| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pyridoxine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.130915 |
| DST | dystonin | 0.12729 |
| SPAG9 | sperm associated antigen 9 | 0.108202 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.103906 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.102996 |
| SLC38A2 | solute carrier family 38, member 2 | 0.102225 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0938814 |
| EGR1 | early growth response 1 | 0.0923749 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.087051 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0857754 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0847074 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0836998 |
| GPHN | gephyrin | 0.0807462 |
| SYT1 | synaptotagmin I | 0.0773466 |
| HDAC9 | histone deacetylase 9 | 0.0763025 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0738172 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0618326 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0617854 |
| MAP1B | microtubule-associated protein 1B | 0.0608054 |
| NAV2 | neuron navigator 2 | 0.0595483 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0571084 |
| LSAMP | limbic system-associated membrane protein | 0.0564054 |
| STC1 | stanniocalcin 1 | 0.0559042 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0557116 |
| HDLBP | high density lipoprotein binding protein | 0.0551492 |
| AHNAK | AHNAK nucleoprotein | 0.0550894 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0535276 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0531457 |
| FLNB | filamin B, beta | 0.051782 |
| FAT1 | FAT atypical cadherin 1 | 0.0510573 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.049771 |
| FNIP1 | folliculin interacting protein 1 | 0.0496417 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0487225 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0486977 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0478428 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0474457 |
| USP34 | ubiquitin specific peptidase 34 | 0.0469104 |
| RPS13 | ribosomal protein S13 | 0.0456055 |
| PTK2 | protein tyrosine kinase 2 | 0.04502 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0448196 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0447665 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0433568 |
| GNAS | GNAS complex locus | 0.042982 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0427334 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0426212 |
| GOLGA4 | golgin A4 | 0.0418353 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.041645 |
| MYO9A | myosin IXA | 0.0415989 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0414038 |
| RORA | RAR-related orphan receptor A | 0.0412045 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0408634 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0407762 |
| MMP12 | matrix metallopeptidase 12 | 0.0399384 |
| INTS6 | integrator complex subunit 6 | 0.0392576 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0374236 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0372224 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0363937 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0361659 |
| RTN4 | reticulon 4 | 0.0352356 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.0343318 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0340681 |
| HMGA2 | high mobility group AT-hook 2 | 0.033901 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0336926 |
| CDH13 | cadherin 13 | 0.033544 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0334677 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0333936 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0332399 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0320303 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0316369 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0314026 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0312109 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0306557 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.029911 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0295198 |
| ATF4 | activating transcription factor 4 | 0.0279456 |
| JUN | jun proto-oncogene | 0.0279377 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0271583 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0266283 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | 0.026438 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0258547 |
| SEPTIN9 | septin 9 | 0.024486 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0244534 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0243505 |
| CDK6 | cyclin-dependent kinase 6 | 0.0236969 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0236059 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0234192 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0233604 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0225878 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0224691 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.02244 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0220881 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0217123 |
| ZNF638 | zinc finger protein 638 | 0.0215468 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0212993 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0212316 |
| PUM1 | pumilio RNA-binding family member 1 | 0.021118 |
| DIAPH2 | diaphanous-related formin 2 | 0.0209226 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0204735 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0202048 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.020072 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.192179 |
| FNDC3B | fibronectin type III domain containing 3B | -0.138266 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.127292 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.113818 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0958276 |
| PRKCA | protein kinase C, alpha | -0.0905832 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0859686 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0858932 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0854656 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0758066 |
| SLTM | SAFB-like, transcription modulator | -0.0748103 |
| TMSB10 | thymosin beta 10 | -0.0739691 |
| EFNA5 | ephrin-A5 | -0.0725221 |
| MCL1 | myeloid cell leukemia 1 | -0.0711142 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0709094 |
| SMYD3 | SET and MYND domain containing 3 | -0.0668525 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0660304 |
| SBF2 | SET binding factor 2 | -0.0633421 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0630364 |
| NFIA | nuclear factor I/A | -0.0612516 |
| PTMA | prothymosin, alpha | -0.0600496 |
| GSK3B | glycogen synthase kinase 3 beta | -0.057684 |
| ATXN1 | ataxin 1 | -0.0546097 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0541205 |
| LMO7 | LIM domain 7 | -0.0539248 |
| MT2A | metallothionein 2A | -0.0533229 |
| RAD51B | RAD51 paralog B | -0.053228 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.053158 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0503447 |
| RPLP1 | ribosomal protein, large, P1 | -0.0495777 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0468517 |
| ANXA2 | annexin A2 | -0.0443257 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.044149 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0427381 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0420073 |
| PKM | pyruvate kinase, muscle | -0.0408602 |
| ITGA6 | integrin, alpha 6 | -0.0407586 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0402561 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0395875 |
| ENO1 | enolase 1, (alpha) | -0.039297 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0373493 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0369748 |
| FMNL2 | formin-like 2 | -0.0367758 |
| FN1 | fibronectin 1 | -0.0353521 |
| RAB10 | RAB10, member RAS oncogene family | -0.0329439 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.031483 |
| RPL37A | ribosomal protein L37a | -0.0313454 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0306628 |
| H3-3B | H3.3 histone B | -0.029141 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0287811 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0285971 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0264297 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.02525 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0248609 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0244051 |
| MYO10 | myosin X | -0.0239906 |
| JMJD1C | jumonji domain containing 1C | -0.0237076 |
| BBX | bobby sox homolog (Drosophila) | -0.022311 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0219301 |
| PGK1 | phosphoglycerate kinase 1 | -0.0219155 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0211347 |
| TAOK1 | TAO kinase 1 | -0.0204252 |
| RPL23 | ribosomal protein L23 | -0.0188732 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0188308 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0187706 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.017111 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0166195 |
| NF1 | neurofibromin 1 | -0.0161157 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0156094 |
| RPS8 | ribosomal protein S8 | -0.0151505 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0149779 |
| GPC6 | glypican 6 | -0.014618 |
| PDE10A | phosphodiesterase 10A | -0.0142887 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0142509 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0138421 |
| ANO6 | anoctamin 6 | -0.0138264 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0134568 |
| ATP13A3 | ATPase type 13A3 | -0.0131 |
| TPM4 | tropomyosin 4 | -0.012773 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0106056 |
| ZNF292 | zinc finger protein 292 | -0.0105012 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.00960453 |
| MYO1E | myosin IE | -0.00946549 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00939077 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00912696 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.00851164 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.00655493 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00642128 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.00572265 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.00488085 |
| NPAS2 | neuronal PAS domain protein 2 | -0.00479342 |
| ASPH | aspartate beta-hydroxylase | -0.00466005 |
| CALR | calreticulin | -0.00416469 |
| MYO1B | myosin IB | -0.00405545 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00399754 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.003334 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.00326473 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.00190799 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.00178435 |
| VIM | vimentin | -0.00165554 |
