Quadriplegia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

233 genes co-occuring with the disease Quadriplegia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
MOG myelin oligodendrocyte glycoprotein 2.805
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 2.567
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 2.448
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 2.406
AP4B1 adaptor-related protein complex 4, beta 1 subunit 2.401
AP4M1 adaptor-related protein complex 4, mu 1 subunit 2.396
MBP myelin basic protein 2.329
CRP C-reactive protein, pentraxin-related 2.025
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.023
ALB albumin 2.01
IL6 interleukin 6 1.959
GFAP glial fibrillary acidic protein 1.927
CD4 CD4 molecule 1.884
KCNJ18 potassium channel, inwardly rectifying subfamily J, member 18 1.881
TRAPPC2L trafficking protein particle complex 2-like 1.862
BDNF brain-derived neurotrophic factor 1.858
NFASC neurofascin 1.851
IFNG interferon, gamma 1.84
AIF1 allograft inflammatory factor 1 1.838
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.836
CKB creatine kinase, brain 1.832
CKMT1B creatine kinase, mitochondrial 1B 1.831
CKM creatine kinase, muscle 1.827
SOD1 superoxide dismutase 1, soluble 1.808
INS insulin 1.8
TNF tumor necrosis factor 1.793
IL17A interleukin 17A 1.791
PTPRC protein tyrosine phosphatase, receptor type, C 1.78
SCN4A sodium channel, voltage gated, type IV alpha subunit 1.763
IL1B interleukin 1, beta 1.76
IL10 interleukin 10 1.756
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.755
MAG myelin associated glycoprotein 1.753
OMG oligodendrocyte myelin glycoprotein 1.75
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.715
NTF3 neurotrophin 3 1.681
TUBA1A tubulin, alpha 1a 1.68
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1.675
AOC3 amine oxidase, copper containing 3 1.673
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 1.667
F2 coagulation factor II (thrombin) 1.666
CD8A CD8a molecule 1.657
NGF nerve growth factor (beta polypeptide) 1.635
PLP1 proteolipid protein 1 1.63
KANK1 KN motif and ankyrin repeat domains 1 1.62
MYH14 myosin, heavy chain 14, non-muscle 1.6
CNTNAP1 contactin associated protein 1 1.591
SPG11 spastic paraplegia 11 (autosomal recessive) 1.572
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.57
HMBS hydroxymethylbilane synthase 1.564
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 1.558
CNTF ciliary neurotrophic factor 1.558
PXDNL peroxidasin-like 1.541
AVP arginine vasopressin 1.539
PXDN peroxidasin 1.539
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 1.539
FOXP3 forkhead box P3 1.53
RTN4 reticulon 4 1.517
TEPSIN TEPSIN adaptor related protein complex 4 accessory protein 1.516
NEFH neurofilament, heavy polypeptide 1.508
IL4 interleukin 4 1.507
GDNF glial cell derived neurotrophic factor 1.507
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 1.505
F3 coagulation factor III (thromboplastin, tissue factor) 1.503
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.502
REN renin 1.502
TGFB1 transforming growth factor, beta 1 1.484
CNTN1 contactin 1 1.48
PLAT plasminogen activator, tissue 1.475
IL2 interleukin 2 1.474
CPZ carboxypeptidase Z 1.472
RNASEH2B ribonuclease H2, subunit B 1.464
CD19 CD19 molecule 1.454
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 1.446
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 1.445
ARSA arylsulfatase A 1.439
GJC2 gap junction protein, gamma 2, 47kDa 1.438
CCL2 chemokine (C-C motif) ligand 2 1.436
STXBP1 syntaxin binding protein 1 1.421
OLIG2 oligodendrocyte lineage transcription factor 2 1.413
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.412
ACTB actin, beta 1.412
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 1.403
IGF1 insulin-like growth factor 1 (somatomedin C) 1.396
ALAS1 5'-aminolevulinate synthase 1 1.396
BTD biotinidase 1.395
TUBB4A tubulin, beta 4A class IVa 1.394
IFNB1 interferon, beta 1, fibroblast 1.381
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.362
ACE2 angiotensin I converting enzyme 2 1.359
MB myoglobin 1.354
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 1.353
GALC galactosylceramidase 1.351
ACE angiotensin I converting enzyme 1.351
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.348
CD68 CD68 molecule 1.346
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.336
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.317
COL4A1 collagen, type IV, alpha 1 1.315
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 1.297
FA2H fatty acid 2-hydroxylase 1.295
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.29
IL1A interleukin 1, alpha 1.284
SUMF1 sulfatase modifying factor 1 1.284
PNPLA6 patatin-like phospholipase domain containing 6 1.278
CD69 CD69 molecule 1.277
CXCL10 chemokine (C-X-C motif) ligand 10 1.275
POMC proopiomelanocortin 1.262
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.262
SELL selectin L 1.26
FGF2 fibroblast growth factor 2 (basic) 1.254
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.25
TRAPPC11 trafficking protein particle complex 11 1.246
ARG1 arginase 1 1.245
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 1.244
NTF4 neurotrophin 4 1.242
