| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.274468 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.115413 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.11446 |
| DSPP | dentin sialophosphoprotein | 0.0935154 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0802762 |
| MKI67 | marker of proliferation Ki-67 | 0.0780225 |
| ENO1 | enolase 1, (alpha) | 0.0762842 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0649903 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0647195 |
| CENPF | centromere protein F, 350/400kDa | 0.0618403 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.059653 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0586489 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.057201 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0551673 |
| SET | SET nuclear proto-oncogene | 0.0526897 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0523109 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0510264 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0499278 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0483989 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0481093 |
| WWOX | WW domain containing oxidoreductase | 0.0468855 |
| EZR | ezrin | 0.0449532 |
| SYT1 | synaptotagmin I | 0.0434715 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.043453 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0410251 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0392393 |
| FLNA | filamin A, alpha | 0.0389494 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0385327 |
| FAT1 | FAT atypical cadherin 1 | 0.0368388 |
| PCM1 | pericentriolar material 1 | 0.0362601 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0361873 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0361348 |
| RPL3 | ribosomal protein L3 | 0.0346092 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0341765 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.033038 |
| ACTN1 | actinin, alpha 1 | 0.0323361 |
| RPS12 | ribosomal protein S12 | 0.0320575 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0314757 |
| H1-4 | H1.4 linker histone, cluster member | 0.0304684 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0298599 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0293627 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.029215 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0287836 |
| MSN | moesin | 0.0282459 |
| PCDH9 | protocadherin 9 | 0.0281058 |
| TXNIP | thioredoxin interacting protein | 0.0278189 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0273359 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0273247 |
| PRELID2 | PRELI domain containing 2 | 0.0272538 |
| DST | dystonin | 0.0271945 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0271298 |
| VIM | vimentin | 0.0269878 |
| RAD51B | RAD51 paralog B | 0.0267686 |
| TNS3 | tensin 3 | 0.0267212 |
| CD44 | CD44 molecule (Indian blood group) | 0.0264922 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0264694 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0263826 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0262227 |
| CBFB | core-binding factor, beta subunit | 0.0261585 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.025754 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0256994 |
| TPM3 | tropomyosin 3 | 0.0256866 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0256342 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0255453 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0255296 |
| CEP112 | centrosomal protein 112kDa | 0.0253034 |
| RPS3A | ribosomal protein S3A | 0.0243882 |
| UBC | ubiquitin C | 0.0241769 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.024176 |
| EHBP1 | EH domain binding protein 1 | 0.0241495 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0241293 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0236765 |
| AXIN2 | axin 2 | 0.0234494 |
| H1-2 | H1.2 linker histone, cluster member | 0.0233147 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0232912 |
| AATF | apoptosis antagonizing transcription factor | 0.0231726 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0229806 |
| CTSB | cathepsin B | 0.0229692 |
| CCNL1 | cyclin L1 | 0.0229019 |
| ITGA6 | integrin, alpha 6 | 0.0228886 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0228025 |
| FHIT | fragile histidine triad | 0.0226169 |
| H1-5 | H1.5 linker histone, cluster member | 0.0224604 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0224053 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0217532 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0216757 |
| YAP1 | Yes-associated protein 1 | 0.0215895 |
| EXOC4 | exocyst complex component 4 | 0.0214432 |
| DIAPH2 | diaphanous-related formin 2 | 0.0210479 |
| HDGF | hepatoma-derived growth factor | 0.0206383 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0206089 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0205611 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.020335 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0203019 |
| FN1 | fibronectin 1 | 0.0202444 |
| EGFR | epidermal growth factor receptor | 0.0201961 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0200998 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0199349 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0198851 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0198221 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL35A | ribosomal protein L35a | -0.1234 |
| RPLP1 | ribosomal protein, large, P1 | -0.0804973 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0764273 |
| MORF4L2 | mortality factor 4 like 2 | -0.0760658 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0700901 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0657529 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0646992 |
| PERP | PERP, TP53 apoptosis effector | -0.0628998 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0628555 |
| RPS24 | ribosomal protein S24 | -0.0612185 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0608538 |
| AHNAK | AHNAK nucleoprotein | -0.0603998 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0583288 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0582894 |
| HMGA1 | high mobility group AT-hook 1 | -0.0576535 |
| ANXA2 | annexin A2 | -0.0567448 |
| ETNK1 | ethanolamine kinase 1 | -0.0566784 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0559665 |
| MED13 | mediator complex subunit 13 | -0.0553656 |
| TMSB10 | thymosin beta 10 | -0.0546731 |
| GLG1 | golgi glycoprotein 1 | -0.054222 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0532721 |
| LDHA | lactate dehydrogenase A | -0.052974 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0525583 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0524552 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0511509 |
| GOLGA4 | golgin A4 | -0.0505983 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0502839 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0468736 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0459507 |
| USP34 | ubiquitin specific peptidase 34 | -0.0457143 |
| RPS19 | ribosomal protein S19 | -0.0441975 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0438382 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0426933 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0418661 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0417149 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0416828 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.04104 |
| RPL27A | ribosomal protein L27a | -0.0407055 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0406608 |
| RTN3 | reticulon 3 | -0.0400495 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0395274 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0389587 |
| HM13 | histocompatibility (minor) 13 | -0.0389367 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0387533 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0385958 |
| NF1 | neurofibromin 1 | -0.0385678 |
| HDAC4 | histone deacetylase 4 | -0.0385461 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0383508 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0380992 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0375504 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0370004 |
| RBM39 | RNA binding motif protein 39 | -0.0369655 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0369564 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.036743 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0367272 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0364971 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0361585 |
| RPL34 | ribosomal protein L34 | -0.0359109 |
| CANX | calnexin | -0.0356335 |
| COG5 | component of oligomeric golgi complex 5 | -0.0354082 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0351287 |
| RPS13 | ribosomal protein S13 | -0.0345631 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0344222 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0341388 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0339947 |
| SDC4 | syndecan 4 | -0.0339915 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0337273 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0332519 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0332132 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0320245 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0319648 |
| KRT8 | keratin 8, type II | -0.0319355 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0319073 |
| GNAS | GNAS complex locus | -0.0319055 |
| FNIP1 | folliculin interacting protein 1 | -0.0318974 |
| HDLBP | high density lipoprotein binding protein | -0.0318597 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.031858 |
| TMEM41B | transmembrane protein 41B | -0.0318011 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0317598 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0316528 |
| RPL39 | ribosomal protein L39 | -0.0315945 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0314442 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0311186 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0309084 |
| RPL26 | ribosomal protein L26 | -0.0308876 |
| COPA | coatomer protein complex, subunit alpha | -0.0308445 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.03076 |
| SETD5 | SET domain containing 5 | -0.030475 |
| NKTR | natural killer cell triggering receptor | -0.0302963 |
| RPS20 | ribosomal protein S20 | -0.0302821 |
| CCND1 | cyclin D1 | -0.0302179 |
| AOPEP | aminopeptidase O (putative) | -0.0300385 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0300372 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0299973 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0299372 |
| NDRG1 | N-myc downstream regulated 1 | -0.0296737 |
| TMEM123 | transmembrane protein 123 | -0.0294164 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0291854 |
| JMJD1C | jumonji domain containing 1C | -0.0290459 |
