| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Quinestrol perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Quinestrol_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.156246 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0907536 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0864058 |
| SVIL | supervillin | 0.0702311 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0586533 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0557728 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0510817 |
| ATXN1 | ataxin 1 | 0.0481543 |
| ASPH | aspartate beta-hydroxylase | 0.0481057 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0444035 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0436195 |
| FAM107B | family with sequence similarity 107, member B | 0.0419057 |
| FMNL2 | formin-like 2 | 0.0404563 |
| TNS1 | tensin 1 | 0.0393027 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0390566 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0389289 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0385859 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0384498 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0380615 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0366498 |
| DTNA | dystrobrevin, alpha | 0.0347157 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0345264 |
| RUNX1 | runt-related transcription factor 1 | 0.0331078 |
| INSIG2 | insulin induced gene 2 | 0.0325055 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0323505 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0319616 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0318778 |
| NGLY1 | N-glycanase 1 | 0.0317922 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0312617 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0311978 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.030124 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0298915 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0296962 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0296797 |
| NUP58 | nucleoporin 58 | 0.0292377 |
| MYO6 | myosin VI | 0.0285444 |
| ANO6 | anoctamin 6 | 0.0275751 |
| USP34 | ubiquitin specific peptidase 34 | 0.027449 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0270952 |
| MYO1B | myosin IB | 0.0270674 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0268518 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0264279 |
| WWC2 | WW and C2 domain containing 2 | 0.0260944 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0258488 |
| DST | dystonin | 0.0254729 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0251884 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0248388 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0246778 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0244089 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0242462 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0241834 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0233257 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0232046 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0230917 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0228819 |
| STC2 | stanniocalcin 2 | 0.0227072 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0220234 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0218718 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0213432 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0210995 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0208462 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0207094 |
| FAM13A | family with sequence similarity 13, member A | 0.0203537 |
| KYNU | kynureninase | 0.0202389 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0201968 |
| MCU | mitochondrial calcium uniporter | 0.0199871 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0199446 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.019862 |
| TAOK1 | TAO kinase 1 | 0.019784 |
| SPAG9 | sperm associated antigen 9 | 0.0195412 |
| ZNF292 | zinc finger protein 292 | 0.0195184 |
| FBXO42 | F-box protein 42 | 0.0194058 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0191357 |
| HELZ | helicase with zinc finger | 0.0191226 |
| ITGA6 | integrin, alpha 6 | 0.0189637 |
| CLIC4 | chloride intracellular channel 4 | 0.0189309 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0187306 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0186531 |
| DSPP | dentin sialophosphoprotein | 0.0184346 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.018249 |
| TLE4 | transducin-like enhancer of split 4 | 0.0182479 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0181316 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0177003 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0176993 |
| ZNF638 | zinc finger protein 638 | 0.0176754 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0175071 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0175037 |
| FRMD5 | FERM domain containing 5 | 0.0174623 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.017411 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0173813 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0173781 |
| CP | ceruloplasmin (ferroxidase) | 0.0173455 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0173037 |
| ARRDC3 | arrestin domain containing 3 | 0.0172496 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0172222 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0169857 |
| INTS6 | integrator complex subunit 6 | 0.0169754 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0168987 |
| USP37 | ubiquitin specific peptidase 37 | 0.0168937 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0167697 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.298013 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.257959 |
| IGF2 | insulin-like growth factor 2 | -0.24961 |
| C3 | complement component 3 | -0.212332 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.15263 |
| FN1 | fibronectin 1 | -0.148701 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.140633 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0974685 |
| GPC3 | glypican 3 | -0.0973438 |
| A2M | alpha-2-macroglobulin | -0.0776648 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.074625 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0739713 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0707377 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0645242 |
| MT2A | metallothionein 2A | -0.0626964 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0618173 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0612293 |
| TMSB10 | thymosin beta 10 | -0.0577858 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0551698 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0528383 |
| TRIM26 | tripartite motif containing 26 | -0.052421 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.052319 |
| APOA2 | apolipoprotein A-II | -0.052176 |
| RPL31 | ribosomal protein L31 | -0.0517544 |
| RPL37A | ribosomal protein L37a | -0.0517487 |
| LOC112694756 | uncharaterized LOC112694756 | -0.051143 |
| RPS6 | ribosomal protein S6 | -0.0485911 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0473961 |
| RPS12 | ribosomal protein S12 | -0.0460413 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0454416 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0454188 |
| EGR1 | early growth response 1 | -0.0441871 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0438403 |
| RPL23 | ribosomal protein L23 | -0.0413399 |
| CFB | complement factor B | -0.0410933 |
| PEG10 | paternally expressed 10 | -0.0402211 |
| RRBP1 | ribosome binding protein 1 | -0.0398428 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0397333 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0395237 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0390924 |
| RPLP1 | ribosomal protein, large, P1 | -0.0386833 |
| FTL | ferritin, light polypeptide | -0.0383363 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0382467 |
| ACTN4 | actinin, alpha 4 | -0.0382236 |
| RPS24 | ribosomal protein S24 | -0.0369748 |
| CPE | carboxypeptidase E | -0.0348692 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.0346042 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0345458 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0344345 |
| RPS8 | ribosomal protein S8 | -0.0333164 |
| RPL10A | ribosomal protein L10a | -0.032861 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0324044 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0315985 |
| RACK1 | receptor for activated C kinase 1 | -0.0314532 |
| PKM | pyruvate kinase, muscle | -0.0313126 |
| APOE | apolipoprotein E | -0.0309845 |
| CALD1 | caldesmon 1 | -0.0308306 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0306505 |
| GPC6 | glypican 6 | -0.0304607 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0300878 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0300821 |
| RPL11 | ribosomal protein L11 | -0.0292407 |
| RPS19 | ribosomal protein S19 | -0.0284366 |
| FOXN3 | forkhead box N3 | -0.0282592 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0279404 |
| RPS13 | ribosomal protein S13 | -0.0276069 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0275028 |
| RPL35A | ribosomal protein L35a | -0.0273995 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | -0.0270497 |
| RPL26 | ribosomal protein L26 | -0.0270032 |
| HLF | hepatic leukemia factor | -0.0269171 |
| RPLP2 | ribosomal protein, large, P2 | -0.0266112 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0264245 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0261178 |
| IER3 | immediate early response 3 | -0.0260641 |
| PTCHD4 | patched domain containing 4 | -0.0260327 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0259446 |
| LYZ | lysozyme | -0.0256809 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0255201 |
| RPL37 | ribosomal protein L37 | -0.0254226 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0253794 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0253139 |
| RPL34 | ribosomal protein L34 | -0.0252586 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0250749 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.025035 |
| SYNJ2 | synaptojanin 2 | -0.0245976 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0244142 |
| RPS25 | ribosomal protein S25 | -0.0243646 |
| RPL30 | ribosomal protein L30 | -0.0242263 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0241454 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0240099 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0239843 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0239293 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0238985 |
| IQSEC1 | IQ motif and Sec7 domain 1 | -0.0238893 |
| RPS21 | ribosomal protein S21 | -0.0237902 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0233707 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | -0.023347 |
| RPS5 | ribosomal protein S5 | -0.0233109 |
| GNAS | GNAS complex locus | -0.0226083 |
