| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.0755261 |
| RPS2 | ribosomal protein S2 | 0.0676047 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0333722 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0317825 |
| TXNIP | thioredoxin interacting protein | 0.0309338 |
| NAV2 | neuron navigator 2 | 0.0256008 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.025297 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0249532 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0241469 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0237533 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0221252 |
| CENPF | centromere protein F, 350/400kDa | 0.0201332 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0199128 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0193345 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0181953 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0181677 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0180896 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0180071 |
| DENND5B | DENN/MADD domain containing 5B | 0.0178267 |
| CD47 | CD47 molecule | 0.0170837 |
| TFG | TRK-fused gene | 0.016992 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | 0.0164056 |
| HELZ | helicase with zinc finger | 0.0163858 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.016321 |
| SERINC1 | serine incorporator 1 | 0.0158985 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0153251 |
| MAGED1 | melanoma antigen family D1 | 0.014991 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0146577 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0146229 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0142119 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0141464 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0140869 |
| DENND4A | DENN/MADD domain containing 4A | 0.0137475 |
| TXNRD1 | thioredoxin reductase 1 | 0.0137044 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0136697 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0134325 |
| SON | SON DNA binding protein | 0.013409 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0133517 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.013264 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0129628 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0129372 |
| VRK2 | vaccinia related kinase 2 | 0.0129165 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0127626 |
| KANTR | KDM5C adjacent non-coding transcript | 0.0125089 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0124504 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0122134 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0121966 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0121157 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0120535 |
| LIMD1 | LIM domains containing 1 | 0.0120379 |
| EIF4E | eukaryotic translation initiation factor 4E | 0.0119347 |
| RYBP | RING1 and YY1 binding protein | 0.0117781 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 0.0117208 |
| HLTF | helicase-like transcription factor | 0.0115343 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0114179 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0113963 |
| CKAP5 | cytoskeleton associated protein 5 | 0.011337 |
| TMF1 | TATA element modulatory factor 1 | 0.0113239 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0111902 |
| HMGB2 | high mobility group box 2 | 0.0111695 |
| NDRG1 | N-myc downstream regulated 1 | 0.0111066 |
| XPO6 | exportin 6 | 0.0110663 |
| DIPK2A | divergent protein kinase domain 2A | 0.0110592 |
| ZNF544 | zinc finger protein 544 | 0.0110373 |
| YEATS2 | YEATS domain containing 2 | 0.0110136 |
| RPL38 | ribosomal protein L38 | 0.0109555 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0109201 |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 | 0.0108524 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0108314 |
| RAB18 | RAB18, member RAS oncogene family | 0.0108142 |
| UBE4B | ubiquitination factor E4B | 0.010803 |
| DPY19L3 | dpy-19-like 3 (C. elegans) | 0.0107313 |
| RHOB | ras homolog family member B | 0.010637 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0106012 |
| FANCL | Fanconi anemia, complementation group L | 0.0105208 |
| SNX9 | sorting nexin 9 | 0.0104185 |
| SFTPA2 | surfactant protein A2 | 0.0103466 |
| FERMT2 | fermitin family member 2 | 0.0103352 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0102689 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0101868 |
| SFXN1 | sideroflexin 1 | 0.010152 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0101106 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0101088 |
| ZNF302 | zinc finger protein 302 | 0.0101007 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0100959 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0100257 |
| RIOK3 | RIO kinase 3 | 0.00997923 |
| TET1 | tet methylcytosine dioxygenase 1 | 0.0099246 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.00991686 |
| ZNF451 | zinc finger protein 451 | 0.00989939 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.00981214 |
| NCKAP1 | NCK-associated protein 1 | 0.00971007 |
| CEP70 | centrosomal protein 70kDa | 0.00970623 |
| CREBRF | CREB3 regulatory factor | 0.00970461 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00969727 |
| MYO6 | myosin VI | 0.00967496 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.00964075 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.00961684 |
