| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.101406 |
| LAMA4 | laminin, alpha 4 | 0.0930486 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0828307 |
| MUC16 | mucin 16, cell surface associated | 0.079408 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0703227 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0702228 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0681078 |
| C3 | complement component 3 | 0.06186 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0581274 |
| MKI67 | marker of proliferation Ki-67 | 0.0565093 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.052638 |
| MX1 | MX dynamin-like GTPase 1 | 0.0516726 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0485096 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0480574 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0477674 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0473848 |
| DST | dystonin | 0.0465132 |
| DSPP | dentin sialophosphoprotein | 0.0458722 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.045304 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0451874 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0443167 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.042959 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0422571 |
| CCNL1 | cyclin L1 | 0.0414999 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0413079 |
| TXNRD1 | thioredoxin reductase 1 | 0.0409334 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0407481 |
| ENO1 | enolase 1, (alpha) | 0.0400945 |
| RASAL2 | RAS protein activator like 2 | 0.0396919 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0389937 |
| THBS1 | thrombospondin 1 | 0.0388401 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0386572 |
| VMP1 | vacuole membrane protein 1 | 0.0375688 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0369497 |
| FHIT | fragile histidine triad | 0.0350354 |
| ITGA6 | integrin, alpha 6 | 0.0349966 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0349265 |
| AREG | amphiregulin | 0.0347586 |
| TXNIP | thioredoxin interacting protein | 0.0344352 |
| TGM2 | transglutaminase 2 | 0.0339723 |
| FLNA | filamin A, alpha | 0.0335377 |
| CD44 | CD44 molecule (Indian blood group) | 0.0334218 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0327183 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0321672 |
| EHF | ets homologous factor | 0.0313031 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0310929 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0305773 |
| CALR | calreticulin | 0.0292244 |
| IFI44L | interferon-induced protein 44-like | 0.0291186 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0289457 |
| PCDH1 | protocadherin 1 | 0.0286489 |
| LAMB1 | laminin, beta 1 | 0.0285629 |
| ACTN1 | actinin, alpha 1 | 0.0284626 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0282905 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0282418 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.027732 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0272021 |
| TPM3 | tropomyosin 3 | 0.0263039 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0260116 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0257105 |
| IL6ST | interleukin 6 signal transducer | 0.025608 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0252894 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0251635 |
| AHR | aryl hydrocarbon receptor | 0.025028 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0249719 |
| EHBP1 | EH domain binding protein 1 | 0.0246065 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0244953 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0244806 |
| GPHN | gephyrin | 0.0244661 |
| SET | SET nuclear proto-oncogene | 0.0242121 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0236782 |
| CENPF | centromere protein F, 350/400kDa | 0.0233799 |
| EFNA5 | ephrin-A5 | 0.0230304 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0227792 |
| MX2 | MX dynamin-like GTPase 2 | 0.0223975 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0221209 |
| RNF213 | ring finger protein 213 | 0.0220272 |
| KRT18 | keratin 18, type I | 0.0216916 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0216789 |
| PRELID2 | PRELI domain containing 2 | 0.0215575 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0214441 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0213905 |
| RPL21 | ribosomal protein L21 | 0.0212857 |
| SLTM | SAFB-like, transcription modulator | 0.0212723 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0210835 |
| STK17B | serine/threonine kinase 17b | 0.0210671 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0210165 |
| BPTF | bromodomain PHD finger transcription factor | 0.0205405 |
| PNN | pinin, desmosome associated protein | 0.0204888 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0203552 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.020245 |
| SFTPA2 | surfactant protein A2 | 0.0198195 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0197667 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0194738 |
| SGMS2 | sphingomyelin synthase 2 | 0.019307 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0191182 |
| PLK2 | polo-like kinase 2 | 0.0190963 |
