| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VMP1 | vacuole membrane protein 1 | 0.111536 |
| EXT1 | exostosin glycosyltransferase 1 | 0.111431 |
| PLAT | plasminogen activator, tissue | 0.107218 |
| VCL | vinculin | 0.101576 |
| NRG1 | neuregulin 1 | 0.0989193 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0931339 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0891964 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0891269 |
| LSAMP | limbic system-associated membrane protein | 0.0856372 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0760214 |
| BPTF | bromodomain PHD finger transcription factor | 0.0755206 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0685012 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0679921 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0677798 |
| PRKCA | protein kinase C, alpha | 0.0673344 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0666442 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0660117 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0622052 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0602253 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0599129 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0595679 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0593994 |
| B2M | beta-2-microglobulin | 0.0593669 |
| CADM1 | cell adhesion molecule 1 | 0.0561371 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0530074 |
| TPM1 | tropomyosin 1 (alpha) | 0.0516078 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0503291 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0479223 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0475799 |
| CALD1 | caldesmon 1 | 0.0474003 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0467666 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0464589 |
| MEF2A | myocyte enhancer factor 2A | 0.0462712 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0451054 |
| DST | dystonin | 0.0441751 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0425214 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0419327 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0418423 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0414939 |
| ASPH | aspartate beta-hydroxylase | 0.0410731 |
| FAM13A | family with sequence similarity 13, member A | 0.0409862 |
| IER3 | immediate early response 3 | 0.0407413 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.04053 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.040396 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0400695 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0399928 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0395905 |
| EFNA5 | ephrin-A5 | 0.039175 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0386706 |
| EGR1 | early growth response 1 | 0.0378434 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0376762 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0375456 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0374299 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0358906 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0356394 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0348998 |
| DTNA | dystrobrevin, alpha | 0.0347626 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0347492 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0347123 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0345133 |
| EGFR | epidermal growth factor receptor | 0.0340732 |
| NREP | neuronal regeneration related protein | 0.0336175 |
| VIM | vimentin | 0.0335552 |
| MCL1 | myeloid cell leukemia 1 | 0.0329906 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0329459 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.0328901 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0323018 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0321273 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0320338 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0317263 |
| STK38L | serine/threonine kinase 38 like | 0.0311895 |
| MBTD1 | mbt domain containing 1 | 0.0311363 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0311175 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0311132 |
| TPM4 | tropomyosin 4 | 0.0310441 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0309344 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0309172 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0308275 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0307488 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0307211 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | 0.0304446 |
| KLHL13 | kelch-like family member 13 | 0.0303725 |
| RPL23 | ribosomal protein L23 | 0.0302366 |
| TPM3 | tropomyosin 3 | 0.0297341 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0296815 |
| RNF150 | ring finger protein 150 | 0.0296327 |
| RAD51B | RAD51 paralog B | 0.0286501 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0284656 |
| TLE4 | transducin-like enhancer of split 4 | 0.0284276 |
| LIMA1 | LIM domain and actin binding 1 | 0.0278827 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0273558 |
| CRH | corticotropin releasing hormone | 0.0270569 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0268776 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0267812 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0267039 |
| USP34 | ubiquitin specific peptidase 34 | 0.0266958 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0266674 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0262027 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0258967 |
| TRIM24 | tripartite motif containing 24 | 0.025821 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.184153 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0847118 |
| PTMA | prothymosin, alpha | -0.060744 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0607159 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0559182 |
| COL1A1 | collagen, type I, alpha 1 | -0.055191 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0487069 |
| FMN1 | formin 1 | -0.0450609 |
| LPIN1 | lipin 1 | -0.0441939 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0407548 |
| TRIB2 | tribbles pseudokinase 2 | -0.0384101 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0355096 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0354423 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0331072 |
| PHF3 | PHD finger protein 3 | -0.0328927 |
| USP3 | ubiquitin specific peptidase 3 | -0.032274 |
| LMNA | lamin A/C | -0.0311526 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0310776 |
| RPL12 | ribosomal protein L12 | -0.0310178 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0300286 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0293167 |
| RNF213 | ring finger protein 213 | -0.0288427 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0287837 |
| WDR45B | WD repeat domain 45B | -0.0278008 |
| TULP4 | tubby like protein 4 | -0.0274424 |
| RPS24 | ribosomal protein S24 | -0.0273753 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0272155 |
| AOPEP | aminopeptidase O (putative) | -0.0259543 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0249055 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0247195 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0246163 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -0.0243085 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0236393 |
| MAP1B | microtubule-associated protein 1B | -0.023582 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0235481 |
| SERINC1 | serine incorporator 1 | -0.0234888 |
| ATOSA | atos homolog A | -0.0231235 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0226118 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0223702 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.022317 |
| SYT1 | synaptotagmin I | -0.0223087 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0222761 |
| OGA | O-GlcNAcase | -0.0220788 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0220469 |
| ADAR | adenosine deaminase, RNA-specific | -0.0219324 |
| UBAC2 | UBA domain containing 2 | -0.0216676 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0216215 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0214526 |
| ARF1 | ADP-ribosylation factor 1 | -0.0212427 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0212425 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0210739 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0207915 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0207476 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | -0.0205286 |
| HMGB2 | high mobility group box 2 | -0.0202878 |
| RPL37A | ribosomal protein L37a | -0.0202784 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0200872 |
| SEPTIN2 | septin 2 | -0.0199452 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0198095 |
| SYNJ2BP | synaptojanin 2 binding protein | -0.0196638 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0196386 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0195598 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0194996 |
| NUP160 | nucleoporin 160kDa | -0.0193112 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0192873 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0192304 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0191167 |
| KIF21A | kinesin family member 21A | -0.0191062 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0190498 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0186132 |
| DSCAM | Down syndrome cell adhesion molecule | -0.018458 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0184257 |
| PHOX2B | paired-like homeobox 2b | -0.0182732 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0182486 |
| DENND1A | DENN/MADD domain containing 1A | -0.0182372 |
| NRP1 | neuropilin 1 | -0.0181244 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0180785 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | -0.018072 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0180318 |
| MEIS2 | Meis homeobox 2 | -0.0179322 |
| TMSB10 | thymosin beta 10 | -0.0176725 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0174556 |
| COL3A1 | collagen, type III, alpha 1 | -0.0173483 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.017298 |
| WTAP | Wilms tumor 1 associated protein | -0.0172679 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.01719 |
| STX18 | syntaxin 18 | -0.0171787 |
| MATR3 | matrin 3 | -0.0170035 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0166115 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0165997 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0163209 |
| CERT1 | ceramide transporter 1 | -0.0163145 |
| ZNF37A | zinc finger protein 37A | -0.0162367 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0161668 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 | -0.0160318 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0160008 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.0159979 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | -0.0159858 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.0159825 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0159623 |