| PLK2 | polo-like kinase 2 | 0.0096121 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.00959772 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.192241 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175747 |
| FOXP1 | forkhead box P1 | -0.156414 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.13801 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.126557 |
| PTMA | prothymosin, alpha | -0.123568 |
| VCL | vinculin | -0.12083 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.103997 |
| EGFR | epidermal growth factor receptor | -0.0987376 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.08799 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0872996 |
| S100A6 | S100 calcium binding protein A6 | -0.0788887 |
| PKM | pyruvate kinase, muscle | -0.0767992 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0743349 |
| TJP1 | tight junction protein 1 | -0.0724142 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.070331 |
| HDAC9 | histone deacetylase 9 | -0.068284 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0680422 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0637167 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0631433 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0611809 |
| ACTG1 | actin gamma 1 | -0.0588219 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0584161 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0580525 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0564779 |
| JMJD1C | jumonji domain containing 1C | -0.0510873 |
| RPS6 | ribosomal protein S6 | -0.0505932 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0502906 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0500022 |
| CCND1 | cyclin D1 | -0.0487457 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0480452 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0473019 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0469893 |
| NFIA | nuclear factor I/A | -0.0457865 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0421842 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0418292 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.040605 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0405664 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0391299 |
| RPLP1 | ribosomal protein, large, P1 | -0.03899 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0387847 |
| RPLP0 | ribosomal protein, large, P0 | -0.0387684 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0385856 |
| MLIP | muscular LMNA-interacting protein | -0.0377266 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0371194 |
| ZNF438 | zinc finger protein 438 | -0.0364616 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.036077 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0359609 |
| RPL11 | ribosomal protein L11 | -0.0357893 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0356096 |
| POTEF | POTE ankyrin domain family, member F | -0.0340028 |
| S100A4 | S100 calcium binding protein A4 | -0.0337448 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0334565 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0332585 |
| RBM25 | RNA binding motif protein 25 | -0.0332457 |
| GPHN | gephyrin | -0.0330119 |
| RTN4 | reticulon 4 | -0.0326036 |
| RPL27A | ribosomal protein L27a | -0.0323267 |
| EVI5 | ecotropic viral integration site 5 | -0.032261 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.032109 |
| RHOA | ras homolog family member A | -0.0319336 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0306537 |
| LDHA | lactate dehydrogenase A | -0.0303255 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0301885 |
| PRDX2 | peroxiredoxin 2 | -0.0300677 |
| RPS25 | ribosomal protein S25 | -0.0300569 |
| PRELID2 | PRELI domain containing 2 | -0.0298143 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0297858 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0296078 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0295249 |
| RPS19 | ribosomal protein S19 | -0.0292667 |
| RPLP2 | ribosomal protein, large, P2 | -0.029212 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0291033 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0285254 |
| RPS24 | ribosomal protein S24 | -0.028276 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0282419 |
| RPL7A | ribosomal protein L7a | -0.0282253 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0281605 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0280064 |
| PDE7B | phosphodiesterase 7B | -0.0278765 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0277947 |
| CUX1 | cut-like homeobox 1 | -0.0277149 |
| RPL34 | ribosomal protein L34 | -0.027633 |
| GLI3 | GLI family zinc finger 3 | -0.0275647 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0275096 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0274137 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0273906 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0272999 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0271925 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0271471 |
| FER1L6 | fer-1-like family member 6 | -0.0268852 |
| TMSB4X | thymosin beta 4, X-linked | -0.0267494 |
| IGF2 | insulin-like growth factor 2 | -0.0264693 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0263336 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0263074 |
| MEIS2 | Meis homeobox 2 | -0.0258819 |
| RAB7A | RAB7A, member RAS oncogene family | -0.025714 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0257055 |
| RPL13A | ribosomal protein L13a | -0.0254248 |
| SCFD1 | sec1 family domain containing 1 | -0.0254067 |
