| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.141226 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.126793 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0978529 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0899839 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0872122 |
| DST | dystonin | 0.0839962 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0753793 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.067385 |
| EGFR | epidermal growth factor receptor | 0.064929 |
| HMGA2 | high mobility group AT-hook 2 | 0.0636894 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0609786 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0565412 |
| NAV2 | neuron navigator 2 | 0.0563817 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0557367 |
| PRKCA | protein kinase C, alpha | 0.0549452 |
| FLNA | filamin A, alpha | 0.0526504 |
| PCED1B | PC-esterase domain containing 1B | 0.0526033 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0515584 |
| SMAD3 | SMAD family member 3 | 0.048056 |
| CD44 | CD44 molecule (Indian blood group) | 0.0479006 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.047461 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0473375 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0465038 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0458388 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0441982 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0425532 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0420979 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0420559 |
| LAMB1 | laminin, beta 1 | 0.0420152 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0416864 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0408679 |
| FMNL2 | formin-like 2 | 0.0405812 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0405703 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0401157 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0398149 |
| INTS6 | integrator complex subunit 6 | 0.039055 |
| LMO7 | LIM domain 7 | 0.0387582 |
| CUX1 | cut-like homeobox 1 | 0.0367835 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0367067 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0361048 |
| COL5A1 | collagen, type V, alpha 1 | 0.0359423 |
| SVIL | supervillin | 0.0359119 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0352836 |
| RAI14 | retinoic acid induced 14 | 0.0348886 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0340546 |
| ATXN1 | ataxin 1 | 0.0339897 |
| CCDC88A | coiled-coil domain containing 88A | 0.0335629 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0329347 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0328017 |
| AHNAK | AHNAK nucleoprotein | 0.0327995 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.032783 |
| KIAA1671 | KIAA1671 | 0.0322766 |
| PTK2 | protein tyrosine kinase 2 | 0.0321728 |
| POTEF | POTE ankyrin domain family, member F | 0.0321318 |
| FN1 | fibronectin 1 | 0.032022 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0318706 |
| ENO1 | enolase 1, (alpha) | 0.0317842 |
| ANGPTL4 | angiopoietin-like 4 | 0.0314622 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0313664 |
| PRSS23 | protease, serine, 23 | 0.0313132 |
| UBC | ubiquitin C | 0.0312871 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.031019 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.030895 |
| TXNIP | thioredoxin interacting protein | 0.0306408 |
| RNF217 | ring finger protein 217 | 0.0305605 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0303853 |
| MYO9B | myosin IXB | 0.0302629 |
| ZFHX3 | zinc finger homeobox 3 | 0.0299712 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0291651 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.029041 |
| EXOC4 | exocyst complex component 4 | 0.0288462 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0287747 |
| CAVIN1 | caveolae associated protein 1 | 0.0287608 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.028726 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0286762 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0285052 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0283312 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0283225 |
| THBS1 | thrombospondin 1 | 0.0282581 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0281112 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0279916 |
| ABR | active BCR-related | 0.0278515 |
| ANO6 | anoctamin 6 | 0.0275278 |
| HPCAL1 | hippocalcin-like 1 | 0.0274239 |
| ACTN1 | actinin, alpha 1 | 0.0272216 |
| SYNJ2 | synaptojanin 2 | 0.0269622 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0268456 |
| ANXA2 | annexin A2 | 0.0264296 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0263778 |
| VCL | vinculin | 0.0262414 |
| PLEK2 | pleckstrin 2 | 0.0262108 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0259625 |
| JUN | jun proto-oncogene | 0.0258738 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0256507 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0256413 |
| TLE4 | transducin-like enhancer of split 4 | 0.0255933 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0255636 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0255595 |
| CLIC4 | chloride intracellular channel 4 | 0.0255445 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0254498 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.133401 |
