| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Quinestrol perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Quinestrol_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.13757 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.100287 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.085829 |
| AREG | amphiregulin | 0.0789348 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0582039 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0563088 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0530845 |
| RPS12 | ribosomal protein S12 | 0.0530843 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0478748 |
| RRM2 | ribonucleotide reductase M2 | 0.0464278 |
| RTN4 | reticulon 4 | 0.0417118 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0409756 |
| TPM3 | tropomyosin 3 | 0.0361894 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0359074 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0327787 |
| ASPH | aspartate beta-hydroxylase | 0.0304908 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.029344 |
| YBX3 | Y box binding protein 3 | 0.0282779 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0282644 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.028219 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0276403 |
| RPS2 | ribosomal protein S2 | 0.0269125 |
| RPS3 | ribosomal protein S3 | 0.0268834 |
| GANAB | glucosidase, alpha; neutral AB | 0.0262528 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0260095 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0253812 |
| TMEM41B | transmembrane protein 41B | 0.024346 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0228843 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0225804 |
| YTHDC1 | YTH domain containing 1 | 0.0219159 |
| SET | SET nuclear proto-oncogene | 0.021671 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0211111 |
| UBC | ubiquitin C | 0.0199537 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0199176 |
| CLTC | clathrin, heavy chain (Hc) | 0.019656 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0196334 |
| PCBP2 | poly(rC) binding protein 2 | 0.0194649 |
| SPAG9 | sperm associated antigen 9 | 0.0191464 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | 0.0184995 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0184602 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0181955 |
| EZR | ezrin | 0.0178778 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0177362 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0176201 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0168233 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0168065 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0167061 |
| RPL9 | ribosomal protein L9 | 0.0166524 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0163195 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0159433 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0155651 |
| RFLNA | refilin A | 0.0155586 |
| SERINC1 | serine incorporator 1 | 0.0152626 |
| CEP95 | centrosomal protein 95kDa | 0.015016 |
| RPL26 | ribosomal protein L26 | 0.0150009 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0148231 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0146662 |
| YBX1 | Y box binding protein 1 | 0.0142576 |
| BRD2 | bromodomain containing 2 | 0.01423 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0141974 |
| CLDND1 | claudin domain containing 1 | 0.0140658 |
| JMJD1C | jumonji domain containing 1C | 0.0139888 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0138767 |
| MAGEA4 | melanoma antigen family A4 | 0.0137144 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0136191 |
| MCL1 | myeloid cell leukemia 1 | 0.0136107 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0135717 |
| ARRDC3 | arrestin domain containing 3 | 0.0135128 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0134067 |
| ADM | adrenomedullin | 0.0132614 |
| MSH6 | mutS homolog 6 | 0.013237 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0132215 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0131145 |
| NSUN2 | NOP2/Sun RNA methyltransferase family, member 2 | 0.0130916 |
| TJP1 | tight junction protein 1 | 0.0130892 |
| STK4 | serine/threonine kinase 4 | 0.0128478 |
| RPS27A | ribosomal protein S27a | 0.0128417 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0126512 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0125697 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0125394 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0124984 |
| ITSN2 | intersectin 2 | 0.012457 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.012382 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0123646 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0122638 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.012248 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0122366 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0122277 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0122261 |
| ARF4 | ADP-ribosylation factor 4 | 0.0121304 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.012097 |
| DSPP | dentin sialophosphoprotein | 0.0120631 |
| CDC37 | cell division cycle 37 | 0.01201 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0118993 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0118888 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0118728 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0117987 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0117978 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0116597 |
