| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pyridoxine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.186024 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.165467 |
| CDH13 | cadherin 13 | 0.157039 |
| VIM | vimentin | 0.136696 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.133194 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.108867 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.105952 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0988701 |
| COL5A1 | collagen, type V, alpha 1 | 0.0845696 |
| EGFR | epidermal growth factor receptor | 0.0815579 |
| AHNAK | AHNAK nucleoprotein | 0.0809118 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0791951 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0756657 |
| POTEF | POTE ankyrin domain family, member F | 0.0724611 |
| FN1 | fibronectin 1 | 0.0715979 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0696079 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0668045 |
| TPM4 | tropomyosin 4 | 0.0646164 |
| PODXL | podocalyxin-like | 0.0641226 |
| MAP1B | microtubule-associated protein 1B | 0.063507 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0633387 |
| HDAC9 | histone deacetylase 9 | 0.0580046 |
| ASPH | aspartate beta-hydroxylase | 0.0573064 |
| CALR | calreticulin | 0.0555812 |
| CANX | calnexin | 0.0544767 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0538903 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0527719 |
| EFNA5 | ephrin-A5 | 0.0516465 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0504058 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0498201 |
| CENPF | centromere protein F, 350/400kDa | 0.0491518 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0482999 |
| CSTB | cystatin B (stefin B) | 0.047836 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.046676 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0457261 |
| TPM3 | tropomyosin 3 | 0.0454484 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0424647 |
| DCLK2 | doublecortin-like kinase 2 | 0.0423299 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0423248 |
| PKM | pyruvate kinase, muscle | 0.0410979 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.040838 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0406842 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0405907 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0396153 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0395524 |
| MSN | moesin | 0.0394647 |
| RND3 | Rho family GTPase 3 | 0.03811 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0367976 |
| DSPP | dentin sialophosphoprotein | 0.0359562 |
| ENO1 | enolase 1, (alpha) | 0.0353911 |
| CYTH3 | cytohesin 3 | 0.0344223 |
| DST | dystonin | 0.0338923 |
| S100A10 | S100 calcium binding protein A10 | 0.0337446 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0328039 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0320528 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0318548 |
| NDRG1 | N-myc downstream regulated 1 | 0.0315665 |
| SEPTIN7 | septin 7 | 0.0315631 |
| TAGLN2 | transgelin 2 | 0.0315333 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0305255 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0304288 |
| COPA | coatomer protein complex, subunit alpha | 0.02984 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0283019 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0280693 |
| MSI2 | musashi RNA-binding protein 2 | 0.027754 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.027743 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0272964 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.02716 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0270312 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0266982 |
| CUX1 | cut-like homeobox 1 | 0.0262923 |
| FMN2 | formin 2 | 0.0262398 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0262187 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0261511 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.025851 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0252498 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.024833 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0246958 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0245982 |
| PFN1 | profilin 1 | 0.0244368 |
| MCL1 | myeloid cell leukemia 1 | 0.0243992 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.023731 |
| GOLGB1 | golgin B1 | 0.023686 |
| PLXNA2 | plexin A2 | 0.0235977 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0235365 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0234953 |
| FSTL1 | follistatin-like 1 | 0.0234737 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0233748 |
| ANXA1 | annexin A1 | 0.0232709 |
| E2F7 | E2F transcription factor 7 | 0.0232078 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0231235 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.022822 |
| NAV1 | neuron navigator 1 | 0.0227755 |
| RASAL2 | RAS protein activator like 2 | 0.0226703 |
| LMNA | lamin A/C | 0.0226343 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0223766 |
| FAM107B | family with sequence similarity 107, member B | 0.0223755 |
| LRRC17 | leucine rich repeat containing 17 | 0.022352 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0222574 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0222093 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FBN1 | fibrillin 1 | -0.145211 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.130676 |
