| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pyridoxine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.157091 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0945214 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0910531 |
| VCL | vinculin | 0.0907705 |
| AREG | amphiregulin | 0.0868094 |
| GPHN | gephyrin | 0.0846829 |
| RPS12 | ribosomal protein S12 | 0.0783971 |
| RPS2 | ribosomal protein S2 | 0.0731412 |
| MYO1E | myosin IE | 0.0712554 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0683417 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0682552 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0657067 |
| RPL26 | ribosomal protein L26 | 0.0560317 |
| B2M | beta-2-microglobulin | 0.0544071 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0533782 |
| RPS8 | ribosomal protein S8 | 0.051136 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0510298 |
| RPL35A | ribosomal protein L35a | 0.0487107 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.047802 |
| EREG | epiregulin | 0.0471682 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0433967 |
| PIGR | polymeric immunoglobulin receptor | 0.0428572 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0415893 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0414802 |
| ABHD2 | abhydrolase domain containing 2 | 0.0407351 |
| GOLGA4 | golgin A4 | 0.0405827 |
| RPS27A | ribosomal protein S27a | 0.0401707 |
| COG5 | component of oligomeric golgi complex 5 | 0.0390376 |
| RPS3 | ribosomal protein S3 | 0.036735 |
| GDF15 | growth differentiation factor 15 | 0.0367148 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0355283 |
| NEBL | nebulette | 0.034701 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0338218 |
| LIPH | lipase, member H | 0.033807 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0336876 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.033459 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0323434 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0321617 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.032127 |
| TRIM2 | tripartite motif containing 2 | 0.0314662 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0311494 |
| WDR43 | WD repeat domain 43 | 0.0301406 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0300999 |
| EPCAM | epithelial cell adhesion molecule | 0.0297487 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0296291 |
| PKP2 | plakophilin 2 | 0.0295156 |
| RPS21 | ribosomal protein S21 | 0.0294027 |
| KLF6 | Kruppel-like factor 6 | 0.0293092 |
| NFIA | nuclear factor I/A | 0.029262 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.029184 |
| VMP1 | vacuole membrane protein 1 | 0.0290861 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0289331 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0281714 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0280495 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.027916 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0275882 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0275754 |
| TPM3 | tropomyosin 3 | 0.0275579 |
| PNN | pinin, desmosome associated protein | 0.02734 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0268834 |
| FOXP2 | forkhead box P2 | 0.026847 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0266817 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.026545 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0262473 |
| PMM2 | phosphomannomutase 2 | 0.0260245 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0259106 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.025892 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0257895 |
| RPL18 | ribosomal protein L18 | 0.0257323 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0257181 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0256818 |
| USP6NL | USP6 N-terminal like | 0.0254076 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0253609 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0253245 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.025228 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0251815 |
| SMAD2 | SMAD family member 2 | 0.0246523 |
| TFRC | transferrin receptor | 0.0246321 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0245481 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0242643 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0241603 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0241566 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0241506 |
| IGFL2 | IGF-like family member 2 | 0.0240777 |
| COMMD10 | COMM domain containing 10 | 0.024018 |
| CTBP2 | C-terminal binding protein 2 | 0.023535 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0233383 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0231189 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.022775 |
| RANBP2 | RAN binding protein 2 | 0.0227126 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.022647 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0226131 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0224351 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0223377 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0223085 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0219357 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0215946 |
| FNBP4 | formin binding protein 4 | 0.0215503 |
| POF1B | premature ovarian failure, 1B | 0.0213902 |
