| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.272725 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.160902 |
| LOX | lysyl oxidase | 0.121156 |
| NDRG1 | N-myc downstream regulated 1 | 0.100048 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0816859 |
| NAV2 | neuron navigator 2 | 0.0750564 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0691985 |
| PRELID2 | PRELI domain containing 2 | 0.0639927 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0632963 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0575456 |
| FN1 | fibronectin 1 | 0.0567355 |
| AHNAK | AHNAK nucleoprotein | 0.0561076 |
| FAM13A | family with sequence similarity 13, member A | 0.0551191 |
| ENO1 | enolase 1, (alpha) | 0.0548524 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0539919 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0525138 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0518719 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.051372 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0513086 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0472284 |
| CA12 | carbonic anhydrase XII | 0.0472137 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0445039 |
| SMAD3 | SMAD family member 3 | 0.0433256 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0430962 |
| LOXL2 | lysyl oxidase-like 2 | 0.04277 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0379916 |
| NGLY1 | N-glycanase 1 | 0.0361087 |
| LDHA | lactate dehydrogenase A | 0.0348676 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0345764 |
| FLNB | filamin B, beta | 0.0343976 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0335121 |
| ITGAV | integrin, alpha V | 0.0334098 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0331781 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0325277 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0318035 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0305313 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0301969 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0294624 |
| PLIN2 | perilipin 2 | 0.0294481 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0293805 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0292233 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.028874 |
| MEF2A | myocyte enhancer factor 2A | 0.0282584 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0277527 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0277044 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.027378 |
| MT2A | metallothionein 2A | 0.0271263 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0270273 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0267411 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0265802 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.026432 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0263847 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0263083 |
| SFTPA2 | surfactant protein A2 | 0.0255283 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0250298 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0249867 |
| DST | dystonin | 0.0247144 |
| ANXA1 | annexin A1 | 0.0245404 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.024152 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0240571 |
| KLF6 | Kruppel-like factor 6 | 0.0239195 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0238304 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0234564 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0234301 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0232424 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0231425 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0230691 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.022935 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0229143 |
| ANXA2 | annexin A2 | 0.0227324 |
| ZNF292 | zinc finger protein 292 | 0.0222904 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0222066 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0221798 |
| PFKP | phosphofructokinase, platelet | 0.0221239 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0214297 |
| CDCP1 | CUB domain containing protein 1 | 0.0213505 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0208252 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0207913 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0207582 |
| ANO6 | anoctamin 6 | 0.020727 |
| ARFGEF3 | ARFGEF family member 3 | 0.0205273 |
| CD109 | CD109 molecule | 0.0205154 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0204164 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.020268 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0202487 |
| HDAC9 | histone deacetylase 9 | 0.0201435 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0200896 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0200523 |
| ZNF638 | zinc finger protein 638 | 0.0196216 |
| RAI14 | retinoic acid induced 14 | 0.0196023 |
| MXI1 | MAX interactor 1, dimerization protein | 0.019036 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0187402 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0186655 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.018655 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0186438 |
| PGK1 | phosphoglycerate kinase 1 | 0.01856 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0184132 |
| TXNIP | thioredoxin interacting protein | 0.0182616 |
| RARB | retinoic acid receptor, beta | 0.0181647 |
| FAM20C | family with sequence similarity 20, member C | 0.0181271 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.132254 |
| NRG1 | neuregulin 1 | -0.111238 |
| GLCCI1 | glucocorticoid induced 1 | -0.0933271 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0874595 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0846141 |
| CDH13 | cadherin 13 | -0.072398 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0721758 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0694131 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0687922 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0621733 |
| NRP1 | neuropilin 1 | -0.0596007 |
| VRK2 | vaccinia related kinase 2 | -0.0595016 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0562867 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0555943 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0518912 |
| NUMB | numb homolog (Drosophila) | -0.0508424 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0490338 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0456404 |
| OSMR | oncostatin M receptor | -0.0455816 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0436343 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0435352 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0431798 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0428285 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0423006 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0422325 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0417277 |
| CLMP | CXADR-like membrane protein | -0.0412956 |
| ATG7 | autophagy related 7 | -0.0398567 |
| FRMD4A | FERM domain containing 4A | -0.0395125 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0387313 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0374482 |
| NAV3 | neuron navigator 3 | -0.0365085 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0364382 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0363522 |
| KYNU | kynureninase | -0.0360667 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0357286 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0349979 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.034018 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0334227 |
| GLIS3 | GLIS family zinc finger 3 | -0.0326877 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0325554 |
| PTMA | prothymosin, alpha | -0.0318544 |
| DNER | delta/notch-like EGF repeat containing | -0.0313702 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0311473 |
| MTSS1 | metastasis suppressor 1 | -0.0309099 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0305002 |
| S100A6 | S100 calcium binding protein A6 | -0.0303925 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0303729 |
| ETV6 | ets variant 6 | -0.0298309 |
| PRRX1 | paired related homeobox 1 | -0.0294642 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0291674 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0291589 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0289708 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0286338 |
| MECOM | MDS1 and EVI1 complex locus | -0.0285649 |
| TMEM165 | transmembrane protein 165 | -0.0283894 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.02804 |
| PARD3 | par-3 family cell polarity regulator | -0.0277679 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0277561 |
| PCNX1 | pecanex 1 | -0.0274106 |
| BMERB1 | bMERB domain containing 1 | -0.0273073 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0271697 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0266686 |
| ZNF804A | zinc finger protein 804A | -0.0262633 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0261988 |
| ZNF609 | zinc finger protein 609 | -0.0260488 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0259189 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0257975 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0253307 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0252864 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0251654 |
| SP100 | SP100 nuclear antigen | -0.0251205 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0250283 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0248661 |
| CUX1 | cut-like homeobox 1 | -0.0247106 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0246396 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0245027 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0239471 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0239191 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0235673 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0231771 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0231254 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0230689 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0229814 |
| HMGA2 | high mobility group AT-hook 2 | -0.0228637 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0228347 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0228326 |
| IL1B | interleukin 1, beta | -0.0227642 |
| IFI44 | interferon-induced protein 44 | -0.0226046 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0224388 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0222672 |
| ANXA10 | annexin A10 | -0.0220241 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0218361 |
| GPC6 | glypican 6 | -0.0217662 |
| PCNX4 | pecanex 4 | -0.0217277 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0216086 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0215844 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0214652 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.021033 |
| PRR16 | proline rich 16 | -0.0209279 |
