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.227433 |
| FN1 | fibronectin 1 | -0.21142 |
| NDRG1 | N-myc downstream regulated 1 | -0.168119 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.167298 |
| FNDC3B | fibronectin type III domain containing 3B | -0.148433 |
| TSC22D2 | TSC22 domain family, member 2 | -0.112429 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.100976 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.100956 |
| HMGA1 | high mobility group AT-hook 1 | -0.0948747 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0756206 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0716132 |
| RPL35A | ribosomal protein L35a | -0.0702879 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0667129 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0660946 |
| ASPH | aspartate beta-hydroxylase | -0.0616308 |
| POTEF | POTE ankyrin domain family, member F | -0.0602761 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0589549 |
| TFG | TRK-fused gene | -0.0586865 |
| RNF145 | ring finger protein 145 | -0.0583258 |
| FAM13A | family with sequence similarity 13, member A | -0.055471 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0549514 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0527571 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0521062 |
| USP3 | ubiquitin specific peptidase 3 | -0.0502035 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0497821 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0491456 |
| CDC73 | cell division cycle 73 | -0.048395 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0476517 |
| FAM3C | family with sequence similarity 3, member C | -0.0471113 |
| TMSB10 | thymosin beta 10 | -0.0470979 |
| RBM39 | RNA binding motif protein 39 | -0.0462305 |
| RPL34 | ribosomal protein L34 | -0.0452823 |
| SPAG9 | sperm associated antigen 9 | -0.0449614 |
| RPLP1 | ribosomal protein, large, P1 | -0.0448311 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.044639 |
| MATR3 | matrin 3 | -0.0441622 |
| ZNF292 | zinc finger protein 292 | -0.0430138 |
| RACK1 | receptor for activated C kinase 1 | -0.0430065 |
| GOLGA4 | golgin A4 | -0.0428351 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0427254 |
| RPL9 | ribosomal protein L9 | -0.0415666 |
| GNAS | GNAS complex locus | -0.041021 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0398074 |
| RPL30 | ribosomal protein L30 | -0.0396346 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0394208 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0392701 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0392073 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0390859 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0388664 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0380545 |
| RPS23 | ribosomal protein S23 | -0.0379079 |
| SDC4 | syndecan 4 | -0.037813 |
| RLF | rearranged L-myc fusion | -0.0375233 |
| S100A6 | S100 calcium binding protein A6 | -0.036163 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0358519 |
| TOP1 | topoisomerase (DNA) I | -0.0357905 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0356293 |
| ANXA5 | annexin A5 | -0.0355015 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0350175 |
| RYBP | RING1 and YY1 binding protein | -0.0348816 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0341622 |
| QKI | QKI, KH domain containing, RNA binding | -0.0338685 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0338565 |
| RPL11 | ribosomal protein L11 | -0.0338207 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0336927 |
| CCNL1 | cyclin L1 | -0.0336758 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0336468 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.033547 |
| CDK17 | cyclin-dependent kinase 17 | -0.033474 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.033294 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0332722 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0331192 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0330518 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0329943 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0329262 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0326972 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0322904 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0321712 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.032112 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0320709 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0316831 |
| AZIN1 | antizyme inhibitor 1 | -0.0315517 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.031535 |
| LDHA | lactate dehydrogenase A | -0.0314632 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0314592 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0312757 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0308828 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0305935 |
| RPS24 | ribosomal protein S24 | -0.0304812 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.030404 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0302331 |
| HMGB2 | high mobility group box 2 | -0.0300489 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.029989 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0299106 |
| NUP58 | nucleoporin 58 | -0.0297456 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0297188 |
| CD109 | CD109 molecule | -0.029569 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0294883 |
| PLAU | plasminogen activator, urokinase | -0.0294611 |
| RPS8 | ribosomal protein S8 | -0.0294055 |
