| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.160381 |
| CD44 | CD44 molecule (Indian blood group) | 0.143831 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.126957 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.120383 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.111044 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.106846 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0931548 |
| SMAD3 | SMAD family member 3 | 0.0837676 |
| SVIL | supervillin | 0.0767926 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0728658 |
| SP100 | SP100 nuclear antigen | 0.0720915 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0718997 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0717843 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.071726 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0709841 |
| MX1 | MX dynamin-like GTPase 1 | 0.0655451 |
| NRP1 | neuropilin 1 | 0.0641623 |
| TMEM178B | transmembrane protein 178B | 0.0627802 |
| FLNB | filamin B, beta | 0.0591446 |
| HMGA2 | high mobility group AT-hook 2 | 0.0574512 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.05708 |
| THBS1 | thrombospondin 1 | 0.0561309 |
| ANXA2 | annexin A2 | 0.055902 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0541805 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0510267 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0491172 |
| MSN | moesin | 0.0490092 |
| SETBP1 | SET binding protein 1 | 0.0476263 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0473661 |
| CLIC4 | chloride intracellular channel 4 | 0.0470091 |
| ENO1 | enolase 1, (alpha) | 0.0467315 |
| FAT1 | FAT atypical cadherin 1 | 0.0460088 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0448513 |
| FLNA | filamin A, alpha | 0.0442096 |
| COL5A3 | collagen, type V, alpha 3 | 0.0425761 |
| EHBP1 | EH domain binding protein 1 | 0.0422633 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0413881 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0406915 |
| PMP22 | peripheral myelin protein 22 | 0.0405842 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0399854 |
| RIGI | RNA sensor RIG-I | 0.0396362 |
| PLSCR1 | phospholipid scramblase 1 | 0.039525 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0393627 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0388932 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0380067 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0354776 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0353594 |
| VCL | vinculin | 0.0351479 |
| UBC | ubiquitin C | 0.0349437 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0348865 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0347117 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0336492 |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.0334396 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0327386 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0319473 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0313977 |
| ASPH | aspartate beta-hydroxylase | 0.0313549 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0310733 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.031051 |
| TGM2 | transglutaminase 2 | 0.0309601 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0309013 |
| RNF213 | ring finger protein 213 | 0.0305956 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0297126 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0295621 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0293945 |
| IFI44L | interferon-induced protein 44-like | 0.0292891 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0280002 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0279314 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0279238 |
| MX2 | MX dynamin-like GTPase 2 | 0.0277926 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0274626 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0272576 |
| ANGPTL4 | angiopoietin-like 4 | 0.0271965 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0271909 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0269168 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0264773 |
| EMP1 | epithelial membrane protein 1 | 0.0262369 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0257375 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0251211 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0250002 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0249946 |
| NID1 | nidogen 1 | 0.0247829 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0245838 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0245506 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0242984 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.023937 |
| GLIS3 | GLIS family zinc finger 3 | 0.0238734 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0238268 |
| ITGA11 | integrin, alpha 11 | 0.0236434 |
| FRMD4A | FERM domain containing 4A | 0.0234508 |
| PLEC | plectin | 0.0233951 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0233201 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0231869 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0229578 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.022861 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0227573 |
| ADAR | adenosine deaminase, RNA-specific | 0.0224739 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0224725 |
| IL6ST | interleukin 6 signal transducer | 0.0224216 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0221586 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | -0.199852 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.187097 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.135315 |
| NDRG1 | N-myc downstream regulated 1 | -0.119768 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.103245 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0980258 |
| MMP12 | matrix metallopeptidase 12 | -0.0976893 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0951093 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0844276 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0839457 |
| COL1A1 | collagen, type I, alpha 1 | -0.0807477 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0803527 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0791645 |
| COL5A1 | collagen, type V, alpha 1 | -0.0674949 |
| CD109 | CD109 molecule | -0.0673512 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0667141 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0641836 |
| TMSB10 | thymosin beta 10 | -0.0639205 |
| GOLGA4 | golgin A4 | -0.0610474 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0600935 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0572706 |
| LOXL2 | lysyl oxidase-like 2 | -0.0572097 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0559778 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.054132 |
| COL6A1 | collagen, type VI, alpha 1 | -0.053737 |
| HM13 | histocompatibility (minor) 13 | -0.0537302 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0527197 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0507552 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0495078 |
| HDLBP | high density lipoprotein binding protein | -0.0491054 |
| CADM1 | cell adhesion molecule 1 | -0.0488998 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0488098 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0468131 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0457473 |
| PCBP3 | poly(rC) binding protein 3 | -0.0454184 |
| TNS3 | tensin 3 | -0.0449069 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0445077 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0437331 |
| SEC24D | SEC24 family member D | -0.0433432 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0428181 |
| RAB2A | RAB2A, member RAS oncogene family | -0.042028 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0415962 |
| MAP4 | microtubule-associated protein 4 | -0.0411215 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0410386 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0404286 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0403321 |
| PGK1 | phosphoglycerate kinase 1 | -0.0391862 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.038919 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0383552 |
| FTL | ferritin, light polypeptide | -0.0379015 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0377349 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0372462 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0368874 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0366859 |
| RND3 | Rho family GTPase 3 | -0.0364559 |
| EGFR | epidermal growth factor receptor | -0.0360115 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0357687 |
| PGM3 | phosphoglucomutase 3 | -0.0357453 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0357381 |
| FNIP1 | folliculin interacting protein 1 | -0.0347426 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0333129 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.0331989 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0330265 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0329956 |
| TMEM165 | transmembrane protein 165 | -0.0328154 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0328012 |
| FBXO32 | F-box protein 32 | -0.0324166 |
| CA12 | carbonic anhydrase XII | -0.0322858 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0322217 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0320482 |
| ANO10 | anoctamin 10 | -0.0319154 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0315537 |
| EGR1 | early growth response 1 | -0.0315453 |
| RHOQ | ras homolog family member Q | -0.0311918 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0310993 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0310121 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0309339 |
| INHBA | inhibin, beta A | -0.0304619 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.030457 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0301343 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0300255 |
| GNAS | GNAS complex locus | -0.0300173 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.029456 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0294358 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0293843 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0292726 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0290405 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0290142 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0287378 |
| ARF4 | ADP-ribosylation factor 4 | -0.0287281 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0285598 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0281723 |
| CDON | cell adhesion associated, oncogene regulated | -0.0280199 |
| SRP54 | signal recognition particle 54kDa | -0.027825 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0278247 |
| PARVB | parvin, beta | -0.027781 |
| MTDH | metadherin | -0.0276536 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0273704 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0268332 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0268109 |
