| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.237221 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.173723 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.147043 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.145048 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.109245 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.10484 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0977613 |
| AHNAK | AHNAK nucleoprotein | 0.0828557 |
| ASPH | aspartate beta-hydroxylase | 0.0669116 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0635434 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0625265 |
| FMNL2 | formin-like 2 | 0.0611202 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0578134 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0573329 |
| ACTG1 | actin gamma 1 | 0.0571577 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0560374 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0551722 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0517432 |
| VMP1 | vacuole membrane protein 1 | 0.0504146 |
| GLG1 | golgi glycoprotein 1 | 0.0501756 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0499006 |
| CMIP | c-Maf inducing protein | 0.0468128 |
| ENO1 | enolase 1, (alpha) | 0.0461013 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0449191 |
| SNX14 | sorting nexin 14 | 0.044736 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0438101 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0431384 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0427265 |
| RPL4 | ribosomal protein L4 | 0.0414051 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0412132 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.040726 |
| CAVIN1 | caveolae associated protein 1 | 0.0402764 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0398618 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0398378 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0397241 |
| IER3 | immediate early response 3 | 0.0389797 |
| FAM107B | family with sequence similarity 107, member B | 0.0388878 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.038457 |
| FLNB | filamin B, beta | 0.0379697 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0368732 |
| TPM3 | tropomyosin 3 | 0.0358802 |
| RPS8 | ribosomal protein S8 | 0.0356521 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0354669 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0353721 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0343062 |
| KLF6 | Kruppel-like factor 6 | 0.0341536 |
| RPL19 | ribosomal protein L19 | 0.0340074 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0336601 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0334119 |
| KIF5B | kinesin family member 5B | 0.0321588 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0320553 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0314701 |
| CFDP1 | craniofacial development protein 1 | 0.0310694 |
| PGK1 | phosphoglycerate kinase 1 | 0.0301537 |
| CYTH1 | cytohesin 1 | 0.0286513 |
| PDE8A | phosphodiesterase 8A | 0.0281288 |
| RPS3 | ribosomal protein S3 | 0.0279928 |
| RPS2 | ribosomal protein S2 | 0.0278863 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0275341 |
| ITGA6 | integrin, alpha 6 | 0.0273623 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0272209 |
| SRP54 | signal recognition particle 54kDa | 0.0270789 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.026905 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0268392 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.026661 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0265952 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0263947 |
| USP53 | ubiquitin specific peptidase 53 | 0.0261548 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0261166 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0260839 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0258172 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0256863 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0255363 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0254672 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0253686 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0252855 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.0250505 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0250325 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0247004 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0246634 |
| CLTC | clathrin, heavy chain (Hc) | 0.0246051 |
| ATP11A | ATPase, class VI, type 11A | 0.0244282 |
| APP | amyloid beta (A4) precursor protein | 0.0243405 |
| SPAG9 | sperm associated antigen 9 | 0.0242815 |
| NDRG1 | N-myc downstream regulated 1 | 0.0239634 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0238312 |
| RPS12 | ribosomal protein S12 | 0.0234808 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0233755 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0226226 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.022528 |
| ANXA2 | annexin A2 | 0.022468 |
| LAMC2 | laminin, gamma 2 | 0.0224156 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0223004 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.022263 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | 0.0222163 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0222134 |
| OGA | O-GlcNAcase | 0.0222005 |
| PRKCE | protein kinase C, epsilon | 0.0221277 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0219421 |
| RAI1 | retinoic acid induced 1 | 0.0218359 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.191378 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.134402 |
| IGF2 | insulin-like growth factor 2 | -0.13208 |
| TMSB10 | thymosin beta 10 | -0.112333 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.102259 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0999888 |
| VIM | vimentin | -0.0908538 |
| GRAMD1B | GRAM domain containing 1B | -0.066794 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0661392 |
| POTEF | POTE ankyrin domain family, member F | -0.0545401 |
| BICC1 | BicC family RNA binding protein 1 | -0.0504693 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0495945 |
| SVIL | supervillin | -0.0449303 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0435775 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0404333 |
| S100A6 | S100 calcium binding protein A6 | -0.0396899 |
| OSMR | oncostatin M receptor | -0.0380762 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0378961 |
| RAD51B | RAD51 paralog B | -0.0374653 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0369841 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0365881 |
| EGR1 | early growth response 1 | -0.0361511 |
| HDAC9 | histone deacetylase 9 | -0.0356171 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0352296 |
| DST | dystonin | -0.0344479 |
| NEGR1 | neuronal growth regulator 1 | -0.0338299 |
| NTN4 | netrin 4 | -0.0337671 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0334243 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0329338 |
| FGB | fibrinogen beta chain | -0.0325951 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0322455 |
| MAP1B | microtubule-associated protein 1B | -0.0307677 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0305633 |
| TPM1 | tropomyosin 1 (alpha) | -0.0305293 |
| LAMB1 | laminin, beta 1 | -0.0297996 |
| RNF213 | ring finger protein 213 | -0.0278862 |
| PCBP2 | poly(rC) binding protein 2 | -0.0272359 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0263714 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0261738 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0261487 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0260076 |
| EFNA5 | ephrin-A5 | -0.0258327 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0253016 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0252804 |
| NRG1 | neuregulin 1 | -0.0252193 |
| MYADM | myeloid-associated differentiation marker | -0.0251085 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0248736 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0239881 |
| RAB7A | RAB7A, member RAS oncogene family | -0.023791 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0232487 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0231735 |
| CUX1 | cut-like homeobox 1 | -0.0230965 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0220224 |
| PCED1B | PC-esterase domain containing 1B | -0.0219973 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0219577 |
| HMGA1 | high mobility group AT-hook 1 | -0.0219281 |
| GLIS3 | GLIS family zinc finger 3 | -0.0217977 |
| PFN1 | profilin 1 | -0.0217757 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0217289 |
| LAMA5 | laminin, alpha 5 | -0.0217068 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.021641 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.021607 |
| PDE10A | phosphodiesterase 10A | -0.0214171 |
| DENND4A | DENN/MADD domain containing 4A | -0.0213721 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0212361 |
| WWOX | WW domain containing oxidoreductase | -0.021175 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0210468 |
| MCL1 | myeloid cell leukemia 1 | -0.0209048 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0207512 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0205723 |
| WDR43 | WD repeat domain 43 | -0.0199769 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0197291 |
| EHBP1 | EH domain binding protein 1 | -0.019591 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0195139 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.0193601 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0191532 |
| TMEM131 | transmembrane protein 131 | -0.0190047 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0189326 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0189087 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0187715 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.0187105 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0186869 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0186707 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0184155 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0181603 |
| CCDC88A | coiled-coil domain containing 88A | -0.0180338 |
| CCNL1 | cyclin L1 | -0.018024 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0180114 |
| FTL | ferritin, light polypeptide | -0.0179407 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0179129 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0176471 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.017647 |
| FOXP1 | forkhead box P1 | -0.0176378 |
| ZNF609 | zinc finger protein 609 | -0.0174629 |
| ZFHX3 | zinc finger homeobox 3 | -0.0172529 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0170778 |
| EXOC4 | exocyst complex component 4 | -0.0170603 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.016986 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0168447 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0166894 |
