| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pyridoxine (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.151363 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.132296 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.112356 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.103211 |
| FN1 | fibronectin 1 | 0.0848266 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0822274 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0785921 |
| ASPH | aspartate beta-hydroxylase | 0.0692295 |
| MYO10 | myosin X | 0.0676819 |
| VCL | vinculin | 0.0644425 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0608108 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0606363 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0580909 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0564646 |
| LOX | lysyl oxidase | 0.0489015 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.047195 |
| FLNA | filamin A, alpha | 0.0426609 |
| GLIS3 | GLIS family zinc finger 3 | 0.0425641 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0413619 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0401218 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0389347 |
| EMP1 | epithelial membrane protein 1 | 0.0382263 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.037682 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0370053 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0361921 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.035503 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0353205 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0337049 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0336914 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0332524 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0314171 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0301684 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0301659 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0275258 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0266828 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.026488 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0256645 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0255225 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0253244 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0247511 |
| ITGA11 | integrin, alpha 11 | 0.024637 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0246215 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0244411 |
| HMGA2 | high mobility group AT-hook 2 | 0.0244168 |
| UBC | ubiquitin C | 0.0240269 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.023789 |
| EGR1 | early growth response 1 | 0.0231489 |
| MSN | moesin | 0.0230365 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0226046 |
| MAP1B | microtubule-associated protein 1B | 0.0224507 |
| TOP1 | topoisomerase (DNA) I | 0.0223956 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0218311 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0209016 |
| HBEGF | heparin-binding EGF-like growth factor | 0.020846 |
| DSPP | dentin sialophosphoprotein | 0.0202705 |
| BRD2 | bromodomain containing 2 | 0.0201921 |
| TLN1 | talin 1 | 0.0193562 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0193425 |
| TPM3 | tropomyosin 3 | 0.0191543 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0186089 |
| INTS6 | integrator complex subunit 6 | 0.017951 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0178104 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0174414 |
| RPS12 | ribosomal protein S12 | 0.0171508 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0171355 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0170882 |
| ANO6 | anoctamin 6 | 0.0168343 |
| SET | SET nuclear proto-oncogene | 0.0166646 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0165013 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0164461 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0161849 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0160142 |
| AMOTL1 | angiomotin like 1 | 0.0159423 |
| STC1 | stanniocalcin 1 | 0.0158836 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0156705 |
| RNF152 | ring finger protein 152 | 0.0155563 |
| IGF2 | insulin-like growth factor 2 | 0.0154332 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0152592 |
| RAB31 | RAB31, member RAS oncogene family | 0.0151953 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.015184 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.015183 |
| CAPRIN2 | caprin family member 2 | 0.0151275 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0150939 |
| MTAP | methylthioadenosine phosphorylase | 0.0149963 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0147716 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0147317 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0146532 |
| TXNIP | thioredoxin interacting protein | 0.0145489 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0145272 |
| EGFR | epidermal growth factor receptor | 0.0144561 |
| TUT7 | terminal uridylyl transferase 7 | 0.0144458 |
| FERMT2 | fermitin family member 2 | 0.0144453 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0143104 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0142785 |
| ERBIN | erbb2 interacting protein | 0.0141117 |
| HOMER1 | homer scaffolding protein 1 | 0.0141049 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.014073 |
| C1D | C1D nuclear receptor corepressor | 0.0139728 |
| NOTCH2 | notch 2 | 0.0138827 |
| CUL3 | cullin 3 | 0.0137972 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.25001 |
| VIM | vimentin | -0.181466 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.153096 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.143899 |
| MMP1 | matrix metallopeptidase 1 | -0.134941 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.13384 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.119731 |
| COL1A1 | collagen, type I, alpha 1 | -0.111994 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0951877 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0933307 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0931324 |
| NDRG1 | N-myc downstream regulated 1 | -0.089713 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0874565 |
| TMSB10 | thymosin beta 10 | -0.0855904 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0827784 |
| HLA-B | major histocompatibility complex, class I, B | -0.078793 |
| OXR1 | oxidation resistance 1 | -0.0768402 |
| TMEM165 | transmembrane protein 165 | -0.0748381 |
| CDH13 | cadherin 13 | -0.0725148 |
| MMP12 | matrix metallopeptidase 12 | -0.0724956 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0715339 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0709612 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.070757 |
| B2M | beta-2-microglobulin | -0.0672323 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0620755 |
| AHNAK | AHNAK nucleoprotein | -0.06148 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.06019 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0583514 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0579665 |
| GOLGA4 | golgin A4 | -0.0559891 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0548616 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0529944 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0519548 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0517235 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0511049 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0497449 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0491875 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0472504 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0466015 |
| RPLP1 | ribosomal protein, large, P1 | -0.0459209 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0446614 |
| RPL35A | ribosomal protein L35a | -0.0435257 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0427606 |
| FAM13A | family with sequence similarity 13, member A | -0.0417702 |
| FTL | ferritin, light polypeptide | -0.0415167 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.041475 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0412998 |
| LDHA | lactate dehydrogenase A | -0.0406669 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0395319 |
| COL5A2 | collagen, type V, alpha 2 | -0.0392124 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0388001 |
| NCKAP5 | NCK-associated protein 5 | -0.0383934 |
| ATP13A3 | ATPase type 13A3 | -0.0383562 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0381146 |
| NBEAL1 | neurobeachin-like 1 | -0.0375436 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0375101 |
| PRRX1 | paired related homeobox 1 | -0.037039 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0369398 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0368931 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0361204 |
| S100A6 | S100 calcium binding protein A6 | -0.0359527 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0358269 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0355195 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0350633 |
| TPM4 | tropomyosin 4 | -0.0350378 |
| MEIS1 | Meis homeobox 1 | -0.0350269 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0348214 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0347161 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0340284 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0331859 |
| HDLBP | high density lipoprotein binding protein | -0.0330164 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0324316 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0322378 |
| RPL34 | ribosomal protein L34 | -0.031984 |
| NREP | neuronal regeneration related protein | -0.0317816 |
| NPTX1 | neuronal pentraxin I | -0.0315523 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0312274 |
| FOXP1 | forkhead box P1 | -0.0311063 |
| KIAA1549L | KIAA1549-like | -0.0308749 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0304608 |
| HELZ | helicase with zinc finger | -0.0304124 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0303112 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0301327 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0299887 |
| COL5A1 | collagen, type V, alpha 1 | -0.0299153 |
| NAV2 | neuron navigator 2 | -0.0296244 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0295544 |
| RND3 | Rho family GTPase 3 | -0.0294056 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0291101 |
| CDC27 | cell division cycle 27 | -0.0290534 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0289354 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0278788 |
| PGK1 | phosphoglycerate kinase 1 | -0.027871 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0278549 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0274848 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0270964 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0270688 |
| SEC24D | SEC24 family member D | -0.0268747 |
| NGLY1 | N-glycanase 1 | -0.0268376 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0264799 |
