| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.212201 |
| TXNRD1 | thioredoxin reductase 1 | 0.140217 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0888719 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0843268 |
| AHNAK | AHNAK nucleoprotein | 0.08051 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0788056 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.070175 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0680145 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0612146 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0607135 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0597083 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0588902 |
| TPI1 | triosephosphate isomerase 1 | 0.0587858 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0568994 |
| PGK1 | phosphoglycerate kinase 1 | 0.0567865 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0477241 |
| ACTG1 | actin gamma 1 | 0.0464171 |
| ENO1 | enolase 1, (alpha) | 0.0452105 |
| YBX3 | Y box binding protein 3 | 0.0451779 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0401715 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.039634 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0396267 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0387025 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.037881 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0374559 |
| DST | dystonin | 0.0371725 |
| XPO1 | exportin 1 | 0.035855 |
| RPS3 | ribosomal protein S3 | 0.0355416 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0355332 |
| CLTC | clathrin, heavy chain (Hc) | 0.0348592 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0348243 |
| CAPRIN2 | caprin family member 2 | 0.0346531 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0343261 |
| OGA | O-GlcNAcase | 0.0335641 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0329389 |
| CCND2 | cyclin D2 | 0.0326857 |
| HELZ | helicase with zinc finger | 0.0308087 |
| STC1 | stanniocalcin 1 | 0.0301636 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0301133 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0298311 |
| KRT18 | keratin 18, type I | 0.0295406 |
| TPM3 | tropomyosin 3 | 0.0285656 |
| SMAD3 | SMAD family member 3 | 0.0285189 |
| KLF6 | Kruppel-like factor 6 | 0.0283731 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0280917 |
| PRELID2 | PRELI domain containing 2 | 0.0279563 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0279435 |
| MMP12 | matrix metallopeptidase 12 | 0.0278771 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0274137 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.027213 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0265995 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0261861 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0258794 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0257196 |
| PCNX1 | pecanex 1 | 0.0255728 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0255711 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0255562 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0252983 |
| ZNF217 | zinc finger protein 217 | 0.0252102 |
| SERINC1 | serine incorporator 1 | 0.0249891 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0248146 |
| RPL4 | ribosomal protein L4 | 0.0247237 |
| LDHA | lactate dehydrogenase A | 0.0245701 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0244392 |
| TMEM41B | transmembrane protein 41B | 0.0243821 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0242796 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0242474 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0239647 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0236405 |
| CDCP1 | CUB domain containing protein 1 | 0.0235058 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.023432 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.023382 |
| ANKRD36 | ankyrin repeat domain 36 | 0.023079 |
| CAVIN1 | caveolae associated protein 1 | 0.0229608 |
| MT1X | metallothionein 1X | 0.0228296 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0226087 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit | 0.022397 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.022137 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0220646 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0217504 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0216648 |
| MYOF | myoferlin | 0.0213451 |
| CTTN | cortactin | 0.0212834 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0212764 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0211011 |
| MACROD2 | MACRO domain containing 2 | 0.0209069 |
| ITGA6 | integrin, alpha 6 | 0.0205801 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0203658 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.0201444 |
| PHF20 | PHD finger protein 20 | 0.0197342 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0196535 |
| SRFBP1 | serum response factor binding protein 1 | 0.0194213 |
| RPS2 | ribosomal protein S2 | 0.0193526 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0193484 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0192223 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.019101 |
| FAM199X | family with sequence similarity 199, X-linked | 0.0189643 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0187805 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0185977 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.0185287 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MCL1 | myeloid cell leukemia 1 | -0.0989729 |
| TMSB10 | thymosin beta 10 | -0.0941162 |
| EGR1 | early growth response 1 | -0.0914428 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0751996 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0715971 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0715302 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0677168 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0670337 |
| RPL37 | ribosomal protein L37 | -0.0597061 |
| FBXO11 | F-box protein 11 | -0.056581 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0561143 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.055986 |
| OSMR | oncostatin M receptor | -0.0540046 |
| RPS27 | ribosomal protein S27 | -0.053415 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0513793 |
| RPLP1 | ribosomal protein, large, P1 | -0.051276 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0493175 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0490607 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0484851 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0471762 |
| PCBP2 | poly(rC) binding protein 2 | -0.0460235 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0452403 |
| RPS19 | ribosomal protein S19 | -0.0438226 |
| PTK2 | protein tyrosine kinase 2 | -0.0435623 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0435085 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0432839 |
| HLA-B | major histocompatibility complex, class I, B | -0.0432371 |
| NABP1 | nucleic acid binding protein 1 | -0.0430087 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0428682 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0425499 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0419618 |
| POTEF | POTE ankyrin domain family, member F | -0.0404576 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0398369 |
| RPS6 | ribosomal protein S6 | -0.0393016 |
| RTN4 | reticulon 4 | -0.0388165 |
| IGF2 | insulin-like growth factor 2 | -0.0382878 |
| PDE10A | phosphodiesterase 10A | -0.0379621 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.037602 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0355938 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0345748 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0342885 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0341778 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0341335 |
| TAPBP | TAP binding protein (tapasin) | -0.0338042 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.033752 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0333886 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0331482 |
| PTMS | parathymosin | -0.0327843 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0327703 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0327672 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0323088 |
| KMT2D | lysine (K)-specific methyltransferase 2D | -0.0319918 |
| BRD2 | bromodomain containing 2 | -0.0318384 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0312703 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0299873 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0299391 |
| RBM25 | RNA binding motif protein 25 | -0.0295377 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0294695 |
| RPS29 | ribosomal protein S29 | -0.0293985 |
| ACTN1 | actinin, alpha 1 | -0.0293967 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0293171 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.028117 |
| RSF1 | remodeling and spacing factor 1 | -0.0280356 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0280281 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.027998 |
| PFN1 | profilin 1 | -0.0277407 |
| ZNF644 | zinc finger protein 644 | -0.027629 |
| BSG | basigin (Ok blood group) | -0.0275619 |
| MEF2D | myocyte enhancer factor 2D | -0.0274444 |
| RAB10 | RAB10, member RAS oncogene family | -0.0274434 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0274245 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0266499 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0265839 |
| HLA-A | major histocompatibility complex, class I, A | -0.0265364 |
| BRD4 | bromodomain containing 4 | -0.026486 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.0263662 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0262191 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0260078 |
| YAP1 | Yes-associated protein 1 | -0.0259874 |
| AGRN | agrin | -0.025705 |
| PTMA | prothymosin, alpha | -0.0254657 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0252714 |
| RPS21 | ribosomal protein S21 | -0.0252461 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0247519 |
| MYADM | myeloid-associated differentiation marker | -0.0245319 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0245155 |
| ZNF609 | zinc finger protein 609 | -0.0244978 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0243963 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0243517 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0243186 |
| RPL37A | ribosomal protein L37a | -0.0242255 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0242086 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0240166 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0237182 |
| RNF213 | ring finger protein 213 | -0.0236406 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0235317 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0233997 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0233118 |
| RPL28 | ribosomal protein L28 | -0.0232997 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0232191 |
