| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pyridoxine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.179311 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.169332 |
| FAM13A | family with sequence similarity 13, member A | 0.0821655 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0766411 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0742111 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0740552 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0725728 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0702672 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0693421 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0684767 |
| NRXN3 | neurexin 3 | 0.0683882 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0665198 |
| EGFR | epidermal growth factor receptor | 0.0646194 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0618325 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0598332 |
| ARRDC3 | arrestin domain containing 3 | 0.0589571 |
| NDRG1 | N-myc downstream regulated 1 | 0.0573886 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0537655 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0536266 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0512381 |
| SEC24A | SEC24 family member A | 0.0490815 |
| HIP1 | huntingtin interacting protein 1 | 0.0461053 |
| COG5 | component of oligomeric golgi complex 5 | 0.0459214 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0452996 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0450271 |
| GOLGA4 | golgin A4 | 0.0449349 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0442814 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0439748 |
| CANX | calnexin | 0.0432917 |
| LOXL2 | lysyl oxidase-like 2 | 0.0426068 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0425645 |
| ATP13A3 | ATPase type 13A3 | 0.0418686 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0416831 |
| OGA | O-GlcNAcase | 0.0415728 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0411394 |
| HELZ | helicase with zinc finger | 0.040588 |
| MEF2A | myocyte enhancer factor 2A | 0.0405712 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0397048 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0395762 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0392332 |
| MATR3 | matrin 3 | 0.037909 |
| NCOR1 | nuclear receptor corepressor 1 | 0.037254 |
| ITGAV | integrin, alpha V | 0.0367341 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0359144 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0354948 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0354258 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0352631 |
| SPAG9 | sperm associated antigen 9 | 0.0351988 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0349835 |
| AHNAK | AHNAK nucleoprotein | 0.0349444 |
| SETD5 | SET domain containing 5 | 0.0343256 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0341926 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0341652 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0340075 |
| SRP54 | signal recognition particle 54kDa | 0.033963 |
| SEC24D | SEC24 family member D | 0.0337922 |
| CUL3 | cullin 3 | 0.0337547 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0336649 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0332378 |
| RND3 | Rho family GTPase 3 | 0.0331948 |
| ANXA5 | annexin A5 | 0.0330768 |
| CD44 | CD44 molecule (Indian blood group) | 0.0329566 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0327307 |
| TPM3 | tropomyosin 3 | 0.0326513 |
| MYOF | myoferlin | 0.0323051 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0319284 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0316634 |
| SEPTIN2 | septin 2 | 0.0315836 |
| MT2A | metallothionein 2A | 0.0313227 |
| RBM39 | RNA binding motif protein 39 | 0.0311519 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0309606 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0306283 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0304259 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0304106 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.030325 |
| FNIP1 | folliculin interacting protein 1 | 0.0301219 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0300534 |
| WDR41 | WD repeat domain 41 | 0.0299978 |
| BPTF | bromodomain PHD finger transcription factor | 0.0297702 |
| C1D | C1D nuclear receptor corepressor | 0.0295503 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.029297 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.029259 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.029124 |
| ZNF207 | zinc finger protein 207 | 0.028967 |
| PRELID2 | PRELI domain containing 2 | 0.0287755 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0287539 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0287419 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0287124 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0285549 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0284467 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0283266 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0283237 |
| NBAS | neuroblastoma amplified sequence | 0.027891 |
| ADM | adrenomedullin | 0.0278696 |
| RAB10 | RAB10, member RAS oncogene family | 0.0278008 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.027609 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0274143 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.027391 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0272934 |
