| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.082877 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0824852 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0764808 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0696375 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0689836 |
| RPS12 | ribosomal protein S12 | 0.0652195 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0608287 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0573293 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0553722 |
| ARRDC3 | arrestin domain containing 3 | 0.0531293 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0500926 |
| NAV2 | neuron navigator 2 | 0.0487975 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0414028 |
| RPS3 | ribosomal protein S3 | 0.0394328 |
| MSN | moesin | 0.0389451 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0386279 |
| DUSP5 | dual specificity phosphatase 5 | 0.0375873 |
| MT2A | metallothionein 2A | 0.0372682 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0366233 |
| B2M | beta-2-microglobulin | 0.0363773 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0351196 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0335275 |
| RPS2 | ribosomal protein S2 | 0.0335186 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0332236 |
| RPL23 | ribosomal protein L23 | 0.0319615 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0318416 |
| AHNAK | AHNAK nucleoprotein | 0.0317542 |
| RPS19 | ribosomal protein S19 | 0.0310379 |
| VMP1 | vacuole membrane protein 1 | 0.0305436 |
| STC1 | stanniocalcin 1 | 0.0302585 |
| NDRG1 | N-myc downstream regulated 1 | 0.0298061 |
| AFDN | afadin, adherens junction formation factor | 0.0286549 |
| PRELID2 | PRELI domain containing 2 | 0.0285812 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.028062 |
| RPL37A | ribosomal protein L37a | 0.0263046 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0259134 |
| MYOF | myoferlin | 0.0257937 |
| YEATS2 | YEATS domain containing 2 | 0.0255826 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.025212 |
| RPS23 | ribosomal protein S23 | 0.0249568 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0247689 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0246222 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0244086 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0237701 |
| SMAD3 | SMAD family member 3 | 0.0236657 |
| ANO6 | anoctamin 6 | 0.0229418 |
| OGA | O-GlcNAcase | 0.0225562 |
| RPS10 | ribosomal protein S10 | 0.0222751 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0221421 |
| RUNX1 | runt-related transcription factor 1 | 0.0220891 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0219404 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0219308 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0218269 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0216988 |
| ATP13A3 | ATPase type 13A3 | 0.0216343 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0215427 |
| TXNIP | thioredoxin interacting protein | 0.02152 |
| TGM2 | transglutaminase 2 | 0.0215023 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0213823 |
| NGLY1 | N-glycanase 1 | 0.0213102 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0211 |
| RASA2 | RAS p21 protein activator 2 | 0.0210909 |
| DSPP | dentin sialophosphoprotein | 0.0207832 |
| EHBP1 | EH domain binding protein 1 | 0.0204636 |
| MED13L | mediator complex subunit 13-like | 0.0202824 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0202733 |
| PDE10A | phosphodiesterase 10A | 0.0196363 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0196155 |
| SEPTIN9 | septin 9 | 0.0193113 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0192732 |
| PLPP3 | phospholipid phosphatase 3 | 0.0189909 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0187598 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0187499 |
| RPS17 | ribosomal protein S17 | 0.0186388 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0186289 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0184333 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0180872 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0177848 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0176718 |
| RPS15 | ribosomal protein S15 | 0.0175401 |
| RPL18 | ribosomal protein L18 | 0.0173478 |
| PCBP3 | poly(rC) binding protein 3 | 0.0171052 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0168162 |
| CMIP | c-Maf inducing protein | 0.0163675 |
| ZNF451 | zinc finger protein 451 | 0.0162019 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0161823 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0161759 |
| RPL32 | ribosomal protein L32 | 0.0160032 |
| RPS6 | ribosomal protein S6 | 0.0159977 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0159119 |
| RPLP2 | ribosomal protein, large, P2 | 0.0158336 |
| CCNL1 | cyclin L1 | 0.0157576 |
| DGKH | diacylglycerol kinase, eta | 0.0157421 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0156868 |
| OSMR | oncostatin M receptor | 0.0156138 |
| RPS4X | ribosomal protein S4, X-linked | 0.0153497 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0153494 |
| CD109 | CD109 molecule | 0.0153397 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0151605 |
| FAM3C | family with sequence similarity 3, member C | 0.0151073 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.280191 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.140074 |