| CCNL1 | cyclin L1 | 0.0115083 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.303739 |
| NLGN1 | neuroligin 1 | -0.267688 |
| VIM | vimentin | -0.174209 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.168814 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.126822 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124845 |
| MMP12 | matrix metallopeptidase 12 | -0.116644 |
| PCDH7 | protocadherin 7 | -0.105023 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.104771 |
| FTL | ferritin, light polypeptide | -0.0881699 |
| RPLP1 | ribosomal protein, large, P1 | -0.0815665 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0734975 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0707156 |
| TENM3 | teneurin transmembrane protein 3 | -0.0706375 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.069367 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0680783 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0593895 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0557501 |
| NHSL1 | NHS-like 1 | -0.0522807 |
| SYT1 | synaptotagmin I | -0.049652 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0494809 |
| RPS6 | ribosomal protein S6 | -0.0480539 |
| HMGA2 | high mobility group AT-hook 2 | -0.0437683 |
| RASAL2 | RAS protein activator like 2 | -0.0428629 |
| NEBL | nebulette | -0.0420999 |
| RPL19 | ribosomal protein L19 | -0.0412105 |
| CCN2 | cellular communication network factor 2 | -0.0402874 |
| CCND1 | cyclin D1 | -0.0378469 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0378159 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0372684 |
| KIF5B | kinesin family member 5B | -0.0360543 |
| RPS16 | ribosomal protein S16 | -0.0359922 |
| PTMA | prothymosin, alpha | -0.0357529 |
| ZNF804A | zinc finger protein 804A | -0.0355663 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0352702 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0344477 |
| RPS19 | ribosomal protein S19 | -0.0343597 |
| CLDN1 | claudin 1 | -0.0341465 |
| EHBP1 | EH domain binding protein 1 | -0.0337575 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0335148 |
| MGAT4C | MGAT4 family, member C | -0.0333517 |
| HSPB1 | heat shock 27kDa protein 1 | -0.033174 |
| YAP1 | Yes-associated protein 1 | -0.0310805 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0310723 |
| TMEM123 | transmembrane protein 123 | -0.0306509 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0301929 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0301662 |
| CDK6 | cyclin-dependent kinase 6 | -0.0299596 |
| USP34 | ubiquitin specific peptidase 34 | -0.0299439 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0293318 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0291332 |
| RPS20 | ribosomal protein S20 | -0.028827 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.028775 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0287488 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0286083 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0283698 |
| RPL23 | ribosomal protein L23 | -0.028194 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0279638 |
| PTMS | parathymosin | -0.0277919 |
| MAP4 | microtubule-associated protein 4 | -0.0275851 |
| POTEF | POTE ankyrin domain family, member F | -0.0273495 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0272783 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0272075 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0271965 |
| RPL31 | ribosomal protein L31 | -0.0266802 |
| RPS5 | ribosomal protein S5 | -0.0263354 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0262979 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0261722 |
| RPS24 | ribosomal protein S24 | -0.0261402 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0260422 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.0258194 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0251004 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0250038 |
| EGR1 | early growth response 1 | -0.0249672 |
| RPL35A | ribosomal protein L35a | -0.0249257 |
| TPI1 | triosephosphate isomerase 1 | -0.0244205 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0243876 |
| BCHE | butyrylcholinesterase | -0.0242909 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0242894 |
| RPLP2 | ribosomal protein, large, P2 | -0.024021 |
| RPL27A | ribosomal protein L27a | -0.0239495 |
| RPS14 | ribosomal protein S14 | -0.0239025 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0237998 |
| GCG | glucagon | -0.0237284 |
| HMGA1 | high mobility group AT-hook 1 | -0.0236314 |
| RTN3 | reticulon 3 | -0.0235765 |
| RPL28 | ribosomal protein L28 | -0.0235451 |
| S100A6 | S100 calcium binding protein A6 | -0.0234591 |
| ACTG1 | actin gamma 1 | -0.0232912 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0231832 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0230756 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0230082 |
| H1-0 | H1.0 linker histone | -0.0228927 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.022814 |
| LMO7 | LIM domain 7 | -0.0227163 |
| RPL32 | ribosomal protein L32 | -0.0226952 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0226806 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0224774 |
| XPO1 | exportin 1 | -0.0223634 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0221638 |