| COL1A2 | collagen, type I, alpha 2 | -0.0915346 |
| COL3A1 | collagen, type III, alpha 1 | -0.0662344 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.064411 |
| MT2A | metallothionein 2A | -0.0599679 |
| TMSB10 | thymosin beta 10 | -0.0569645 |
| THBS2 | thrombospondin 2 | -0.0568598 |
| LOXL2 | lysyl oxidase-like 2 | -0.055247 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0540658 |
| GPC6 | glypican 6 | -0.0508151 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0444626 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0440091 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0437514 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.043377 |
| CD44 | CD44 molecule (Indian blood group) | -0.043043 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0415808 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0405515 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0380304 |
| HLA-B | major histocompatibility complex, class I, B | -0.0361522 |
| COL5A2 | collagen, type V, alpha 2 | -0.0348154 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0342932 |
| SBF2 | SET binding factor 2 | -0.0334177 |
| ATP13A3 | ATPase type 13A3 | -0.0330236 |
| STC1 | stanniocalcin 1 | -0.0322774 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0318568 |
| FRMD5 | FERM domain containing 5 | -0.0318102 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0301417 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0294748 |
| TMOD1 | tropomodulin 1 | -0.0292606 |
| OGA | O-GlcNAcase | -0.0284674 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0279914 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0274981 |
| HLA-E | major histocompatibility complex, class I, E | -0.0271118 |
| LRRC49 | leucine rich repeat containing 49 | -0.0269735 |
| UBC | ubiquitin C | -0.0262185 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0262018 |
| AUTS2 | autism susceptibility candidate 2 | -0.0257883 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0256904 |
| WTAP | Wilms tumor 1 associated protein | -0.0252865 |
| GLIS3 | GLIS family zinc finger 3 | -0.0246766 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0242647 |
| KIFAP3 | kinesin-associated protein 3 | -0.0240395 |
| TDRD7 | tudor domain containing 7 | -0.0237463 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0232345 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0231223 |
| TRIM22 | tripartite motif containing 22 | -0.0227497 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0218426 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0217761 |
| PXDN | peroxidasin | -0.0217352 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0215085 |
| HLA-C | major histocompatibility complex, class I, C | -0.0215079 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0213577 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0212316 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0211236 |
| MEIS2 | Meis homeobox 2 | -0.0209923 |
| CTSB | cathepsin B | -0.0209334 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0206355 |
| RNF145 | ring finger protein 145 | -0.0201473 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0200209 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0195362 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0193934 |
| OPTN | optineurin | -0.019356 |
| SDC4 | syndecan 4 | -0.0192372 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.019168 |
| MTSS1 | metastasis suppressor 1 | -0.0191446 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0189742 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0188578 |
| APP | amyloid beta (A4) precursor protein | -0.0184898 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0184852 |
| GASK1B | golgi associated kinase 1B | -0.0183732 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0182424 |
| ABI2 | abl-interactor 2 | -0.0181841 |
| LOX | lysyl oxidase | -0.0180521 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0179635 |
| NPR2 | natriuretic peptide receptor 2 | -0.0178169 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0177267 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0174459 |
| SVIL | supervillin | -0.0174448 |
| TRIM56 | tripartite motif containing 56 | -0.0172886 |
| KIAA1217 | KIAA1217 | -0.0172401 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0172364 |
| ADAR | adenosine deaminase, RNA-specific | -0.0171501 |
| CLU | clusterin | -0.0168839 |
| PRKD3 | protein kinase D3 | -0.0167839 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0166025 |
| ANK2 | ankyrin 2, neuronal | -0.0163815 |
| NF1 | neurofibromin 1 | -0.016287 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0162467 |
| CAVIN1 | caveolae associated protein 1 | -0.0160366 |
| MAP4 | microtubule-associated protein 4 | -0.0159879 |
| PRRX1 | paired related homeobox 1 | -0.0156902 |
| RHOQ | ras homolog family member Q | -0.0154861 |
| EHBP1 | EH domain binding protein 1 | -0.0153754 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0153671 |
| MX2 | MX dynamin-like GTPase 2 | -0.0151766 |
| SRPX | sushi-repeat containing protein, X-linked | -0.0151522 |
| CLSTN2 | calsyntenin 2 | -0.0149826 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0149485 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0146887 |
