| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Quinestrol perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Quinestrol_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.244981 |
| CDH13 | cadherin 13 | 0.128801 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.126373 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.117506 |
| NDRG1 | N-myc downstream regulated 1 | 0.109654 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0951153 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0937182 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0834873 |
| CADM1 | cell adhesion molecule 1 | 0.0832121 |
| FBN1 | fibrillin 1 | 0.0716718 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.06828 |
| COL5A1 | collagen, type V, alpha 1 | 0.0649572 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0643564 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0629584 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0623928 |
| CANX | calnexin | 0.0575076 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.053442 |
| PDE10A | phosphodiesterase 10A | 0.0532995 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0518642 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0497138 |
| PTK2 | protein tyrosine kinase 2 | 0.0496529 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0478101 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0465892 |
| FMNL2 | formin-like 2 | 0.044097 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.043654 |
| NAV2 | neuron navigator 2 | 0.0435036 |
| FNIP1 | folliculin interacting protein 1 | 0.0429026 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0428863 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0426539 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0402387 |
| GOLGB1 | golgin B1 | 0.0398373 |
| ARRDC3 | arrestin domain containing 3 | 0.0391886 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.039016 |
| ATXN1 | ataxin 1 | 0.038523 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0382635 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0381346 |
| SQSTM1 | sequestosome 1 | 0.0378809 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0377367 |
| EFNA5 | ephrin-A5 | 0.0376801 |
| RUNX1 | runt-related transcription factor 1 | 0.0373156 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0363399 |
| EGFR | epidermal growth factor receptor | 0.0359035 |
| COL1A2 | collagen, type I, alpha 2 | 0.0358636 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0354671 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0338029 |
| MAP4 | microtubule-associated protein 4 | 0.0337969 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0333501 |
| CCNY | cyclin Y | 0.033137 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0330757 |
| RND3 | Rho family GTPase 3 | 0.0330517 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0327561 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0327046 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0325337 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0323187 |
| SPAG9 | sperm associated antigen 9 | 0.0322876 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0322021 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0317684 |
| CALU | calumenin | 0.0315884 |
| CDK13 | cyclin-dependent kinase 13 | 0.0314992 |
| ASPH | aspartate beta-hydroxylase | 0.0311731 |
| GOLGA4 | golgin A4 | 0.0310878 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0307604 |
| MYO10 | myosin X | 0.0303038 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0300594 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.030012 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0298948 |
| CALR | calreticulin | 0.0295801 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0291817 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0287707 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0285311 |
| CMIP | c-Maf inducing protein | 0.0284038 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0284001 |
| ADM | adrenomedullin | 0.0282792 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0282765 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0280665 |
| HYOU1 | hypoxia up-regulated 1 | 0.0276118 |
| GANAB | glucosidase, alpha; neutral AB | 0.0275297 |
| MTDH | metadherin | 0.0274619 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0273706 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0271986 |
| HDAC9 | histone deacetylase 9 | 0.0268592 |
| MRTFA | myocardin related transcription factor A | 0.0267735 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0266574 |
| JUN | jun proto-oncogene | 0.0265066 |
| FUS | FUS RNA binding protein | 0.026217 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0258676 |
| AHNAK | AHNAK nucleoprotein | 0.0256532 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0254917 |
| TNS1 | tensin 1 | 0.0254833 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0253772 |
| OGA | O-GlcNAcase | 0.0252732 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0251406 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.025025 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0245035 |
| STC2 | stanniocalcin 2 | 0.0240652 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0238246 |
| CD109 | CD109 molecule | 0.0236952 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0236351 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0234416 |
