| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.249976 |
| COL6A3 | collagen, type VI, alpha 3 | 0.224191 |
| GLIS3 | GLIS family zinc finger 3 | 0.177366 |
| VCAN | versican | 0.172116 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.168094 |
| BICC1 | BicC family RNA binding protein 1 | 0.112669 |
| ADM | adrenomedullin | 0.105131 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0830329 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0773332 |
| GPC6 | glypican 6 | 0.0732481 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0722098 |
| CTSB | cathepsin B | 0.0655034 |
| SFTPA2 | surfactant protein A2 | 0.0632688 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0611174 |
| VMP1 | vacuole membrane protein 1 | 0.0556063 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0541574 |
| C3 | complement component 3 | 0.0539168 |
| JUN | jun proto-oncogene | 0.0486033 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0469708 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0461072 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0442108 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0422356 |
| FRMD4A | FERM domain containing 4A | 0.0416666 |
| TXNIP | thioredoxin interacting protein | 0.0409774 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0403683 |
| VEGFA | vascular endothelial growth factor A | 0.0398047 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0388445 |
| DST | dystonin | 0.0375978 |
| RAI14 | retinoic acid induced 14 | 0.0375175 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0369023 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.036327 |
| NDRG1 | N-myc downstream regulated 1 | 0.0353317 |
| HMGA2 | high mobility group AT-hook 2 | 0.0340476 |
| HDAC9 | histone deacetylase 9 | 0.0339087 |
| TNS3 | tensin 3 | 0.0338134 |
| PMP22 | peripheral myelin protein 22 | 0.0336451 |
| TENM2 | teneurin transmembrane protein 2 | 0.0330577 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0326103 |
| CCNL1 | cyclin L1 | 0.032324 |
| ANO6 | anoctamin 6 | 0.0322393 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0319452 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0316845 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.031649 |
| EHBP1 | EH domain binding protein 1 | 0.0309848 |
| BRD2 | bromodomain containing 2 | 0.0306245 |
| THBS2 | thrombospondin 2 | 0.030174 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0301688 |
| ENO1 | enolase 1, (alpha) | 0.0299513 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0294802 |
| UBC | ubiquitin C | 0.0291814 |
| BPTF | bromodomain PHD finger transcription factor | 0.0290393 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0285265 |
| EGR1 | early growth response 1 | 0.0283125 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.028035 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0279957 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0279528 |
| THBS1 | thrombospondin 1 | 0.0278947 |
| RNF213 | ring finger protein 213 | 0.027824 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0278155 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0275746 |
| TMEM132D | transmembrane protein 132D | 0.0272723 |
| FLNA | filamin A, alpha | 0.0272174 |
| ASPH | aspartate beta-hydroxylase | 0.0261971 |
| HLA-E | major histocompatibility complex, class I, E | 0.0260815 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0259176 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0254844 |
| LOX | lysyl oxidase | 0.0254341 |
| FTL | ferritin, light polypeptide | 0.0253671 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0253596 |
| COL5A1 | collagen, type V, alpha 1 | 0.0253488 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0251589 |
| LAMB1 | laminin, beta 1 | 0.0249884 |
| MSN | moesin | 0.0245209 |
| FLNB | filamin B, beta | 0.0244026 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0241862 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0240931 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0237057 |
| MLPH | melanophilin | 0.0236145 |
| STC2 | stanniocalcin 2 | 0.0235554 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0234962 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0233315 |
| FMNL2 | formin-like 2 | 0.0231632 |
| TRAM2 | translocation associated membrane protein 2 | 0.023128 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0227685 |
| GOLGB1 | golgin B1 | 0.0223344 |
| EGFR | epidermal growth factor receptor | 0.0219336 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0217937 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0215399 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0213629 |
| PRICKLE2 | prickle homolog 2 (Drosophila) | 0.0211652 |
| SVIL | supervillin | 0.021094 |
| CTSA | cathepsin A | 0.0210061 |
| PLK2 | polo-like kinase 2 | 0.0208795 |
| RASAL2 | RAS protein activator like 2 | 0.0208166 |
| ZNF608 | zinc finger protein 608 | 0.0207987 |
| ATXN1 | ataxin 1 | 0.0205163 |
| FHIT | fragile histidine triad | 0.0204739 |
| WFDC10B | WAP four-disulfide core domain 10B | 0.0204522 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0202742 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0200548 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.14497 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.144089 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.114702 |
