| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.205257 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.116386 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0857242 |
| FN1 | fibronectin 1 | 0.0852984 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0762615 |
| HMGA2 | high mobility group AT-hook 2 | 0.0736561 |
| GLIS3 | GLIS family zinc finger 3 | 0.0726246 |
| CD44 | CD44 molecule (Indian blood group) | 0.0704488 |
| VCL | vinculin | 0.0598266 |
| FLNA | filamin A, alpha | 0.0581731 |
| IGF2 | insulin-like growth factor 2 | 0.0570365 |
| CDH13 | cadherin 13 | 0.0550122 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0526997 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0525362 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0509584 |
| EXOC4 | exocyst complex component 4 | 0.0497743 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.049489 |
| RASAL2 | RAS protein activator like 2 | 0.0490418 |
| FAT1 | FAT atypical cadherin 1 | 0.0486959 |
| HDAC9 | histone deacetylase 9 | 0.0485759 |
| ASPH | aspartate beta-hydroxylase | 0.04836 |
| PRELID2 | PRELI domain containing 2 | 0.0472514 |
| KYNU | kynureninase | 0.0469782 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0455052 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0442017 |
| CDK6 | cyclin-dependent kinase 6 | 0.0441355 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0440299 |
| THBS1 | thrombospondin 1 | 0.0435848 |
| TNS3 | tensin 3 | 0.0435778 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0430884 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0423381 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0422325 |
| INTS6 | integrator complex subunit 6 | 0.0391992 |
| CALD1 | caldesmon 1 | 0.0385759 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0378368 |
| MYOF | myoferlin | 0.0377024 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.037428 |
| SETBP1 | SET binding protein 1 | 0.0367366 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0366198 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.036163 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0336058 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0324601 |
| ERBIN | erbb2 interacting protein | 0.0322006 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0319062 |
| RAD51B | RAD51 paralog B | 0.0313678 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0301895 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0293232 |
| PTK2 | protein tyrosine kinase 2 | 0.0288589 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0288444 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0287864 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0286796 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0286386 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0281481 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0271883 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0271541 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0269924 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0268533 |
| EFNA5 | ephrin-A5 | 0.0265169 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0264706 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0264466 |
| FMNL2 | formin-like 2 | 0.0262658 |
| C3 | complement component 3 | 0.0261845 |
| NAV1 | neuron navigator 1 | 0.0257416 |
| RIGI | RNA sensor RIG-I | 0.0253565 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.025263 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0250889 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0249589 |
| ZNF638 | zinc finger protein 638 | 0.0248878 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0246083 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0243969 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0243482 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0243253 |
| VEGFC | vascular endothelial growth factor C | 0.0242885 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0242594 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0238369 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0236854 |
| PDGFC | platelet derived growth factor C | 0.0236446 |
| EHBP1 | EH domain binding protein 1 | 0.0235399 |
| SYNPO | synaptopodin | 0.0232938 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0231589 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0229484 |
| CUX1 | cut-like homeobox 1 | 0.0226972 |
| METTL15 | methyltransferase like 15 | 0.022495 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.022244 |
| PCM1 | pericentriolar material 1 | 0.0222288 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0222091 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0221693 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0218669 |
| RAI14 | retinoic acid induced 14 | 0.0208049 |
| MKI67 | marker of proliferation Ki-67 | 0.0207834 |
| TJP1 | tight junction protein 1 | 0.0207689 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0207583 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.02074 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0205216 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0203277 |
| DUSP6 | dual specificity phosphatase 6 | 0.0203241 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.020315 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0202721 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0202569 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0202552 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.264063 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.217604 |
| B2M | beta-2-microglobulin | -0.164929 |
| MT2A | metallothionein 2A | -0.130734 |
| HLA-B | major histocompatibility complex, class I, B | -0.128829 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.114158 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.101417 |
| TMSB10 | thymosin beta 10 | -0.095903 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0801314 |
| NDRG1 | N-myc downstream regulated 1 | -0.0751814 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0724023 |
| GOLGA4 | golgin A4 | -0.0714235 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0686592 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0663343 |
| ARRDC3 | arrestin domain containing 3 | -0.0635176 |
| PGK1 | phosphoglycerate kinase 1 | -0.0634979 |
| TMEM165 | transmembrane protein 165 | -0.0625439 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0611927 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0597963 |
| VIM | vimentin | -0.0567095 |
| PTMA | prothymosin, alpha | -0.0555423 |
| FTL | ferritin, light polypeptide | -0.0545841 |
| CANX | calnexin | -0.0542769 |
| HLA-C | major histocompatibility complex, class I, C | -0.0535775 |
| H3-3B | H3.3 histone B | -0.0525776 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0522052 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0488085 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0486333 |
| SDC4 | syndecan 4 | -0.0485262 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0478594 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0476587 |
| CALR | calreticulin | -0.047405 |
| ZNF395 | zinc finger protein 395 | -0.047277 |
| SEC24D | SEC24 family member D | -0.0470447 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0467483 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.046366 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0459255 |
| STC1 | stanniocalcin 1 | -0.044285 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0438881 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0438244 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0418205 |
| LDHA | lactate dehydrogenase A | -0.0416248 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0415587 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0414293 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0411669 |
| PKM | pyruvate kinase, muscle | -0.0407437 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0405878 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.040234 |
| FAM13A | family with sequence similarity 13, member A | -0.0401573 |
| NOP58 | NOP58 ribonucleoprotein | -0.0398883 |
| SRP54 | signal recognition particle 54kDa | -0.0394394 |
| TFG | TRK-fused gene | -0.0370994 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.037058 |
| CADM1 | cell adhesion molecule 1 | -0.0369608 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0360626 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0358969 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0352281 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0344691 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0337282 |
| PTGES2 | prostaglandin E synthase 2 | -0.033536 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0333442 |
| LOX | lysyl oxidase | -0.0330608 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.032954 |
| SEC24A | SEC24 family member A | -0.0322558 |
| SUCO | SUN domain containing ossification factor | -0.0322384 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0320605 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0319009 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0316818 |
| RBM39 | RNA binding motif protein 39 | -0.0316272 |
| COL1A2 | collagen, type I, alpha 2 | -0.031514 |
| GNAS | GNAS complex locus | -0.0314852 |
| SETD5 | SET domain containing 5 | -0.0312352 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.030998 |
| CLINT1 | clathrin interactor 1 | -0.0309768 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0308095 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0306522 |
| RPL34 | ribosomal protein L34 | -0.0303862 |
| RPL35A | ribosomal protein L35a | -0.0302514 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0293735 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0293288 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0292435 |
| S100A6 | S100 calcium binding protein A6 | -0.0292326 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0291596 |
| COPA | coatomer protein complex, subunit alpha | -0.0291506 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0286346 |
| GLG1 | golgi glycoprotein 1 | -0.0281085 |
| RINT1 | RAD50 interactor 1 | -0.0276032 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0275166 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0274168 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0274139 |
| HDLBP | high density lipoprotein binding protein | -0.0272685 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0266427 |
| MYADM | myeloid-associated differentiation marker | -0.0261266 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0257956 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0255691 |
| ANXA5 | annexin A5 | -0.0255025 |
| ANXA2 | annexin A2 | -0.0254249 |
| TXNIP | thioredoxin interacting protein | -0.02535 |
| CD99 | CD99 molecule | -0.0252468 |
| SEPTIN7 | septin 7 | -0.0252148 |