| SDC2 | syndecan 2 | 0.0233951 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.386595 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.295356 |
| MT2A | metallothionein 2A | -0.17948 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.157521 |
| TMSB10 | thymosin beta 10 | -0.0976858 |
| VIM | vimentin | -0.0970085 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0930893 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0696283 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0666902 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0631381 |
| CD44 | CD44 molecule (Indian blood group) | -0.0619229 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0467776 |
| FTL | ferritin, light polypeptide | -0.0445668 |
| LDHA | lactate dehydrogenase A | -0.0426029 |
| RPL35A | ribosomal protein L35a | -0.0415906 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0396919 |
| B2M | beta-2-microglobulin | -0.039169 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0381341 |
| MT1X | metallothionein 1X | -0.0375274 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0363728 |
| PALLD | palladin, cytoskeletal associated protein | -0.0362712 |
| S100A9 | S100 calcium binding protein A9 | -0.0362416 |
| PKM | pyruvate kinase, muscle | -0.0358002 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0348096 |
| EGR1 | early growth response 1 | -0.0341055 |
| HLA-B | major histocompatibility complex, class I, B | -0.033923 |
| POSTN | periostin, osteoblast specific factor | -0.0334383 |
| MAP1B | microtubule-associated protein 1B | -0.0322361 |
| PFN1 | profilin 1 | -0.0317915 |
| OSMR | oncostatin M receptor | -0.0316396 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0308283 |
| GLIS3 | GLIS family zinc finger 3 | -0.0291733 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0289724 |
| TAPBP | TAP binding protein (tapasin) | -0.0287031 |
| LOX | lysyl oxidase | -0.0279197 |
| RPS19 | ribosomal protein S19 | -0.0278058 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0274676 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0269043 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.026811 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0265256 |
| RPL19 | ribosomal protein L19 | -0.0262964 |
| PTMA | prothymosin, alpha | -0.0261893 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0261745 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0261152 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0258287 |
| HAS2 | hyaluronan synthase 2 | -0.0245489 |
| BSG | basigin (Ok blood group) | -0.0245467 |
| HMGA1 | high mobility group AT-hook 1 | -0.0241632 |
| TPI1 | triosephosphate isomerase 1 | -0.0238671 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0236365 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0236107 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0235442 |
| RPL8 | ribosomal protein L8 | -0.0218406 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.021546 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0211038 |
| RPL23 | ribosomal protein L23 | -0.0208826 |
| AXL | AXL receptor tyrosine kinase | -0.0207618 |
| STC1 | stanniocalcin 1 | -0.0207165 |
| S100A6 | S100 calcium binding protein A6 | -0.0203532 |
| JAK2 | Janus kinase 2 | -0.0203472 |
| RPL28 | ribosomal protein L28 | -0.0200225 |
| RPS6 | ribosomal protein S6 | -0.0200202 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0199957 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0196663 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0196512 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0196066 |
| TAGLN2 | transgelin 2 | -0.0194285 |
| RPS8 | ribosomal protein S8 | -0.0191957 |
| TMSB4X | thymosin beta 4, X-linked | -0.0189362 |
| HLA-A | major histocompatibility complex, class I, A | -0.0188368 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0187669 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0187246 |
| INHBA | inhibin, beta A | -0.0187037 |
| RPL12 | ribosomal protein L12 | -0.0180357 |
| NRP1 | neuropilin 1 | -0.0177916 |
| POTEF | POTE ankyrin domain family, member F | -0.01767 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0175822 |
| RACK1 | receptor for activated C kinase 1 | -0.017525 |
| RPL36 | ribosomal protein L36 | -0.0170973 |
| SBF2 | SET binding factor 2 | -0.0170759 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0168677 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0167953 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.0167888 |
| RPL26 | ribosomal protein L26 | -0.0165715 |
| LIMA1 | LIM domain and actin binding 1 | -0.0165055 |
| MYADM | myeloid-associated differentiation marker | -0.0165024 |
| RPS14 | ribosomal protein S14 | -0.0163825 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0160372 |
| CST3 | cystatin C | -0.0159343 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0159178 |
| FAM20C | family with sequence similarity 20, member C | -0.0158619 |
| RPL32 | ribosomal protein L32 | -0.015817 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0157988 |
| DUSP6 | dual specificity phosphatase 6 | -0.0157189 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.015454 |
| UBC | ubiquitin C | -0.0154531 |
| VCAN | versican | -0.0152309 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0152206 |
| MX2 | MX dynamin-like GTPase 2 | -0.0149522 |
| RPS5 | ribosomal protein S5 | -0.014917 |
