| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.105136 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0870364 |
| MKI67 | marker of proliferation Ki-67 | 0.0817086 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0777796 |
| MACROD2 | MACRO domain containing 2 | 0.0698026 |
| NAV2 | neuron navigator 2 | 0.0559713 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0518878 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0511683 |
| CENPF | centromere protein F, 350/400kDa | 0.0498224 |
| ENO1 | enolase 1, (alpha) | 0.0486002 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0469126 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0467221 |
| BMP10 | bone morphogenetic protein 10 | 0.0465491 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0437824 |
| PKM | pyruvate kinase, muscle | 0.0405286 |
| GLI3 | GLI family zinc finger 3 | 0.0388885 |
| RPL3 | ribosomal protein L3 | 0.0386305 |
| RRM2 | ribonucleotide reductase M2 | 0.0377125 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0375457 |
| DIAPH3 | diaphanous-related formin 3 | 0.0368557 |
| MYO5C | myosin VC | 0.0362726 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0334345 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0331127 |
| GSE1 | Gse1 coiled-coil protein | 0.0325264 |
| PRELID2 | PRELI domain containing 2 | 0.032352 |
| ITGA6 | integrin, alpha 6 | 0.0313644 |
| PCBP2 | poly(rC) binding protein 2 | 0.0310709 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.031051 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0310266 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.030444 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0303554 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0301487 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0298141 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0295321 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0293863 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0276943 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0271715 |
| XPO1 | exportin 1 | 0.0268835 |
| POTEF | POTE ankyrin domain family, member F | 0.0267261 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.026039 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0255204 |
| TPM3 | tropomyosin 3 | 0.0249293 |
| KIF5C | kinesin family member 5C | 0.024885 |
| PCM1 | pericentriolar material 1 | 0.0246918 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0244782 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0244718 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0243746 |
| HSPA8 | heat shock 70kDa protein 8 | 0.02433 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0243212 |
| HJURP | Holliday junction recognition protein | 0.023527 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 0.0234026 |
| KIF11 | kinesin family member 11 | 0.0233305 |
| FN1 | fibronectin 1 | 0.0230741 |
| FAT1 | FAT atypical cadherin 1 | 0.0229882 |
| TPX2 | TPX2, microtubule-associated | 0.0228746 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0228049 |
| ANKRD36 | ankyrin repeat domain 36 | 0.022782 |
| PTMS | parathymosin | 0.0227592 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.0224213 |
| LONRF2 | LON peptidase N-terminal domain and ring finger 2 | 0.0223469 |
| KIF5B | kinesin family member 5B | 0.0223137 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0222216 |
| TPM4 | tropomyosin 4 | 0.0220615 |
| CENPE | centromere protein E, 312kDa | 0.021948 |
| KIF23 | kinesin family member 23 | 0.0217813 |
| CCDC88A | coiled-coil domain containing 88A | 0.0216087 |
| TMPO | thymopoietin | 0.0215712 |
| CEP112 | centrosomal protein 112kDa | 0.0215097 |
| SEPTIN9 | septin 9 | 0.0213909 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0212883 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.02127 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0209404 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0207858 |
| ANLN | anillin, actin binding protein | 0.0206545 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0205641 |
| CEP128 | centrosomal protein 128kDa | 0.0205495 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0203276 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0202339 |
| MMS22L | MMS22-like, DNA repair protein | 0.0201101 |
| H1-4 | H1.4 linker histone, cluster member | 0.0201035 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0198978 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0198568 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0196351 |
| RPL21 | ribosomal protein L21 | 0.0195199 |
| HELZ | helicase with zinc finger | 0.0195092 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0194009 |
| WWOX | WW domain containing oxidoreductase | 0.0193505 |
| KNL1 | kinetochore scaffold 1 | 0.0193375 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.019323 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0192958 |
| TJP1 | tight junction protein 1 | 0.0191478 |
| SSH2 | slingshot protein phosphatase 2 | 0.019123 |
| AHNAK | AHNAK nucleoprotein | 0.0191078 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 0.0188345 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0186665 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0184143 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 0.0183444 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0181819 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.018088 |
| GSPT1 | G1 to S phase transition 1 | 0.0180128 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.202286 |