| ANXA1 | annexin A1 | 0.0190838 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.019076 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0188885 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | -0.176232 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.169338 |
| PTMA | prothymosin, alpha | -0.143468 |
| RPL35A | ribosomal protein L35a | -0.131659 |
| HMGA1 | high mobility group AT-hook 1 | -0.124095 |
| ACTG1 | actin gamma 1 | -0.115042 |
| TMSB10 | thymosin beta 10 | -0.107524 |
| MYO6 | myosin VI | -0.102326 |
| TMSB4X | thymosin beta 4, X-linked | -0.100866 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0976753 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0928972 |
| HLA-B | major histocompatibility complex, class I, B | -0.0865641 |
| RPLP1 | ribosomal protein, large, P1 | -0.081533 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0791803 |
| HLA-E | major histocompatibility complex, class I, E | -0.0756803 |
| RPL34 | ribosomal protein L34 | -0.070278 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0662212 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0659044 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0643376 |
| TPM4 | tropomyosin 4 | -0.0639208 |
| RPS6 | ribosomal protein S6 | -0.0625569 |
| KRT7 | keratin 7, type II | -0.0611791 |
| RPS8 | ribosomal protein S8 | -0.0606275 |
| RPS24 | ribosomal protein S24 | -0.0596999 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0594685 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0589304 |
| NDRG1 | N-myc downstream regulated 1 | -0.058625 |
| RIOK3 | RIO kinase 3 | -0.0567577 |
| GNAS | GNAS complex locus | -0.0566731 |
| RPS19 | ribosomal protein S19 | -0.0561801 |
| KRT17 | keratin 17, type I | -0.055541 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.054785 |
| ANXA2 | annexin A2 | -0.0538384 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0536716 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0531682 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0523543 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0516867 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0501064 |
| RPS29 | ribosomal protein S29 | -0.0498584 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.049539 |
| LDHA | lactate dehydrogenase A | -0.0489768 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0489435 |
| SYT14 | synaptotagmin XIV | -0.0484118 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.048334 |
| FOXO3 | forkhead box O3 | -0.0480672 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0470427 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.046776 |
| SQSTM1 | sequestosome 1 | -0.0453578 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0451183 |
| MEF2A | myocyte enhancer factor 2A | -0.0434327 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0431729 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0424495 |
| RPL31 | ribosomal protein L31 | -0.0422416 |
| LMO7 | LIM domain 7 | -0.0419792 |
| RPL23 | ribosomal protein L23 | -0.0413568 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0410492 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0407863 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0407607 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0406444 |
| DAPK1 | death-associated protein kinase 1 | -0.0406322 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0400183 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0398379 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.039583 |
| RPL37A | ribosomal protein L37a | -0.0395449 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0395084 |
| RPL37 | ribosomal protein L37 | -0.0392063 |
| RPL8 | ribosomal protein L8 | -0.0387735 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0385475 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0383036 |
| DSG2 | desmoglein 2 | -0.0379006 |
| HLA-C | major histocompatibility complex, class I, C | -0.0377383 |
| CD47 | CD47 molecule | -0.0369121 |
| AHNAK | AHNAK nucleoprotein | -0.0368878 |
| ASS1 | argininosuccinate synthase 1 | -0.0368709 |
| RPL12 | ribosomal protein L12 | -0.0367585 |
| LASP1 | LIM and SH3 protein 1 | -0.0366736 |
| RPL30 | ribosomal protein L30 | -0.0363628 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0358168 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.035711 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0349629 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0349389 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0345026 |
| ERBIN | erbb2 interacting protein | -0.0343424 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0340561 |
| RPL26 | ribosomal protein L26 | -0.0339518 |
| FN1 | fibronectin 1 | -0.0336727 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0336367 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0335901 |
| RPS21 | ribosomal protein S21 | -0.0335095 |
| RPS23 | ribosomal protein S23 | -0.0333269 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0329806 |
| CD2AP | CD2-associated protein | -0.0328905 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0328174 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0326475 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0323061 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0322622 |
| KLF6 | Kruppel-like factor 6 | -0.0322067 |
| B2M | beta-2-microglobulin | -0.0316995 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.031681 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0315542 |
