| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG3 | neuregulin 3 | 0.15036 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.10515 |
| DST | dystonin | 0.104372 |
| FMN1 | formin 1 | 0.0980892 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0879486 |
| ENO1 | enolase 1, (alpha) | 0.0840241 |
| FRMD5 | FERM domain containing 5 | 0.0802829 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0693662 |
| FLNA | filamin A, alpha | 0.0690225 |
| RNF213 | ring finger protein 213 | 0.0668134 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0651678 |
| FN1 | fibronectin 1 | 0.0603183 |
| LAMB1 | laminin, beta 1 | 0.0561415 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0559506 |
| RUNX1 | runt-related transcription factor 1 | 0.0540397 |
| SP100 | SP100 nuclear antigen | 0.0538294 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.051933 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0510538 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0509941 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.05072 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0507147 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0495059 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0474928 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0457275 |
| ICAM1 | intercellular adhesion molecule 1 | 0.04569 |
| AMOTL1 | angiomotin like 1 | 0.0453834 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.044863 |
| SFTPA2 | surfactant protein A2 | 0.043732 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0435574 |
| MKI67 | marker of proliferation Ki-67 | 0.0431429 |
| CD44 | CD44 molecule (Indian blood group) | 0.0430123 |
| IFI44L | interferon-induced protein 44-like | 0.0426573 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0419444 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0418013 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0408948 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.040656 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0401487 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0398923 |
| ETV6 | ets variant 6 | 0.0397016 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.039483 |
| RIGI | RNA sensor RIG-I | 0.0381531 |
| TPM3 | tropomyosin 3 | 0.0377737 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0377013 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0376609 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0371848 |
| FUS | FUS RNA binding protein | 0.0369108 |
| FLNB | filamin B, beta | 0.0366488 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.036521 |
| GOLGB1 | golgin B1 | 0.0365071 |
| MSN | moesin | 0.0364674 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0360881 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0358942 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0356517 |
| PLEC | plectin | 0.0351574 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0339798 |
| ASPH | aspartate beta-hydroxylase | 0.0339083 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0335923 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.033477 |
| PLSCR1 | phospholipid scramblase 1 | 0.0334483 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0334279 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0333712 |
| CTSB | cathepsin B | 0.0332136 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0327634 |
| PTK2 | protein tyrosine kinase 2 | 0.0323525 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.032121 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0319182 |
| FRMD4A | FERM domain containing 4A | 0.0315415 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0308321 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0306348 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0306243 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0305565 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0303987 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0303851 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0302733 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0301198 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0300362 |
| MELTF | melanotransferrin | 0.0291572 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0290323 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0288962 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0287289 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0286049 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0285492 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0285032 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0283841 |
| SET | SET nuclear proto-oncogene | 0.0280071 |
| NLGN1 | neuroligin 1 | 0.0276333 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0269911 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0268681 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0267589 |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.026606 |
| FHIT | fragile histidine triad | 0.0265535 |
| SVIL | supervillin | 0.0260141 |
| NRP2 | neuropilin 2 | 0.0258714 |
| MACROD2 | MACRO domain containing 2 | 0.0257861 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0257365 |
| UBC | ubiquitin C | 0.0254903 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0254573 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0252501 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0250463 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0250299 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.204552 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.148729 |
| VIM | vimentin | -0.125754 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0899942 |
| LSAMP | limbic system-associated membrane protein | -0.0874984 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0804531 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0786118 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0780639 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0770694 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0765981 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0755513 |
| GOLGA4 | golgin A4 | -0.0753807 |
| RPL35A | ribosomal protein L35a | -0.06889 |
| RPLP1 | ribosomal protein, large, P1 | -0.0626707 |
| MSI2 | musashi RNA-binding protein 2 | -0.0626297 |
| FTL | ferritin, light polypeptide | -0.0587068 |
| PMEL | premelanosome protein | -0.0559015 |
| MT2A | metallothionein 2A | -0.0547323 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0531281 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0518702 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0493765 |
| RPS3 | ribosomal protein S3 | -0.048915 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0478973 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0469477 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0458557 |
| TMSB10 | thymosin beta 10 | -0.045673 |
| HMGA1 | high mobility group AT-hook 1 | -0.0455319 |
| RPL23 | ribosomal protein L23 | -0.045097 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0425173 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0416835 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0400352 |
| LDHA | lactate dehydrogenase A | -0.0383368 |
| SQSTM1 | sequestosome 1 | -0.0382526 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0382009 |
| NDRG1 | N-myc downstream regulated 1 | -0.0380977 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0366624 |
| POTEF | POTE ankyrin domain family, member F | -0.0358906 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0355862 |
| RPS23 | ribosomal protein S23 | -0.0347359 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0346909 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0341959 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.033996 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0334453 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0332268 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0330587 |
| RPS6 | ribosomal protein S6 | -0.0329518 |
| RPS21 | ribosomal protein S21 | -0.0325548 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0324883 |
| FNIP1 | folliculin interacting protein 1 | -0.0322851 |
| RPL34 | ribosomal protein L34 | -0.032245 |
| MORF4L2 | mortality factor 4 like 2 | -0.0318233 |
| RPS13 | ribosomal protein S13 | -0.0317454 |
| FOXO3 | forkhead box O3 | -0.0311245 |
| POU2F1 | POU class 2 homeobox 1 | -0.0309972 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0306052 |
| SEC24A | SEC24 family member A | -0.0304262 |
| MAP4 | microtubule-associated protein 4 | -0.0303015 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.02992 |
| TKT | transketolase | -0.0296745 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0296563 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0293953 |
| RHOA | ras homolog family member A | -0.0292788 |
| GNAS | GNAS complex locus | -0.029277 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0291084 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0290822 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.028816 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0286982 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.028245 |
| SBF2 | SET binding factor 2 | -0.0281916 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0281532 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0281296 |
| WDR45B | WD repeat domain 45B | -0.0279197 |
| RPL11 | ribosomal protein L11 | -0.0277465 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0275353 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0273946 |
| RTN4 | reticulon 4 | -0.0268183 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.026729 |
| TFRC | transferrin receptor | -0.0266842 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0266583 |
| FAM13B | family with sequence similarity 13, member B | -0.0264978 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0261793 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0257787 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | -0.0255971 |
| FILIP1 | filamin A interacting protein 1 | -0.0254911 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.025491 |
| PGK1 | phosphoglycerate kinase 1 | -0.0253204 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0252278 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0249341 |
| RPS20 | ribosomal protein S20 | -0.0249336 |
| STK10 | serine/threonine kinase 10 | -0.0249266 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0247046 |
| RPL28 | ribosomal protein L28 | -0.0245506 |
| RPL32 | ribosomal protein L32 | -0.0245206 |
| HELZ | helicase with zinc finger | -0.0244812 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0244481 |
| SNU13 | small nuclear ribonucleoprotein 13 | -0.0242825 |
| COG5 | component of oligomeric golgi complex 5 | -0.0239831 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0239678 |
| ATXN2 | ataxin 2 | -0.0239548 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0236851 |