| ZNF654 | zinc finger protein 654 | 0.0271496 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.109083 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.105879 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.101268 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0939972 |
| COL1A2 | collagen, type I, alpha 2 | -0.0840141 |
| TMSB10 | thymosin beta 10 | -0.07989 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0777151 |
| HMGA2 | high mobility group AT-hook 2 | -0.066861 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0653572 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0606872 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0567462 |
| IL6 | interleukin 6 | -0.0528105 |
| POTEF | POTE ankyrin domain family, member F | -0.0514664 |
| ACTG1 | actin gamma 1 | -0.0490048 |
| FN1 | fibronectin 1 | -0.0457234 |
| CALR | calreticulin | -0.0417349 |
| LDHA | lactate dehydrogenase A | -0.0410186 |
| TNS3 | tensin 3 | -0.0405395 |
| LOX | lysyl oxidase | -0.0401714 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0401345 |
| TNNC1 | troponin C type 1 (slow) | -0.0376968 |
| FBN1 | fibrillin 1 | -0.035515 |
| TUBB | tubulin, beta class I | -0.034842 |
| H3-3B | H3.3 histone B | -0.0342905 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0313732 |
| HLA-B | major histocompatibility complex, class I, B | -0.0309703 |
| HMGB1 | high mobility group box 1 | -0.0308829 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0308229 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0305979 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0305163 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0294695 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0293028 |
| TUBA1B | tubulin, alpha 1b | -0.0288746 |
| RPLP1 | ribosomal protein, large, P1 | -0.0285054 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0284401 |
| COL5A2 | collagen, type V, alpha 2 | -0.0283652 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0282252 |
| BSG | basigin (Ok blood group) | -0.0280149 |
| PALLD | palladin, cytoskeletal associated protein | -0.0278029 |
| TPX2 | TPX2, microtubule-associated | -0.0277099 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0275594 |
| PTMA | prothymosin, alpha | -0.027291 |
| B2M | beta-2-microglobulin | -0.0272008 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0266977 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0262934 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0262014 |
| EFHD2 | EF-hand domain family, member D2 | -0.0258497 |
| CST3 | cystatin C | -0.0258464 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0250106 |
| MAP1B | microtubule-associated protein 1B | -0.0246108 |
| CCND1 | cyclin D1 | -0.0245694 |
| CCNI | cyclin I | -0.024319 |
| ZFHX3 | zinc finger homeobox 3 | -0.0242851 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0241124 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0238038 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.023762 |
| RIGI | RNA sensor RIG-I | -0.0235458 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0235387 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0233443 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | -0.0231086 |
| TANK | TRAF family member-associated NFKB activator | -0.0228612 |
| BBX | bobby sox homolog (Drosophila) | -0.0228419 |
| RPL28 | ribosomal protein L28 | -0.0223687 |
| S100A6 | S100 calcium binding protein A6 | -0.0221635 |
| MMP2 | matrix metallopeptidase 2 | -0.0219478 |
| FTL | ferritin, light polypeptide | -0.0216947 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0216932 |
| YY1 | YY1 transcription factor | -0.0215002 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0214172 |
| FUS | FUS RNA binding protein | -0.0214041 |
| RPS11 | ribosomal protein S11 | -0.0212986 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0212801 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0210696 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0210151 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0209088 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0207595 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0206789 |
| ERGIC2 | ERGIC and golgi 2 | -0.020585 |
| CENPE | centromere protein E, 312kDa | -0.0205689 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.0204621 |
| TMSB4X | thymosin beta 4, X-linked | -0.0204435 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.0204134 |
| RPL34 | ribosomal protein L34 | -0.0203969 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0202172 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.0200424 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0200347 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0200064 |
| GOLIM4 | golgi integral membrane protein 4 | -0.0199528 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0198959 |
| GUK1 | guanylate kinase 1 | -0.0198255 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0197993 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0197367 |
| RSPRY1 | ring finger and SPRY domain containing 1 | -0.0196572 |
| KLF10 | Kruppel-like factor 10 | -0.0196249 |
| EGR1 | early growth response 1 | -0.0195869 |
| CWC27 | CWC27 spliceosome-associated protein homolog (S. cerevisiae) | -0.0194433 |
| PBRM1 | polybromo 1 | -0.019428 |
| RPL7 | ribosomal protein L7 | -0.0194164 |
| RPS14 | ribosomal protein S14 | -0.0193084 |
| NABP1 | nucleic acid binding protein 1 | -0.0192993 |
