| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.082983 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0605492 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.03677 |
| FLNA | filamin A, alpha | 0.03247 |
| FN1 | fibronectin 1 | 0.0296971 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0289162 |
| SVIL | supervillin | 0.0264638 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0252585 |
| RNF213 | ring finger protein 213 | 0.0242211 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0225721 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.022019 |
| EMP1 | epithelial membrane protein 1 | 0.0215197 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.021518 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0214712 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0211927 |
| AHR | aryl hydrocarbon receptor | 0.0205477 |
| PLEC | plectin | 0.0203009 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0199913 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0193736 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0192614 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0192058 |
| DNMBP | dynamin binding protein | 0.0191585 |
| EZR | ezrin | 0.0191247 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0178492 |
| CAB39 | calcium binding protein 39 | 0.0178132 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0178087 |
| THBS1 | thrombospondin 1 | 0.0176029 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0167921 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0166697 |
| FAT1 | FAT atypical cadherin 1 | 0.0166071 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0162165 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0158655 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0156985 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0149027 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0148397 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0145063 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0144899 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0142052 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0140281 |
| SIRT1 | sirtuin 1 | 0.0139783 |
| DST | dystonin | 0.013598 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0135079 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0134291 |
| LAMA4 | laminin, alpha 4 | 0.0127775 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0126846 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0125672 |
| VCAN | versican | 0.0125532 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0124942 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0124025 |
| LAMB1 | laminin, beta 1 | 0.012105 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0120773 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0120245 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0119677 |
| IL6ST | interleukin 6 signal transducer | 0.0118971 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0117454 |
| STK17B | serine/threonine kinase 17b | 0.0117102 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0116751 |
| DUSP10 | dual specificity phosphatase 10 | 0.0116702 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0114752 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0114198 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0113338 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0111892 |
| JAG1 | jagged 1 | 0.0111085 |
| CD44 | CD44 molecule (Indian blood group) | 0.0110568 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0109659 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0108566 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0107212 |
| EREG | epiregulin | 0.0105897 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0105835 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0105827 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0105441 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0104505 |
| PER2 | period circadian clock 2 | 0.0103245 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0102182 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0101451 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0101027 |
| UBC | ubiquitin C | 0.00998978 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00994225 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.00992851 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00992103 |
| ARRDC3 | arrestin domain containing 3 | 0.00980291 |
| AREG | amphiregulin | 0.00975194 |
| IL6R | interleukin 6 receptor | 0.0095434 |
| RAB27B | RAB27B, member RAS oncogene family | 0.00951939 |
| PLEKHH2 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 | 0.00950383 |
| GOLM1 | golgi membrane protein 1 | 0.00926129 |
| MX1 | MX dynamin-like GTPase 1 | 0.00911255 |
| KIAA1217 | KIAA1217 | 0.00903356 |
| ITGA6 | integrin, alpha 6 | 0.00902634 |
| PCDH7 | protocadherin 7 | 0.00900516 |
| PLPP3 | phospholipid phosphatase 3 | 0.00892904 |
| ATF3 | activating transcription factor 3 | 0.00892774 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00890214 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00889133 |
| DUSP5 | dual specificity phosphatase 5 | 0.00889047 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00887995 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00881637 |
| IFI44L | interferon-induced protein 44-like | 0.00878802 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.00872861 |
| SLK | STE20-like kinase | 0.00860908 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.300198 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.265115 |
| NRG1 | neuregulin 1 | -0.171796 |
| PTMA | prothymosin, alpha | -0.12345 |
| TMSB10 | thymosin beta 10 | -0.116447 |
| SQSTM1 | sequestosome 1 | -0.110874 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.110205 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.10772 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0921807 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0824564 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0783567 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0777072 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0762724 |
| HLA-B | major histocompatibility complex, class I, B | -0.073869 |
| S100A6 | S100 calcium binding protein A6 | -0.0722369 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0700331 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0668102 |
| FTL | ferritin, light polypeptide | -0.0648356 |
| TMEM165 | transmembrane protein 165 | -0.0636606 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.06018 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0600091 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0599382 |
| ITGA1 | integrin, alpha 1 | -0.0589936 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0567235 |
| CANX | calnexin | -0.0563206 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0563128 |
| VCL | vinculin | -0.0558815 |
| GLIS3 | GLIS family zinc finger 3 | -0.0535501 |
| TMSB4X | thymosin beta 4, X-linked | -0.053103 |
| HMGA2 | high mobility group AT-hook 2 | -0.0529818 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0507519 |
| B2M | beta-2-microglobulin | -0.0495912 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0481626 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0465537 |
| PLIN2 | perilipin 2 | -0.0463768 |
| EFNA5 | ephrin-A5 | -0.0452851 |
| NDRG1 | N-myc downstream regulated 1 | -0.0451467 |
| PKM | pyruvate kinase, muscle | -0.043822 |
| VIM | vimentin | -0.0430742 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0428605 |
| HMGA1 | high mobility group AT-hook 1 | -0.0425553 |
| GNAS | GNAS complex locus | -0.0425049 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0422335 |
| RPL35A | ribosomal protein L35a | -0.0412723 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0407723 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0407056 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0393127 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0392395 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0383513 |
| COPA | coatomer protein complex, subunit alpha | -0.0382402 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0381828 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0381182 |
| GOLGA4 | golgin A4 | -0.0378308 |
| RAI14 | retinoic acid induced 14 | -0.0377629 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0369734 |
| CADM1 | cell adhesion molecule 1 | -0.0363096 |
| MT2A | metallothionein 2A | -0.0362047 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0359448 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0359343 |
| FAM20C | family with sequence similarity 20, member C | -0.035749 |
| HLA-A | major histocompatibility complex, class I, A | -0.0354968 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0350673 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0345826 |
| RPS21 | ribosomal protein S21 | -0.033282 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0331893 |
| RBM39 | RNA binding motif protein 39 | -0.0330969 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0327822 |
| CALU | calumenin | -0.0324426 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0322247 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0320695 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0320123 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0318655 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0318423 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0314096 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.031338 |
| AEBP2 | AE binding protein 2 | -0.030306 |
| SETD5 | SET domain containing 5 | -0.0294415 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0291348 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0289304 |
| UBXN4 | UBX domain protein 4 | -0.0288879 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0288743 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0288082 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0287742 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.02877 |
| RPL26 | ribosomal protein L26 | -0.0285077 |
| TPI1 | triosephosphate isomerase 1 | -0.0282965 |
| CTSD | cathepsin D | -0.0282122 |
| HDLBP | high density lipoprotein binding protein | -0.0281612 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0277958 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0277237 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0274169 |
| RTN4 | reticulon 4 | -0.0273136 |
| RPL31 | ribosomal protein L31 | -0.0273084 |
| SYT1 | synaptotagmin I | -0.0270632 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0269025 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0265721 |
| RPS24 | ribosomal protein S24 | -0.0265488 |
| RPS6 | ribosomal protein S6 | -0.0264671 |
| ETNK1 | ethanolamine kinase 1 | -0.0264215 |
| EGR1 | early growth response 1 | -0.0261772 |
