| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Quinestrol perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Quinestrol_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.187829 |
| LMO7 | LIM domain 7 | 0.148422 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0913452 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0762553 |
| MYOF | myoferlin | 0.0689093 |
| CTBP2 | C-terminal binding protein 2 | 0.0532896 |
| SMAD3 | SMAD family member 3 | 0.049855 |
| SEPTIN9 | septin 9 | 0.0476818 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0459263 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0427249 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0387226 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0377404 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0362273 |
| CAPN8 | calpain 8 | 0.0354828 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.035408 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.035243 |
| GDA | guanine deaminase | 0.0348599 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0335771 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0335396 |
| KLHL29 | kelch-like family member 29 | 0.0318988 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0310554 |
| HYOU1 | hypoxia up-regulated 1 | 0.0303926 |
| ASPH | aspartate beta-hydroxylase | 0.0299658 |
| TXNRD1 | thioredoxin reductase 1 | 0.0295754 |
| RBM39 | RNA binding motif protein 39 | 0.0294062 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0291491 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0275718 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0265843 |
| AGR2 | anterior gradient 2 | 0.0265273 |
| INTS6 | integrator complex subunit 6 | 0.0265154 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0262631 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0246903 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0244594 |
| MGAM2 | maltase-glucoamylase 2 (putative) | 0.0238453 |
| GOLGB1 | golgin B1 | 0.0237308 |
| OGA | O-GlcNAcase | 0.0233936 |
| TJP1 | tight junction protein 1 | 0.0228658 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0226444 |
| ATP11A | ATPase, class VI, type 11A | 0.0225029 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0222714 |
| CDK13 | cyclin-dependent kinase 13 | 0.0221792 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0219988 |
| KCNIP4 | Kv channel interacting protein 4 | 0.0219499 |
| MEF2A | myocyte enhancer factor 2A | 0.0211956 |
| MB21D2 | Mab-21 domain containing 2 | 0.02085 |
| CLTC | clathrin, heavy chain (Hc) | 0.0205032 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.020313 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0202663 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0202021 |
| RAB10 | RAB10, member RAS oncogene family | 0.0201422 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0198507 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0198391 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0197476 |
| TOX3 | TOX high mobility group box family member 3 | 0.019635 |
| ATXN1 | ataxin 1 | 0.0196206 |
| LIPH | lipase, member H | 0.0190766 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0188808 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.018397 |
| RTN3 | reticulon 3 | 0.0183392 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0183367 |
| RCOR1 | REST corepressor 1 | 0.0181747 |
| TCF12 | transcription factor 12 | 0.0180253 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0179837 |
| ECT2 | epithelial cell transforming 2 | 0.0179825 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0179591 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0179205 |
| SQSTM1 | sequestosome 1 | 0.0178128 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0177174 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.01762 |
| RBM47 | RNA binding motif protein 47 | 0.0176131 |
| MED13 | mediator complex subunit 13 | 0.0171799 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0171065 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0169521 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0167856 |
| ZNF75D | zinc finger protein 75D | 0.0167075 |
| TMEM123 | transmembrane protein 123 | 0.0166388 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0166297 |
| STX3 | syntaxin 3 | 0.0166213 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.01659 |
| FNIP1 | folliculin interacting protein 1 | 0.0165815 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0165158 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0164308 |
| RRBP1 | ribosome binding protein 1 | 0.0162223 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.0161964 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.015891 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0157866 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0157573 |
| MAGT1 | magnesium transporter 1 | 0.0157325 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.015587 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0155624 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0155142 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0153783 |
| CANX | calnexin | 0.0153672 |
| LAMA4 | laminin, alpha 4 | 0.0152715 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0152484 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0151836 |
| AHNAK | AHNAK nucleoprotein | 0.0150744 |