| MECOM | MDS1 and EVI1 complex locus | 0.021341 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.203546 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.191901 |
| NDRG1 | N-myc downstream regulated 1 | -0.094498 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0920006 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0831145 |
| EZR | ezrin | -0.0815208 |
| TMSB10 | thymosin beta 10 | -0.0779064 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0643999 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0594787 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.058579 |
| FLNB | filamin B, beta | -0.0529606 |
| S100A6 | S100 calcium binding protein A6 | -0.0527352 |
| RPS6 | ribosomal protein S6 | -0.0524956 |
| ITGA6 | integrin, alpha 6 | -0.0514486 |
| NPSR1 | neuropeptide S receptor 1 | -0.0509548 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0506808 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.050202 |
| FAM13A | family with sequence similarity 13, member A | -0.0486264 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0458669 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0448886 |
| PKM | pyruvate kinase, muscle | -0.0443494 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0438137 |
| RPLP1 | ribosomal protein, large, P1 | -0.0436914 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0422091 |
| LOC112694756 | uncharaterized LOC112694756 | -0.041408 |
| KRT18 | keratin 18, type I | -0.0405127 |
| PRELID2 | PRELI domain containing 2 | -0.0392641 |
| MT2A | metallothionein 2A | -0.0380437 |
| ANXA1 | annexin A1 | -0.0378888 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0370691 |
| KRT19 | keratin 19, type I | -0.0362136 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.03604 |
| LMNA | lamin A/C | -0.0354845 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0343486 |
| RPL37 | ribosomal protein L37 | -0.0328889 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0328706 |
| ITGB4 | integrin, beta 4 | -0.0323686 |
| POTEF | POTE ankyrin domain family, member F | -0.0320454 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0319393 |
| CCNY | cyclin Y | -0.0313257 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0309814 |
| FOSL1 | FOS-like antigen 1 | -0.0304514 |
| VEGFA | vascular endothelial growth factor A | -0.0302725 |
| HMGA1 | high mobility group AT-hook 1 | -0.030105 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0298531 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.029472 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0293664 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0293599 |
| WDR45B | WD repeat domain 45B | -0.0291196 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0289747 |
| FTL | ferritin, light polypeptide | -0.0284737 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0279797 |
| RPS19 | ribosomal protein S19 | -0.0279482 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0273948 |
| LMO7 | LIM domain 7 | -0.0271694 |
| EMP1 | epithelial membrane protein 1 | -0.0269614 |
| HMGB1 | high mobility group box 1 | -0.0266864 |
| LDHA | lactate dehydrogenase A | -0.026376 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.02631 |
| FBXO11 | F-box protein 11 | -0.0262303 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0247366 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0246312 |
| AGR2 | anterior gradient 2 | -0.024396 |
| DIAPH3 | diaphanous-related formin 3 | -0.0241303 |
| EGFR | epidermal growth factor receptor | -0.0240268 |
| ANXA2 | annexin A2 | -0.023811 |
| DIAPH2 | diaphanous-related formin 2 | -0.023632 |
| ZNF292 | zinc finger protein 292 | -0.0234977 |
| CENPF | centromere protein F, 350/400kDa | -0.0232539 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0231432 |
| ATF4 | activating transcription factor 4 | -0.0230566 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.023049 |
| PARD3 | par-3 family cell polarity regulator | -0.0226263 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0225492 |
| YBX1 | Y box binding protein 1 | -0.0224838 |
| RPL13A | ribosomal protein L13a | -0.0224314 |
| FNBP1L | formin binding protein 1-like | -0.022424 |
| SVIL | supervillin | -0.0223785 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0221916 |
| DENND1A | DENN/MADD domain containing 1A | -0.0220527 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0219237 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0218351 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0216228 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0216097 |
| RAD51B | RAD51 paralog B | -0.0212946 |
| CA12 | carbonic anhydrase XII | -0.0212233 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0209743 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0208822 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0208521 |
| S100A14 | S100 calcium binding protein A14 | -0.0208315 |
| RPL27A | ribosomal protein L27a | -0.0208266 |
| DNM2 | dynamin 2 | -0.0207491 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.020568 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0205394 |
| STK39 | serine threonine kinase 39 | -0.0203914 |
| RPLP0 | ribosomal protein, large, P0 | -0.0203711 |
| RPL7A | ribosomal protein L7a | -0.0199765 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0193281 |
| SEPTIN7 | septin 7 | -0.0191325 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0190016 |