| IER3 | immediate early response 3 | -0.110748 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.096896 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0915491 |
| FN1 | fibronectin 1 | -0.0869043 |
| VCL | vinculin | -0.0854091 |
| CDH13 | cadherin 13 | -0.0838529 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0808554 |
| FRMD4A | FERM domain containing 4A | -0.0801598 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.075391 |
| HLA-B | major histocompatibility complex, class I, B | -0.0687001 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0676906 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0665477 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0650626 |
| CTSD | cathepsin D | -0.0608492 |
| COL1A1 | collagen, type I, alpha 1 | -0.0600335 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0595772 |
| TMSB4X | thymosin beta 4, X-linked | -0.0590726 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0585533 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0572166 |
| HLA-E | major histocompatibility complex, class I, E | -0.0567131 |
| GLIS3 | GLIS family zinc finger 3 | -0.0565163 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0541286 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0539049 |
| SQSTM1 | sequestosome 1 | -0.0520744 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0519814 |
| BICC1 | BicC family RNA binding protein 1 | -0.050438 |
| HDAC9 | histone deacetylase 9 | -0.0503629 |
| ACTG1 | actin gamma 1 | -0.050187 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0500759 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0494765 |
| JUN | jun proto-oncogene | -0.0494168 |
| EGR1 | early growth response 1 | -0.0482164 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0477477 |
| PLIN2 | perilipin 2 | -0.0470416 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.046958 |
| RND3 | Rho family GTPase 3 | -0.0465651 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0462961 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0450089 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0443481 |
| SP100 | SP100 nuclear antigen | -0.0432099 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0428189 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0415758 |
| DST | dystonin | -0.0410778 |
| TPM4 | tropomyosin 4 | -0.0403199 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0398238 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0397546 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0394755 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.03942 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0392649 |
| CANX | calnexin | -0.0392273 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0384344 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0380221 |
| NRN1 | neuritin 1 | -0.0379923 |
| CALR | calreticulin | -0.0379661 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0371349 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0367705 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0366622 |
| CALD1 | caldesmon 1 | -0.0361764 |
| HMGA2 | high mobility group AT-hook 2 | -0.035982 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0357627 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0352391 |
| CTSB | cathepsin B | -0.0350884 |
| PTMA | prothymosin, alpha | -0.0350313 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0349906 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0348056 |
| FTL | ferritin, light polypeptide | -0.0335775 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0335261 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0334477 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0333591 |
| DIAPH2 | diaphanous-related formin 2 | -0.0329763 |
| CAVIN1 | caveolae associated protein 1 | -0.0320367 |
| HLA-A | major histocompatibility complex, class I, A | -0.0316554 |
| C3 | complement component 3 | -0.031537 |
| TPM1 | tropomyosin 1 (alpha) | -0.0314814 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0310594 |
| GNAS | GNAS complex locus | -0.0309857 |
| COL1A2 | collagen, type I, alpha 2 | -0.0309766 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0304493 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0299501 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.029575 |
| NAV1 | neuron navigator 1 | -0.0293735 |
| RPS24 | ribosomal protein S24 | -0.0293124 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0291586 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.0285416 |
| TUBB | tubulin, beta class I | -0.0281558 |
| KRT19 | keratin 19, type I | -0.0278149 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0273846 |
| TENM2 | teneurin transmembrane protein 2 | -0.0273072 |
| RPLP0 | ribosomal protein, large, P0 | -0.0272968 |
| PALLD | palladin, cytoskeletal associated protein | -0.0270352 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0265309 |
| RAI14 | retinoic acid induced 14 | -0.0264207 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0263274 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0262946 |
| ERBIN | erbb2 interacting protein | -0.0262344 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0260898 |
| RAD51B | RAD51 paralog B | -0.0250172 |
| CLIC4 | chloride intracellular channel 4 | -0.0249608 |
