| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.176562 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.118123 |
| PEG10 | paternally expressed 10 | 0.0878436 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0618919 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0544146 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.052797 |
| THBS1 | thrombospondin 1 | 0.052733 |
| CADM2 | cell adhesion molecule 2 | 0.0517217 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0513181 |
| PCDH9 | protocadherin 9 | 0.0478405 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0445809 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0419833 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0419503 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0386292 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0372617 |
| MKI67 | marker of proliferation Ki-67 | 0.0371747 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0364766 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0355602 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0354801 |
| PLPP1 | phospholipid phosphatase 1 | 0.034462 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0340772 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 0.0330467 |
| CDH19 | cadherin 19, type 2 | 0.0326192 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0319222 |
| SYT1 | synaptotagmin I | 0.0318165 |
| KIAA1328 | KIAA1328 | 0.03102 |
| CANX | calnexin | 0.0295554 |
| METAP2 | methionyl aminopeptidase 2 | 0.0288238 |
| PCDH7 | protocadherin 7 | 0.0288098 |
| USP34 | ubiquitin specific peptidase 34 | 0.0285613 |
| GPC3 | glypican 3 | 0.0285547 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0284632 |
| RAD51B | RAD51 paralog B | 0.0283059 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0283054 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0283031 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0281239 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0277537 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0276249 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.026682 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0265021 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0263789 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0258478 |
| SHROOM3 | shroom family member 3 | 0.0256232 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0249559 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.024374 |
| PCDH18 | protocadherin 18 | 0.0243629 |
| IGF2 | insulin-like growth factor 2 | 0.024149 |
| EZR | ezrin | 0.0238535 |
| OTOGL | otogelin-like | 0.0236547 |
| DENND1A | DENN/MADD domain containing 1A | 0.023407 |
| CENPF | centromere protein F, 350/400kDa | 0.0231269 |
| LRRC4C | leucine rich repeat containing 4C | 0.0231173 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0230875 |
| HMGA2 | high mobility group AT-hook 2 | 0.0226413 |
| TENM2 | teneurin transmembrane protein 2 | 0.0225825 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0224836 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0222685 |
| MYO9A | myosin IXA | 0.021716 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0216917 |
| FAT1 | FAT atypical cadherin 1 | 0.0215633 |
| TMSB4X | thymosin beta 4, X-linked | 0.0212064 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0211964 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0211127 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0210591 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0210272 |
| UTRN | utrophin | 0.020843 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0208363 |
| STK39 | serine threonine kinase 39 | 0.020414 |
| FOXP2 | forkhead box P2 | 0.0204061 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0203721 |
| LYST | lysosomal trafficking regulator | 0.020278 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0201721 |
| INTS6 | integrator complex subunit 6 | 0.020101 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.020037 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0200041 |
| CEP295 | centrosomal protein 295kDa | 0.0197519 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0196244 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0194997 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0194456 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0194419 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0193953 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.01933 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0193227 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0192629 |
| EXOC4 | exocyst complex component 4 | 0.0191921 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.019036 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0188867 |
| COMMD10 | COMM domain containing 10 | 0.0186957 |
| DSPP | dentin sialophosphoprotein | 0.0184212 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0184103 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0182436 |
| VCP | valosin containing protein | 0.0181809 |
| MYO6 | myosin VI | 0.0181575 |
| MPG | N-methylpurine-DNA glycosylase | 0.0179515 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0179397 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0179187 |
| FMNL2 | formin-like 2 | 0.0177409 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0174262 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.017309 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0172666 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.187348 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0994647 |
| RPS16 | ribosomal protein S16 | -0.0968309 |
| RPL35A | ribosomal protein L35a | -0.0930031 |
| RPS6 | ribosomal protein S6 | -0.092976 |
| PTMA | prothymosin, alpha | -0.0901334 |
| VIM | vimentin | -0.0745927 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0723452 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0718747 |
| RPLP1 | ribosomal protein, large, P1 | -0.0716756 |
| RPS8 | ribosomal protein S8 | -0.0715508 |
| PGK1 | phosphoglycerate kinase 1 | -0.0706546 |
| GNAS | GNAS complex locus | -0.0646732 |
| RPL11 | ribosomal protein L11 | -0.0645278 |
| ACTG1 | actin gamma 1 | -0.0634594 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0585438 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0573929 |
| RPL5 | ribosomal protein L5 | -0.0567896 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0557677 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0556759 |
| POTEF | POTE ankyrin domain family, member F | -0.054987 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0549324 |
| SNX6 | sorting nexin 6 | -0.0532686 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0530128 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0516702 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.051352 |
| RPS19 | ribosomal protein S19 | -0.0512117 |
| SRP54 | signal recognition particle 54kDa | -0.0507938 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0504138 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0501285 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0495478 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.049208 |
| ANKRD33B | ankyrin repeat domain 33B | -0.048982 |
| PFN1 | profilin 1 | -0.0475357 |
| PRTG | protogenin | -0.0474038 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0466454 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0464527 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.046353 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0463361 |
| RTN4 | reticulon 4 | -0.0445798 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0445297 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0442098 |
| MTF2 | metal response element binding transcription factor 2 | -0.0439803 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0437433 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0431151 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0428561 |
| RPL23 | ribosomal protein L23 | -0.0422183 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0416416 |
| PDGFC | platelet derived growth factor C | -0.0413841 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0410037 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0408482 |
| MYL12B | myosin, light chain 12B, regulatory | -0.040823 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0407079 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0404735 |
| RBM39 | RNA binding motif protein 39 | -0.0398739 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0397209 |
| RPL30 | ribosomal protein L30 | -0.0396486 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0395957 |
| THOC2 | THO complex 2 | -0.0392675 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0391803 |
| B2M | beta-2-microglobulin | -0.0383352 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0383135 |
| ATXN2 | ataxin 2 | -0.0378459 |
| RPS21 | ribosomal protein S21 | -0.0377045 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0376336 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0375094 |
| S100A9 | S100 calcium binding protein A9 | -0.0374993 |
| COL5A2 | collagen, type V, alpha 2 | -0.0374906 |
| ZNF292 | zinc finger protein 292 | -0.0371385 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0370959 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0369579 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0368751 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0368024 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0365724 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0364531 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0359722 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0356315 |
| RPLP0 | ribosomal protein, large, P0 | -0.0354621 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0352805 |
| RBM25 | RNA binding motif protein 25 | -0.034955 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0346984 |
| TRERF1 | transcriptional regulating factor 1 | -0.0345784 |
| RPS25 | ribosomal protein S25 | -0.0341938 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0341788 |
| RAI1 | retinoic acid induced 1 | -0.0340557 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0339768 |
| RHEB | Ras homolog enriched in brain | -0.0338982 |
| FTL | ferritin, light polypeptide | -0.0337429 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0333408 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0329637 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0329577 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0329281 |
| USP3 | ubiquitin specific peptidase 3 | -0.0329066 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0327957 |
| ACTN4 | actinin, alpha 4 | -0.0327482 |
| LDHA | lactate dehydrogenase A | -0.0327192 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.032525 |
| WASF2 | WAS protein family, member 2 | -0.0322135 |
| SRPK2 | SRSF protein kinase 2 | -0.03206 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0319985 |