| NAV2 | neuron navigator 2 | -0.10296 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0948675 |
| RPS24 | ribosomal protein S24 | -0.0808708 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0786477 |
| TMSB10 | thymosin beta 10 | -0.0741728 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0694819 |
| FN1 | fibronectin 1 | -0.0686259 |
| RPL23 | ribosomal protein L23 | -0.0649247 |
| CENPF | centromere protein F, 350/400kDa | -0.0585744 |
| RPL35A | ribosomal protein L35a | -0.0569396 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0565868 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0551627 |
| ANLN | anillin, actin binding protein | -0.0548037 |
| CADM1 | cell adhesion molecule 1 | -0.0547686 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0547075 |
| WTAP | Wilms tumor 1 associated protein | -0.05406 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0534888 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0513073 |
| SPAG9 | sperm associated antigen 9 | -0.0489198 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0481354 |
| HLA-B | major histocompatibility complex, class I, B | -0.0481148 |
| RPL26 | ribosomal protein L26 | -0.0479335 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0478204 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0468228 |
| FOXO3 | forkhead box O3 | -0.0444061 |
| ACTG1 | actin gamma 1 | -0.0435022 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0432395 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0421428 |
| MKI67 | marker of proliferation Ki-67 | -0.0420178 |
| MT2A | metallothionein 2A | -0.0418696 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0409648 |
| MORF4L2 | mortality factor 4 like 2 | -0.0399189 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0397533 |
| GNAS | GNAS complex locus | -0.0391953 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0385575 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0381886 |
| PGK1 | phosphoglycerate kinase 1 | -0.0381654 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0381584 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0381569 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0381225 |
| KLF6 | Kruppel-like factor 6 | -0.0374672 |
| RPLP1 | ribosomal protein, large, P1 | -0.0365493 |
| DEK | DEK proto-oncogene | -0.036234 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0360059 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0357374 |
| FNIP1 | folliculin interacting protein 1 | -0.0356249 |
| SRGN | serglycin | -0.0354954 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0351641 |
| DENND5A | DENN/MADD domain containing 5A | -0.0350903 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0347718 |
| LDHA | lactate dehydrogenase A | -0.0346739 |
| KIF4A | kinesin family member 4A | -0.0342331 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0341062 |
| RPL27A | ribosomal protein L27a | -0.0337541 |
| RPS21 | ribosomal protein S21 | -0.033729 |
| RPLP0 | ribosomal protein, large, P0 | -0.0330173 |
| RPS4X | ribosomal protein S4, X-linked | -0.0321184 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0319802 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0314763 |
| HMGA1 | high mobility group AT-hook 1 | -0.0313532 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0313185 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0306621 |
| TUBB | tubulin, beta class I | -0.0304575 |
| RTN4 | reticulon 4 | -0.0295189 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0292049 |
| OSMR | oncostatin M receptor | -0.0290744 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.02886 |
| NUP98 | nucleoporin 98kDa | -0.0286721 |
| LOXL2 | lysyl oxidase-like 2 | -0.0283644 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0282628 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0279112 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.027873 |
| RPL34 | ribosomal protein L34 | -0.0277362 |
| TPX2 | TPX2, microtubule-associated | -0.0277066 |
| KLHL5 | kelch-like family member 5 | -0.0276232 |
| RPS8 | ribosomal protein S8 | -0.0270497 |
| HM13 | histocompatibility (minor) 13 | -0.0268303 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0267699 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0267582 |
| RASA2 | RAS p21 protein activator 2 | -0.0266107 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0265076 |
| DIAPH3 | diaphanous-related formin 3 | -0.026455 |
| TAPBP | TAP binding protein (tapasin) | -0.0264082 |
| PRR11 | proline rich 11 | -0.0263194 |
| RBM39 | RNA binding motif protein 39 | -0.0263134 |
| NGLY1 | N-glycanase 1 | -0.0260094 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0259466 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0259018 |
| PTMA | prothymosin, alpha | -0.0258943 |
| CDH13 | cadherin 13 | -0.0258664 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0257889 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0257398 |
| RPS23 | ribosomal protein S23 | -0.0257287 |
| TSC22D2 | TSC22 domain family, member 2 | -0.025684 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0255695 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0254844 |
| KYNU | kynureninase | -0.0252534 |