| SMYD3 | SET and MYND domain containing 3 | -0.0894822 |
| DSCAM | Down syndrome cell adhesion molecule | -0.082821 |
| ZNF292 | zinc finger protein 292 | -0.0725762 |
| GOLGA4 | golgin A4 | -0.0716135 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0666015 |
| DEK | DEK proto-oncogene | -0.0627236 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0620559 |
| VIM | vimentin | -0.0608274 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0603692 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0589538 |
| COG5 | component of oligomeric golgi complex 5 | -0.057007 |
| LDHA | lactate dehydrogenase A | -0.0559799 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0539855 |
| PTMA | prothymosin, alpha | -0.0536517 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0536095 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0531949 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0531599 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0528083 |
| RPL35A | ribosomal protein L35a | -0.0519416 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0514665 |
| RPL23 | ribosomal protein L23 | -0.050495 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.050045 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0498296 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0496746 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0496246 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0492403 |
| TMSB10 | thymosin beta 10 | -0.0483013 |
| FNIP1 | folliculin interacting protein 1 | -0.0482902 |
| CANX | calnexin | -0.0481512 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0479349 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0478732 |
| RPLP1 | ribosomal protein, large, P1 | -0.0474833 |
| ECT2 | epithelial cell transforming 2 | -0.0469949 |
| KIAA1958 | KIAA1958 | -0.0469467 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0466736 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0466558 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0466189 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0454425 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0454033 |
| SNX14 | sorting nexin 14 | -0.0444576 |
| TMEM123 | transmembrane protein 123 | -0.0443549 |
| TXNRD1 | thioredoxin reductase 1 | -0.0428622 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0426333 |
| NUP58 | nucleoporin 58 | -0.0419892 |
| LOC112694756 | uncharaterized LOC112694756 | -0.041932 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0410733 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0409377 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0404999 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0403603 |
| RACK1 | receptor for activated C kinase 1 | -0.0397126 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0388863 |
| MATR3 | matrin 3 | -0.0388207 |
| HM13 | histocompatibility (minor) 13 | -0.03829 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0382528 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0377562 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0375333 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0373376 |
| NUP98 | nucleoporin 98kDa | -0.0369692 |
| RPLP0 | ribosomal protein, large, P0 | -0.0368096 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0367272 |
| RBM39 | RNA binding motif protein 39 | -0.0366022 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0362419 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0361824 |
| HDLBP | high density lipoprotein binding protein | -0.0356477 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0354422 |
| RPL4 | ribosomal protein L4 | -0.0352998 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0351222 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0350197 |
| NOP58 | NOP58 ribonucleoprotein | -0.0349891 |
| GNAS | GNAS complex locus | -0.0349064 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0347724 |
| ATM | ATM serine/threonine kinase | -0.0345688 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0344993 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0343897 |
| CLTC | clathrin, heavy chain (Hc) | -0.0342448 |
| CEP95 | centrosomal protein 95kDa | -0.0339571 |
| RPL30 | ribosomal protein L30 | -0.0338959 |
| PHF20 | PHD finger protein 20 | -0.033857 |
| RNF145 | ring finger protein 145 | -0.0337231 |
| CENPF | centromere protein F, 350/400kDa | -0.0337035 |
| TNPO1 | transportin 1 | -0.033676 |
| RPL12 | ribosomal protein L12 | -0.0336747 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0329904 |
| TCERG1 | transcription elongation regulator 1 | -0.0327895 |
| SETD5 | SET domain containing 5 | -0.0327534 |
| SRP54 | signal recognition particle 54kDa | -0.0327477 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0327299 |
| MT2A | metallothionein 2A | -0.0325381 |
| YAP1 | Yes-associated protein 1 | -0.0323636 |
| RRBP1 | ribosome binding protein 1 | -0.0323198 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0323063 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0322826 |
| RPL37A | ribosomal protein L37a | -0.0321606 |
| XPO1 | exportin 1 | -0.0320496 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0319097 |
| YBX3 | Y box binding protein 3 | -0.031868 |
| ANLN | anillin, actin binding protein | -0.0318337 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0316104 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0314408 |