| STX5 | syntaxin 5 | 0.015029 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0149786 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.014972 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.185172 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0888206 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0774957 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0747962 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0709781 |
| RPS6 | ribosomal protein S6 | -0.0637249 |
| FRMD5 | FERM domain containing 5 | -0.0567081 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0556305 |
| FLNB | filamin B, beta | -0.0548093 |
| RPL35A | ribosomal protein L35a | -0.0522404 |
| EHBP1 | EH domain binding protein 1 | -0.0521474 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0507349 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0495138 |
| CALR | calreticulin | -0.0459316 |
| PTMA | prothymosin, alpha | -0.0447714 |
| FAT1 | FAT atypical cadherin 1 | -0.0412137 |
| ITGB4 | integrin, beta 4 | -0.0404559 |
| RPL23 | ribosomal protein L23 | -0.0399447 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0397428 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0396579 |
| B2M | beta-2-microglobulin | -0.0393053 |
| POTEF | POTE ankyrin domain family, member F | -0.0392524 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0390882 |
| VEGFA | vascular endothelial growth factor A | -0.0389212 |
| RPS3 | ribosomal protein S3 | -0.0385609 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0380146 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0370914 |
| RAD51B | RAD51 paralog B | -0.036999 |
| INSIG1 | insulin induced gene 1 | -0.036733 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0347257 |
| EZR | ezrin | -0.0340238 |
| EMP1 | epithelial membrane protein 1 | -0.0338847 |
| NDRG1 | N-myc downstream regulated 1 | -0.0334031 |
| PKM | pyruvate kinase, muscle | -0.0330946 |
| KRT18 | keratin 18, type I | -0.0330555 |
| S100A11 | S100 calcium binding protein A11 | -0.0330263 |
| KRT19 | keratin 19, type I | -0.0323403 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.031133 |
| ACTN4 | actinin, alpha 4 | -0.0301714 |
| RPS19 | ribosomal protein S19 | -0.0301478 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0300211 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0294936 |
| ZNF292 | zinc finger protein 292 | -0.029161 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0290175 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0288018 |
| TMSB10 | thymosin beta 10 | -0.0286416 |
| AUTS2 | autism susceptibility candidate 2 | -0.0284293 |
| HLA-A | major histocompatibility complex, class I, A | -0.0281924 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0277299 |
| S100A6 | S100 calcium binding protein A6 | -0.0277222 |
| COBL | cordon-bleu WH2 repeat protein | -0.0276608 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0274947 |
| KRT8 | keratin 8, type II | -0.0274169 |
| LIMA1 | LIM domain and actin binding 1 | -0.0272138 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0269255 |
| HMGA1 | high mobility group AT-hook 1 | -0.0266995 |
| RPS12 | ribosomal protein S12 | -0.0260386 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0258526 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0257709 |
| NCOR2 | nuclear receptor corepressor 2 | -0.025748 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0253991 |
| RPL26 | ribosomal protein L26 | -0.0251399 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0251346 |
| CLDN4 | claudin 4 | -0.025071 |
| S100P | S100 calcium binding protein P | -0.0245703 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0244788 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0240511 |
| RPS8 | ribosomal protein S8 | -0.0234894 |
| RPS25 | ribosomal protein S25 | -0.0234725 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0233001 |
| RPL12 | ribosomal protein L12 | -0.023267 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0229583 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.022898 |
| BCL2L1 | BCL2-like 1 | -0.0228908 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0227765 |
| VCL | vinculin | -0.02275 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0227022 |
| EGR1 | early growth response 1 | -0.0225313 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0225178 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0224919 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0224771 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0224219 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0222961 |
| S100A10 | S100 calcium binding protein A10 | -0.0220083 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0219195 |
| TPM3 | tropomyosin 3 | -0.0219152 |
| RPL35 | ribosomal protein L35 | -0.0217788 |
| PFN1 | profilin 1 | -0.0216714 |
| RPL37A | ribosomal protein L37a | -0.021599 |
| LAMA5 | laminin, alpha 5 | -0.0215754 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0214186 |
| MKI67 | marker of proliferation Ki-67 | -0.0212804 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0211378 |
| RPL27 | ribosomal protein L27 | -0.0209808 |
| ABHD2 | abhydrolase domain containing 2 | -0.0207101 |
| TPI1 | triosephosphate isomerase 1 | -0.0206621 |
| S100A9 | S100 calcium binding protein A9 | -0.0206259 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0205911 |
| EXOC4 | exocyst complex component 4 | -0.0205062 |
| TPM4 | tropomyosin 4 | -0.020327 |
