| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.0835627 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0718337 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0633418 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0575471 |
| TXNRD1 | thioredoxin reductase 1 | 0.0572325 |
| ENO1 | enolase 1, (alpha) | 0.0572305 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0520207 |
| AOPEP | aminopeptidase O (putative) | 0.05138 |
| PDE10A | phosphodiesterase 10A | 0.0478245 |
| CNKSR3 | CNKSR family member 3 | 0.0463159 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.04481 |
| CPE | carboxypeptidase E | 0.0437962 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0432041 |
| FAT1 | FAT atypical cadherin 1 | 0.0409418 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0408623 |
| TMSB4X | thymosin beta 4, X-linked | 0.0395202 |
| SCG2 | secretogranin II | 0.0377971 |
| RIT2 | Ras-like without CAAX 2 | 0.0356318 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0337338 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0328886 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0317892 |
| PLSCR1 | phospholipid scramblase 1 | 0.0315697 |
| CHGB | chromogranin B | 0.0314177 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0311463 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0311134 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0309785 |
| MX2 | MX dynamin-like GTPase 2 | 0.0298684 |
| SP100 | SP100 nuclear antigen | 0.0296582 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0288112 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | 0.0286737 |
| NBEA | neurobeachin | 0.0281297 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0275262 |
| TOX | thymocyte selection-associated high mobility group box | 0.0269131 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0260305 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0259879 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0254704 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0251112 |
| RIGI | RNA sensor RIG-I | 0.0250761 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0250395 |
| KIF26B | kinesin family member 26B | 0.024678 |
| PEX5L | peroxisomal biogenesis factor 5-like | 0.0236647 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0235241 |
| SCG3 | secretogranin III | 0.02347 |
| KCNJ6 | potassium channel, inwardly rectifying subfamily J, member 6 | 0.0223873 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0223571 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0222537 |
| TMEM255B | transmembrane protein 255B | 0.0217827 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0216365 |
| RNF213 | ring finger protein 213 | 0.0215797 |
| WWOX | WW domain containing oxidoreductase | 0.0206387 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | 0.0205883 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | 0.0201452 |
| DOK6 | docking protein 6 | 0.020045 |
| CNTNAP5 | contactin associated protein-like 5 | 0.0200447 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.020044 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.019906 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 | 0.0197722 |
| DSPP | dentin sialophosphoprotein | 0.0194598 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.019299 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0192071 |
| STPG2 | sperm-tail PG-rich repeat containing 2 | 0.01893 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | 0.0187952 |
| DST | dystonin | 0.0186339 |
| HMGB3 | high mobility group box 3 | 0.0183606 |
| EPHA4 | EPH receptor A4 | 0.018207 |
| DUSP10 | dual specificity phosphatase 10 | 0.0181684 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 0.0180392 |
| MTAP | methylthioadenosine phosphorylase | 0.0179417 |
| CHGA | chromogranin A | 0.0178142 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.0176473 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0176465 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0176459 |
| NRP1 | neuropilin 1 | 0.0175778 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0174408 |
| SHTN1 | shootin 1 | 0.0172164 |
| KIAA0825 | KIAA0825 | 0.0167801 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | 0.016681 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0166484 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0165599 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0164859 |
| PMP22 | peripheral myelin protein 22 | 0.0163632 |
| NCKAP5 | NCK-associated protein 5 | 0.016274 |
| UNC5D | unc-5 homolog D (C. elegans) | 0.0162526 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.01619 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.0159488 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0159189 |
| GLCCI1 | glucocorticoid induced 1 | 0.0158476 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0158298 |
| DUSP4 | dual specificity phosphatase 4 | 0.0155054 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0154835 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0154318 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0153331 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0152061 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0150895 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.015088 |
| SVIL | supervillin | 0.0149454 |
| ANKRD26 | ankyrin repeat domain 26 | 0.014924 |
| POU6F2 | POU class 6 homeobox 2 | 0.0148844 |
| ARFGEF3 | ARFGEF family member 3 | 0.0148788 |
| H1-0 | H1.0 linker histone | 0.0147159 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TENM1 | teneurin transmembrane protein 1 | -0.126361 |
| GPC6 | glypican 6 | -0.123128 |
| NDRG1 | N-myc downstream regulated 1 | -0.115908 |
| DTNA | dystrobrevin, alpha | -0.112532 |
| PTMA | prothymosin, alpha | -0.103468 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.100814 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0863449 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0758152 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0733074 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.069727 |
| RORA | RAR-related orphan receptor A | -0.0690218 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0592245 |
| CADM1 | cell adhesion molecule 1 | -0.0583781 |
| CENPF | centromere protein F, 350/400kDa | -0.0575217 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0562741 |
| ESRRG | estrogen-related receptor gamma | -0.0552358 |
| ZNF292 | zinc finger protein 292 | -0.0548394 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0546699 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.05323 |
| EGR1 | early growth response 1 | -0.0498306 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0497949 |
| MSI2 | musashi RNA-binding protein 2 | -0.0494303 |
| MCL1 | myeloid cell leukemia 1 | -0.0469256 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0461349 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0458107 |
| RPS21 | ribosomal protein S21 | -0.045728 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0455527 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.045296 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0431826 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0430957 |
| DENND1A | DENN/MADD domain containing 1A | -0.0424297 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0420353 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0416407 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0406505 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0405848 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0399309 |
| MATR3 | matrin 3 | -0.039609 |
| HOMER1 | homer scaffolding protein 1 | -0.0385988 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0380325 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0379885 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.037695 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0376947 |
| TPD52 | tumor protein D52 | -0.0373384 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.037276 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0370243 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0363824 |
| MED13L | mediator complex subunit 13-like | -0.0362982 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0355011 |
| TTC19 | tetratricopeptide repeat domain 19 | -0.0352432 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0352108 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0352028 |
| NUP58 | nucleoporin 58 | -0.0348974 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0348045 |
| KLHL29 | kelch-like family member 29 | -0.0346459 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0342922 |
| WAC | WW domain containing adaptor with coiled-coil | -0.034176 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.034117 |
| PCBP3 | poly(rC) binding protein 3 | -0.0340622 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0340512 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0337228 |
| POTEF | POTE ankyrin domain family, member F | -0.0335346 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0329578 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0328206 |
| APP | amyloid beta (A4) precursor protein | -0.0328029 |
| JAM3 | junctional adhesion molecule 3 | -0.0325482 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.032479 |
| EXT1 | exostosin glycosyltransferase 1 | -0.032388 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0317761 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0315723 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0312649 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0311903 |
| NOP58 | NOP58 ribonucleoprotein | -0.0310967 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0310188 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0309878 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0309669 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0309212 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0309032 |
| XPO1 | exportin 1 | -0.0305082 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0300614 |
| ONECUT2 | one cut homeobox 2 | -0.0300456 |
| IQSEC1 | IQ motif and Sec7 domain 1 | -0.029983 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0296819 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0296612 |
| VEGFA | vascular endothelial growth factor A | -0.0296412 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0295551 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0294859 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0291923 |
| CALCA | calcitonin-related polypeptide alpha | -0.0289321 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0284727 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0284335 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0283781 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0280497 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0276013 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0275173 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0272394 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0271835 |
| BCL2 | B-cell CLL/lymphoma 2 | -0.0271386 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0270762 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0268573 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0267942 |
