| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pyridoxine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pyridoxine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.190433 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.110607 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0808646 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0696232 |
| ANXA1 | annexin A1 | 0.0603498 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0541152 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0535774 |
| PTMA | prothymosin, alpha | 0.049983 |
| GOLGA4 | golgin A4 | 0.0499265 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0477045 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0454581 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0450042 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0424912 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0422893 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0421751 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0418971 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0416764 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0408174 |
| SQSTM1 | sequestosome 1 | 0.0406213 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0391662 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0381465 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0366419 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0365978 |
| TXNIP | thioredoxin interacting protein | 0.0356937 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0355723 |
| SPAG9 | sperm associated antigen 9 | 0.0347812 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0347206 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0334825 |
| SEC24A | SEC24 family member A | 0.0334204 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0331781 |
| MORF4L2 | mortality factor 4 like 2 | 0.0326779 |
| CCDC88A | coiled-coil domain containing 88A | 0.0326581 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0318417 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0316521 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0303452 |
| YBX3 | Y box binding protein 3 | 0.0293794 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0290622 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0288647 |
| TXNRD1 | thioredoxin reductase 1 | 0.028166 |
| EGFR | epidermal growth factor receptor | 0.0280795 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0278563 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0276121 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.027448 |
| POTEF | POTE ankyrin domain family, member F | 0.0271733 |
| PKM | pyruvate kinase, muscle | 0.027133 |
| COG6 | component of oligomeric golgi complex 6 | 0.0270689 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0269908 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0269151 |
| CCNL1 | cyclin L1 | 0.0266599 |
| TAOK3 | TAO kinase 3 | 0.025899 |
| INTS6 | integrator complex subunit 6 | 0.0257925 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0256292 |
| AHR | aryl hydrocarbon receptor | 0.0252023 |
| RPS6 | ribosomal protein S6 | 0.0250654 |
| QKI | QKI, KH domain containing, RNA binding | 0.0250179 |
| RPS3 | ribosomal protein S3 | 0.024977 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0248196 |
| UFL1 | UFM1-specific ligase 1 | 0.0248094 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0248078 |
| CALU | calumenin | 0.0247104 |
| COPA | coatomer protein complex, subunit alpha | 0.0245351 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0243759 |
| TAOK1 | TAO kinase 1 | 0.0242982 |
| ABHD3 | abhydrolase domain containing 3 | 0.0242695 |
| CALR | calreticulin | 0.0241964 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0239172 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0236947 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0235857 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0233283 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0233135 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0232259 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0231366 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0231161 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0228774 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0228615 |
| GOLGB1 | golgin B1 | 0.0225177 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0225122 |
| MYOF | myoferlin | 0.02247 |
| B2M | beta-2-microglobulin | 0.0224521 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0224025 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0221914 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0220469 |
| NKTR | natural killer cell triggering receptor | 0.0220184 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0218924 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0213731 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0212567 |
| SRPK2 | SRSF protein kinase 2 | 0.0212187 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0210836 |
| CEP44 | centrosomal protein 44kDa | 0.0210808 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0210399 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0208063 |
| RPLP0 | ribosomal protein, large, P0 | 0.0206486 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0206395 |
| ZNF638 | zinc finger protein 638 | 0.0206126 |
| NF1 | neurofibromin 1 | 0.0205481 |
| CSPP1 | centrosome and spindle pole associated protein 1 | 0.0205294 |
| TMEM263 | transmembrane protein 263 | 0.0204645 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0201857 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0201765 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0201087 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OSMR | oncostatin M receptor | -0.0908223 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.075926 |
| AHNAK | AHNAK nucleoprotein | -0.0689876 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0637092 |
| SMYD3 | SET and MYND domain containing 3 | -0.0616369 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0553728 |
| HMGA2 | high mobility group AT-hook 2 | -0.0530503 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0507343 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0495972 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0484671 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0445028 |
| SMAD3 | SMAD family member 3 | -0.0417518 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0403859 |
| CDCP1 | CUB domain containing protein 1 | -0.0395384 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0394592 |
| VCL | vinculin | -0.0391831 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0390372 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0387761 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0387096 |
| SVIL | supervillin | -0.0379041 |
| SDC4 | syndecan 4 | -0.0373336 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0370741 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0368385 |
| VIM | vimentin | -0.0366575 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0365464 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0359873 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0356181 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0352734 |
| PRELID2 | PRELI domain containing 2 | -0.0351139 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0346023 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0346012 |
| SEPTIN9 | septin 9 | -0.033414 |
| NAV2 | neuron navigator 2 | -0.0326569 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0325387 |
| AOPEP | aminopeptidase O (putative) | -0.0323042 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0322114 |
| IER3 | immediate early response 3 | -0.0318269 |
| AEBP2 | AE binding protein 2 | -0.0311527 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0307332 |
| TCF12 | transcription factor 12 | -0.0306778 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0305451 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0303835 |
| LDHA | lactate dehydrogenase A | -0.0298625 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0290247 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0289354 |
| RNF213 | ring finger protein 213 | -0.0287898 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0287162 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0286274 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0282209 |
| KIAA1328 | KIAA1328 | -0.0275898 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0271651 |
| FMN1 | formin 1 | -0.0271053 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0270426 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0270312 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0268031 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0267688 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0265805 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0262629 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0258232 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0258136 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0256075 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0251534 |
| PTK2 | protein tyrosine kinase 2 | -0.0247529 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0247165 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0247164 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0240601 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0240517 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0239946 |
| RAD51B | RAD51 paralog B | -0.0239728 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0239418 |
| PRKCA | protein kinase C, alpha | -0.0239184 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0234378 |
| PGK1 | phosphoglycerate kinase 1 | -0.0233463 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0233155 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0231974 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0231811 |
| CEP112 | centrosomal protein 112kDa | -0.0231546 |
| RAI14 | retinoic acid induced 14 | -0.0230977 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0224777 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0224187 |
| CENPP | centromere protein P | -0.022254 |
| RBM39 | RNA binding motif protein 39 | -0.0221896 |
| ANXA2 | annexin A2 | -0.0221577 |
| ZNF292 | zinc finger protein 292 | -0.0219756 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0219706 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0218222 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0216655 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.0215654 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.021414 |
| RPL4 | ribosomal protein L4 | -0.0211911 |
| WDR33 | WD repeat domain 33 | -0.0211715 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0210683 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0210265 |
| COL5A1 | collagen, type V, alpha 1 | -0.0209607 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0209595 |
| PRPF6 | pre-mRNA processing factor 6 | -0.0209561 |
| DST | dystonin | -0.0209379 |
| ATXN7L1 | ataxin 7-like 1 | -0.0206899 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | -0.0205118 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.020425 |