PTH parathyroid hormone 1.238
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.236
TMEM119 transmembrane protein 119 1.236
TPGS1 tubulin polyglutamylase complex subunit 1 1.235
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.235
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.235
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) 1.233
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 1.233
THY1 Thy-1 cell surface antigen 1.232
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 1.232
RNASEH2C ribonuclease H2, subunit C 1.228
ZC4H2 zinc finger, C4H2 domain containing 1.227
KIF1A kinesin family member 1A 1.227
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 1.224
TBX21 T-box 21 1.222
NES nestin 1.22
TLR4 toll-like receptor 4 1.218
FGF17 fibroblast growth factor 17 1.217
DNAH8 dynein, axonemal, heavy chain 8 1.217
RGCC regulator of cell cycle 1.217
CCL3 chemokine (C-C motif) ligand 3 1.216
TRAPPC1 trafficking protein particle complex 1 1.21
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 1.208
CD44 CD44 molecule (Indian blood group) 1.201
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.198
CD28 CD28 molecule 1.195
TUBB2B tubulin, beta 2B class IIb 1.194
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.192
LRRC24 leucine rich repeat containing 24 1.191
KCNT1 potassium channel, sodium activated subfamily T, member 1 1.191
LRRC14 leucine rich repeat containing 14 1.19
CSF3 colony stimulating factor 3 (granulocyte) 1.189
GAP43 growth associated protein 43 1.187
CNTNAP2 contactin associated protein-like 2 1.187
TARDBP TAR DNA binding protein 1.184
ERI1 exoribonuclease 1 1.183
CCL5 chemokine (C-C motif) ligand 5 1.176
OR5H15 olfactory receptor, family 5, subfamily H, member 15 1.175
S100B S100 calcium binding protein B 1.173
FGF4 fibroblast growth factor 4 1.172
FGF22 fibroblast growth factor 22 1.17
IL13 interleukin 13 1.162
RTN4R reticulon 4 receptor 1.16
CXCL8 chemokine (C-X-C motif) ligand 8 1.159
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 1.158
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 1.157
FGF10 fibroblast growth factor 10 1.154
CD86 CD86 molecule 1.152
PIBF1 progesterone immunomodulatory binding factor 1 1.15
TRAPPC4 trafficking protein particle complex 4 1.148
FGF18 fibroblast growth factor 18 1.146
NEFL neurofilament, light polypeptide 1.14
FGF9 fibroblast growth factor 9 1.137
TRAPPC8 trafficking protein particle complex 8 1.136
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 1.132
GALNS galactosamine (N-acetyl)-6-sulfatase 1.129
FGF3 fibroblast growth factor 3 1.126
FGF6 fibroblast growth factor 6 1.125
FGF16 fibroblast growth factor 16 1.125
SPAST spastin 1.124
PNKP polynucleotide kinase 3'-phosphatase 1.123
FGF20 fibroblast growth factor 20 1.123
TRAPPC12 trafficking protein particle complex 12 1.117
FGF5 fibroblast growth factor 5 1.117
FN1 fibronectin 1 1.117
FGF7 fibroblast growth factor 7 1.116
MAPT microtubule-associated protein tau 1.116
SETX senataxin 1.116
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.115
ENO2 enolase 2 (gamma, neuronal) 1.114
RNASEH2A ribonuclease H2, subunit A 1.112
ENG endoglin 1.11
TAC1 tachykinin, precursor 1 1.107
PRUNE1 prune exopolyphosphatase 1 1.104
FGF8 fibroblast growth factor 8 (androgen-induced) 1.102
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 1.101
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.097
MMP9 matrix metallopeptidase 9 1.096
ALAD aminolevulinate dehydratase 1.093
CDKL5 cyclin-dependent kinase-like 5 1.091
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.089
SMAD9 SMAD family member 9 1.084
EPO erythropoietin 1.083
IFNA1 interferon, alpha 1 1.083
DENND2A DENN/MADD domain containing 2A 1.081
UBQLN2 ubiquilin 2 1.079
NCAN neurocan 1.079
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.079
ATAD3A ATPase family, AAA domain containing 3A 1.071
PPP6R3 protein phosphatase 6, regulatory subunit 3 1.07
SPPL2A signal peptide peptidase like 2A 1.069
SCN1A sodium channel, voltage gated, type I alpha subunit 1.067
FUS FUS RNA binding protein 1.063
MAP2 microtubule-associated protein 2 1.061
NCAM1 neural cell adhesion molecule 1 1.061
CHAT choline O-acetyltransferase 1.06
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 1.06
JUN jun proto-oncogene 1.06
OR2G3 olfactory receptor, family 2, subfamily G, member 3 1.057
C19ORF12 chromosome 19 open reading frame 12 1.054
TTLL1 tubulin tyrosine ligase-like family member 1 1.054
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 1.051
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.047
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.045
PRRT2 proline-rich transmembrane protein 2 1.045
NAGS N-acetylglutamate synthase 1.045
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.036
RHOBTB2 Rho-related BTB domain containing 2 1.035
CD34 CD34 molecule 1.034
PLG plasminogen 1.034
LGI1 leucine-rich, glioma inactivated 1 1.02
C9ORF72 chromosome 9 open reading frame 72 1.016
AMPH amphiphysin 1.014
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.008
FIG4 FIG4 phosphoinositide 5-phosphatase 1.006
TAAR6 trace amine associated receptor 6 1.005
WASHC5 WASH complex subunit 5 1.002