| PTMA | prothymosin, alpha | -0.150806 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14458 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.121634 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0978484 |
| ANK2 | ankyrin 2, neuronal | -0.0973042 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0957573 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0860136 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0855793 |
| RTN4 | reticulon 4 | -0.0850889 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0815286 |
| GOLGA4 | golgin A4 | -0.0805 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0803294 |
| S100A6 | S100 calcium binding protein A6 | -0.0772528 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0766493 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0761225 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0711663 |
| LDHA | lactate dehydrogenase A | -0.0702699 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0699576 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0685355 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0684814 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0674851 |
| VCL | vinculin | -0.0670081 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0664869 |
| RPL35A | ribosomal protein L35a | -0.0646971 |
| HDLBP | high density lipoprotein binding protein | -0.063827 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0629456 |
| TMEM41B | transmembrane protein 41B | -0.0596258 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0584986 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0570841 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0567205 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0550481 |
| TMSB4X | thymosin beta 4, X-linked | -0.0546351 |
| ANKRD11 | ankyrin repeat domain 11 | -0.054244 |
| ACTG1 | actin gamma 1 | -0.0541457 |
| RPS6 | ribosomal protein S6 | -0.0536401 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0529297 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0524413 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0520933 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0509489 |
| COG5 | component of oligomeric golgi complex 5 | -0.0508175 |
| RBM39 | RNA binding motif protein 39 | -0.0507168 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0507068 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.050214 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0498474 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0489581 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0471873 |
| RRBP1 | ribosome binding protein 1 | -0.0471579 |
| EGFR | epidermal growth factor receptor | -0.0462197 |
| JMJD1C | jumonji domain containing 1C | -0.0453657 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0453316 |
| RPL11 | ribosomal protein L11 | -0.0449826 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.043941 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0433893 |
| AHI1 | Abelson helper integration site 1 | -0.0425927 |
| SQSTM1 | sequestosome 1 | -0.0422855 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0419344 |
| SEC24D | SEC24 family member D | -0.0415581 |
| FBXO11 | F-box protein 11 | -0.0414367 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0414334 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0408693 |
| RHBDD1 | rhomboid domain containing 1 | -0.0408084 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0406293 |
| NBEA | neurobeachin | -0.0405362 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0404499 |
| FLNB | filamin B, beta | -0.0401425 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0397283 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0387947 |
| RPS23 | ribosomal protein S23 | -0.0386186 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.038421 |
| RPS24 | ribosomal protein S24 | -0.0382164 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0378682 |
| PHF3 | PHD finger protein 3 | -0.0378123 |
| OSMR | oncostatin M receptor | -0.0372924 |
| FOXP1 | forkhead box P1 | -0.0371311 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0370225 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0367887 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0358878 |
| CDK13 | cyclin-dependent kinase 13 | -0.035879 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0358396 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0357417 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0356759 |
| HLA-B | major histocompatibility complex, class I, B | -0.0356645 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0356369 |
| PHF14 | PHD finger protein 14 | -0.0355822 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0354396 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0350977 |
| HM13 | histocompatibility (minor) 13 | -0.034851 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0344342 |
| YARS1 | tyrosyl-tRNA synthetase 1 | -0.0343639 |
| RPL9 | ribosomal protein L9 | -0.0340738 |
| CCND1 | cyclin D1 | -0.0338929 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0337364 |
| RPL13A | ribosomal protein L13a | -0.0333889 |
| PYGB | phosphorylase, glycogen; brain | -0.0332733 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0331947 |
| ZNF217 | zinc finger protein 217 | -0.0325057 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0324072 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0322158 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0320006 |
